SP3.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SP3.H12INVITRO.0.P.B
Gene (human)	SP3 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Sp3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	12
Consensus	nRdRGGMGGRRh
GC content	74.52%
Information content (bits; total / per base)	10.175 / 0.848
Data sources	ChIP-Seq
Aligned words	891

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.847	0.857	0.675	0.691	0.924	0.939	3.666	3.87	23.678	44.31
Mouse	9 (45)	0.839	0.914	0.736	0.85	0.875	0.925	3.685	4.183	36.018	85.056

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.768	0.718	0.668	0.646	0.581	0.588
Non-Methyl HT-SELEX, 2 experiments	best	0.846	0.793	0.729	0.703	0.606	0.621

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Sp1-like {2.3.1.1} (TFClass)
TFClass ID	TFClass: 2.3.1.1.3
HGNC	HGNC:11208
MGI	MGI:1277166
EntrezGene (human)	GeneID:6670 (SSTAR profile)
EntrezGene (mouse)	GeneID:20687 (SSTAR profile)
UniProt ID (human)	SP3_HUMAN
UniProt ID (mouse)	SP3_MOUSE
UniProt AC (human)	Q02447 (TFClass)
UniProt AC (mouse)	O70494 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 9 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	SP3.H12INVITRO.0.P.B.pcm
PWM	SP3.H12INVITRO.0.P.B.pwm
PFM	SP3.H12INVITRO.0.P.B.pfm
Alignment	SP3.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	SP3.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	SP3.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	SP3.H12INVITRO.0.P.B_meme_format.meme
Transfac format	SP3.H12INVITRO.0.P.B_transfac_format.txt
Homer format	SP3.H12INVITRO.0.P.B_homer_format_0.001.txt SP3.H12INVITRO.0.P.B_homer_format_0.0005.txt SP3.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	320.0	158.0	256.0	157.0
02	233.0	104.0	500.0	54.0
03	161.0	41.0	499.0	190.0
04	218.0	22.0	625.0	26.0
05	38.0	18.0	813.0	22.0
06	10.0	5.0	866.0	10.0
07	200.0	627.0	0.0	64.0
08	69.0	27.0	782.0	13.0
09	18.0	8.0	767.0	98.0
10	255.0	25.0	550.0	61.0
11	135.0	60.0	650.0	46.0
12	211.0	474.0	91.0	115.0

PFM

	A	C	G	T
01	0.359	0.177	0.287	0.176
02	0.262	0.117	0.561	0.061
03	0.181	0.046	0.56	0.213
04	0.245	0.025	0.701	0.029
05	0.043	0.02	0.912	0.025
06	0.011	0.006	0.972	0.011
07	0.224	0.704	0.0	0.072
08	0.077	0.03	0.878	0.015
09	0.02	0.009	0.861	0.11
10	0.286	0.028	0.617	0.068
11	0.152	0.067	0.73	0.052
12	0.237	0.532	0.102	0.129

PWM

	A	C	G	T
01	0.36	-0.34	0.138	-0.347
02	0.045	-0.753	0.804	-1.394
03	-0.322	-1.659	0.802	-0.158
04	-0.021	-2.248	1.027	-2.092
05	-1.732	-2.433	1.289	-2.248
06	-2.954	-3.512	1.352	-2.954
07	-0.107	1.03	-4.884	-1.229
08	-1.155	-2.057	1.25	-2.726
09	-2.433	-3.142	1.231	-0.811
10	0.134	-2.129	0.899	-1.275
11	-0.496	-1.291	1.066	-1.549
12	-0.054	0.751	-0.884	-0.654

Standard thresholds

P-value	Threshold
0.001	4.69237
0.0005	5.53341
0.0001	7.255825