SP3.H12INVITRO.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SP3.H12INVITRO.1.S.B
Gene (human)	SP3 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Sp3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	11
Consensus	nddGGGCGKdn
GC content	69.6%
Information content (bits; total / per base)	9.781 / 0.889
Data sources	HT-SELEX
Aligned words	8657

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.84	0.852	0.68	0.71	0.878	0.893	2.955	3.093	31.222	43.824
Mouse	9 (45)	0.826	0.898	0.715	0.819	0.838	0.893	3.025	3.401	26.347	62.959

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.839	0.804	0.725	0.708	0.613	0.626
Non-Methyl HT-SELEX, 2 experiments	best	0.924	0.895	0.793	0.78	0.641	0.667

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Sp1-like {2.3.1.1} (TFClass)
TFClass ID	TFClass: 2.3.1.1.3
HGNC	HGNC:11208
MGI	MGI:1277166
EntrezGene (human)	GeneID:6670 (SSTAR profile)
EntrezGene (mouse)	GeneID:20687 (SSTAR profile)
UniProt ID (human)	SP3_HUMAN
UniProt ID (mouse)	SP3_MOUSE
UniProt AC (human)	Q02447 (TFClass)
UniProt AC (mouse)	O70494 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 9 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	SP3.H12INVITRO.1.S.B.pcm
PWM	SP3.H12INVITRO.1.S.B.pwm
PFM	SP3.H12INVITRO.1.S.B.pfm
Alignment	SP3.H12INVITRO.1.S.B.words.tsv
Threshold to P-value map	SP3.H12INVITRO.1.S.B.thr
Motif in other formats
JASPAR format	SP3.H12INVITRO.1.S.B_jaspar_format.txt
MEME format	SP3.H12INVITRO.1.S.B_meme_format.meme
Transfac format	SP3.H12INVITRO.1.S.B_transfac_format.txt
Homer format	SP3.H12INVITRO.1.S.B_homer_format_0.001.txt SP3.H12INVITRO.1.S.B_homer_format_0.0005.txt SP3.H12INVITRO.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2033.25	1754.25	2816.25	2053.25
02	1862.5	1188.5	4254.5	1351.5
03	1300.0	504.0	2556.0	4297.0
04	1363.0	5.0	7270.0	19.0
05	24.0	39.0	8476.0	118.0
06	1.0	0.0	8620.0	36.0
07	1040.0	7098.0	0.0	519.0
08	129.0	8.0	8433.0	87.0
09	256.0	380.0	2891.0	5130.0
10	1522.25	431.25	4774.25	1929.25
11	1861.75	1416.75	3365.75	2012.75

PFM

	A	C	G	T
01	0.235	0.203	0.325	0.237
02	0.215	0.137	0.491	0.156
03	0.15	0.058	0.295	0.496
04	0.157	0.001	0.84	0.002
05	0.003	0.005	0.979	0.014
06	0.0	0.0	0.996	0.004
07	0.12	0.82	0.0	0.06
08	0.015	0.001	0.974	0.01
09	0.03	0.044	0.334	0.593
10	0.176	0.05	0.551	0.223
11	0.215	0.164	0.389	0.232

PWM

	A	C	G	T
01	-0.062	-0.21	0.263	-0.053
02	-0.15	-0.599	0.675	-0.47
03	-0.509	-1.454	0.166	0.685
04	-0.462	-5.698	1.211	-4.624
05	-4.413	-3.961	1.364	-2.891
06	-6.497	-6.863	1.381	-4.036
07	-0.732	1.187	-6.863	-1.425
08	-2.804	-5.352	1.359	-3.189
09	-2.127	-1.735	0.289	0.862
10	-0.351	-1.609	0.791	-0.115
11	-0.15	-0.423	0.441	-0.072

Standard thresholds

P-value	Threshold
0.001	4.97176
0.0005	5.894575
0.0001	7.51802