SP4.H12CORE.2.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SP4.H12CORE.2.P.B
Gene (human)	SP4 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Sp4
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	21
Consensus	dRRRGGMGGRGvndRRRvdvR
GC content	71.02%
Information content (bits; total / per base)	15.18 / 0.723
Data sources	ChIP-Seq
Aligned words	970

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (12)	0.689	0.837	0.515	0.669	0.785	0.924	2.952	4.149	7.017	58.398

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.504	0.508	0.498	0.502	0.497	0.5
Non-Methyl HT-SELEX, 2 experiments	best	0.505	0.508	0.5	0.502	0.498	0.501

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Sp1-like {2.3.1.1} (TFClass)
TFClass ID	TFClass: 2.3.1.1.4
HGNC	HGNC:11209
MGI	MGI:107595
EntrezGene (human)	GeneID:6671 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	SP4_HUMAN
UniProt ID (mouse)	SP4_MOUSE
UniProt AC (human)	Q02446 (TFClass)
UniProt AC (mouse)	Q62445 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	SP4.H12CORE.2.P.B.pcm
PWM	SP4.H12CORE.2.P.B.pwm
PFM	SP4.H12CORE.2.P.B.pfm
Alignment	SP4.H12CORE.2.P.B.words.tsv
Threshold to P-value map	SP4.H12CORE.2.P.B.thr
Motif in other formats
JASPAR format	SP4.H12CORE.2.P.B_jaspar_format.txt
MEME format	SP4.H12CORE.2.P.B_meme_format.meme
Transfac format	SP4.H12CORE.2.P.B_transfac_format.txt
Homer format	SP4.H12CORE.2.P.B_homer_format_0.001.txt SP4.H12CORE.2.P.B_homer_format_0.0005.txt SP4.H12CORE.2.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	410.0	94.0	279.0	187.0
02	225.0	47.0	644.0	54.0
03	206.0	15.0	602.0	147.0
04	261.0	4.0	683.0	22.0
05	12.0	4.0	949.0	5.0
06	8.0	4.0	954.0	4.0
07	329.0	586.0	4.0	51.0
08	57.0	3.0	893.0	17.0
09	23.0	6.0	839.0	102.0
10	335.0	23.0	556.0	56.0
11	92.0	26.0	825.0	27.0
12	227.0	482.0	173.0	88.0
13	196.0	354.0	230.0	190.0
14	245.0	76.0	398.0	251.0
15	170.0	60.0	642.0	98.0
16	243.0	74.0	620.0	33.0
17	275.0	86.0	573.0	36.0
18	202.0	128.0	557.0	83.0
19	224.0	136.0	468.0	142.0
20	181.0	129.0	559.0	101.0
21	216.0	101.0	580.0	73.0

PFM

	A	C	G	T
01	0.423	0.097	0.288	0.193
02	0.232	0.048	0.664	0.056
03	0.212	0.015	0.621	0.152
04	0.269	0.004	0.704	0.023
05	0.012	0.004	0.978	0.005
06	0.008	0.004	0.984	0.004
07	0.339	0.604	0.004	0.053
08	0.059	0.003	0.921	0.018
09	0.024	0.006	0.865	0.105
10	0.345	0.024	0.573	0.058
11	0.095	0.027	0.851	0.028
12	0.234	0.497	0.178	0.091
13	0.202	0.365	0.237	0.196
14	0.253	0.078	0.41	0.259
15	0.175	0.062	0.662	0.101
16	0.251	0.076	0.639	0.034
17	0.284	0.089	0.591	0.037
18	0.208	0.132	0.574	0.086
19	0.231	0.14	0.482	0.146
20	0.187	0.133	0.576	0.104
21	0.223	0.104	0.598	0.075

PWM

	A	C	G	T
01	0.522	-0.937	0.139	-0.258
02	-0.074	-1.612	0.972	-1.478
03	-0.162	-2.682	0.905	-0.496
04	0.073	-3.754	1.031	-2.332
05	-2.879	-3.754	1.359	-3.593
06	-3.224	-3.754	1.364	-3.754
07	0.303	0.878	-3.754	-1.533
08	-1.425	-3.946	1.298	-2.569
09	-2.29	-3.454	1.236	-0.856
10	0.321	-2.29	0.826	-1.442
11	-0.958	-2.176	1.219	-2.14
12	-0.066	0.683	-0.335	-1.001
13	-0.211	0.376	-0.053	-0.242
14	0.01	-1.145	0.493	0.034
15	-0.352	-1.375	0.969	-0.896
16	0.002	-1.171	0.934	-1.951
17	0.125	-1.024	0.856	-1.868
18	-0.181	-0.633	0.828	-1.059
19	-0.079	-0.573	0.654	-0.53
20	-0.29	-0.625	0.831	-0.866
21	-0.115	-0.866	0.868	-1.184

Standard thresholds

P-value	Threshold
0.001	3.10176
0.0005	4.22921
0.0001	6.58111