SP3.H12INVIVO.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SP3.H12INVIVO.1.S.B
Gene (human)	SP3 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Sp3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	14
Consensus	vndRKGGGCGTGKb
GC content	71.51%
Information content (bits; total / per base)	14.188 / 1.013
Data sources	HT-SELEX
Aligned words	9732

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.835	0.849	0.683	0.698	0.895	0.908	3.266	3.408	29.523	41.244
Mouse	9 (45)	0.834	0.906	0.707	0.811	0.855	0.911	3.365	3.788	28.824	76.585

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.823	0.793	0.703	0.694	0.598	0.616
Non-Methyl HT-SELEX, 2 experiments	best	0.92	0.89	0.788	0.774	0.64	0.665

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Sp1-like {2.3.1.1} (TFClass)
TFClass ID	TFClass: 2.3.1.1.3
HGNC	HGNC:11208
MGI	MGI:1277166
EntrezGene (human)	GeneID:6670 (SSTAR profile)
EntrezGene (mouse)	GeneID:20687 (SSTAR profile)
UniProt ID (human)	SP3_HUMAN
UniProt ID (mouse)	SP3_MOUSE
UniProt AC (human)	Q02447 (TFClass)
UniProt AC (mouse)	O70494 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 9 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	SP3.H12INVIVO.1.S.B.pcm
PWM	SP3.H12INVIVO.1.S.B.pwm
PFM	SP3.H12INVIVO.1.S.B.pfm
Alignment	SP3.H12INVIVO.1.S.B.words.tsv
Threshold to P-value map	SP3.H12INVIVO.1.S.B.thr
Motif in other formats
JASPAR format	SP3.H12INVIVO.1.S.B_jaspar_format.txt
MEME format	SP3.H12INVIVO.1.S.B_meme_format.meme
Transfac format	SP3.H12INVIVO.1.S.B_transfac_format.txt
Homer format	SP3.H12INVIVO.1.S.B_homer_format_0.001.txt SP3.H12INVIVO.1.S.B_homer_format_0.0005.txt SP3.H12INVIVO.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1949.25	1892.25	4054.25	1836.25
02	2435.25	1987.25	3343.25	1966.25
03	2967.0	971.0	3947.0	1847.0
04	2301.0	252.0	6479.0	700.0
05	1056.0	10.0	4147.0	4519.0
06	657.0	4.0	9038.0	33.0
07	11.0	16.0	9701.0	4.0
08	4.0	0.0	9726.0	2.0
09	92.0	9632.0	0.0	8.0
10	3.0	0.0	9727.0	2.0
11	44.0	19.0	1339.0	8330.0
12	1011.0	115.0	7893.0	713.0
13	1249.75	641.75	6395.75	1444.75
14	1172.5	4073.5	2030.5	2455.5

PFM

	A	C	G	T
01	0.2	0.194	0.417	0.189
02	0.25	0.204	0.344	0.202
03	0.305	0.1	0.406	0.19
04	0.236	0.026	0.666	0.072
05	0.109	0.001	0.426	0.464
06	0.068	0.0	0.929	0.003
07	0.001	0.002	0.997	0.0
08	0.0	0.0	0.999	0.0
09	0.009	0.99	0.0	0.001
10	0.0	0.0	0.999	0.0
11	0.005	0.002	0.138	0.856
12	0.104	0.012	0.811	0.073
13	0.128	0.066	0.657	0.148
14	0.12	0.419	0.209	0.252

PWM

	A	C	G	T
01	-0.221	-0.251	0.51	-0.281
02	0.001	-0.202	0.318	-0.213
03	0.198	-0.917	0.483	-0.275
04	-0.056	-2.259	0.979	-1.243
05	-0.833	-5.289	0.533	0.619
06	-1.307	-5.958	1.312	-4.234
07	-5.21	-4.891	1.382	-5.958
08	-5.958	-6.967	1.385	-6.34
09	-3.251	1.375	-6.967	-5.466
10	-6.131	-6.967	1.385	-6.34
11	-3.963	-4.739	-0.596	1.23
12	-0.877	-3.033	1.176	-1.225
13	-0.665	-1.33	0.966	-0.521
14	-0.729	0.515	-0.181	0.009

Standard thresholds

P-value	Threshold
0.001	2.01271
0.0005	3.59241
0.0001	6.84066