SP4.H12INVITRO.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SP4.H12INVITRO.1.S.B
Gene (human)	SP4 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Sp4
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	11
Consensus	nddSGCGTGdn
GC content	65.97%
Information content (bits; total / per base)	9.678 / 0.88
Data sources	HT-SELEX
Aligned words	1417

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (12)	0.705	0.772	0.547	0.64	0.708	0.773	1.923	2.335	10.653	39.056

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.599	0.579	0.558	0.548	0.536	0.532
Non-Methyl HT-SELEX, 2 experiments	best	0.607	0.589	0.563	0.554	0.537	0.535

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Sp1-like {2.3.1.1} (TFClass)
TFClass ID	TFClass: 2.3.1.1.4
HGNC	HGNC:11209
MGI	MGI:107595
EntrezGene (human)	GeneID:6671 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	SP4_HUMAN
UniProt ID (mouse)	SP4_MOUSE
UniProt AC (human)	Q02446 (TFClass)
UniProt AC (mouse)	Q62445 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	SP4.H12INVITRO.1.S.B.pcm
PWM	SP4.H12INVITRO.1.S.B.pwm
PFM	SP4.H12INVITRO.1.S.B.pfm
Alignment	SP4.H12INVITRO.1.S.B.words.tsv
Threshold to P-value map	SP4.H12INVITRO.1.S.B.thr
Motif in other formats
JASPAR format	SP4.H12INVITRO.1.S.B_jaspar_format.txt
MEME format	SP4.H12INVITRO.1.S.B_meme_format.meme
Transfac format	SP4.H12INVITRO.1.S.B_transfac_format.txt
Homer format	SP4.H12INVITRO.1.S.B_homer_format_0.001.txt SP4.H12INVITRO.1.S.B_homer_format_0.0005.txt SP4.H12INVITRO.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	339.75	253.75	498.75	324.75
02	307.75	158.75	354.75	595.75
03	302.0	80.0	796.0	239.0
04	91.0	468.0	854.0	4.0
05	18.0	0.0	1399.0	0.0
06	20.0	1293.0	0.0	104.0
07	7.0	0.0	1410.0	0.0
08	10.0	0.0	131.0	1276.0
09	70.0	13.0	1225.0	109.0
10	492.0	96.0	549.0	280.0
11	354.25	303.25	399.25	360.25

PFM

	A	C	G	T
01	0.24	0.179	0.352	0.229
02	0.217	0.112	0.25	0.42
03	0.213	0.056	0.562	0.169
04	0.064	0.33	0.603	0.003
05	0.013	0.0	0.987	0.0
06	0.014	0.912	0.0	0.073
07	0.005	0.0	0.995	0.0
08	0.007	0.0	0.092	0.9
09	0.049	0.009	0.865	0.077
10	0.347	0.068	0.387	0.198
11	0.25	0.214	0.282	0.254

PWM

	A	C	G	T
01	-0.042	-0.332	0.341	-0.086
02	-0.14	-0.796	0.001	0.518
03	-0.159	-1.471	0.807	-0.391
04	-1.345	0.277	0.877	-4.115
05	-2.889	-5.28	1.37	-5.28
06	-2.793	1.291	-5.28	-1.213
07	-3.699	-5.28	1.378	-5.28
08	-3.406	-5.28	-0.986	1.278
09	-1.601	-3.18	1.237	-1.167
10	0.327	-1.292	0.436	-0.234
11	0.0	-0.155	0.119	0.017

Standard thresholds

P-value	Threshold
0.001	4.95227
0.0005	5.863485
0.0001	7.56005