SP3.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SP3.H12CORE.0.P.B
Gene (human)	SP3 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Sp3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	19
Consensus	vvvbvnRKGGGCGGGGCYd
GC content	78.42%
Information content (bits; total / per base)	18.088 / 0.952
Data sources	ChIP-Seq
Aligned words	996

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.826	0.844	0.665	0.68	0.903	0.92	3.948	4.189	21.252	47.357
Mouse	9 (45)	0.851	0.926	0.772	0.882	0.88	0.936	4.357	5.095	44.009	95.959

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.762	0.728	0.643	0.639	0.562	0.58
Non-Methyl HT-SELEX, 2 experiments	best	0.857	0.811	0.714	0.701	0.596	0.617

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Sp1-like {2.3.1.1} (TFClass)
TFClass ID	TFClass: 2.3.1.1.3
HGNC	HGNC:11208
MGI	MGI:1277166
EntrezGene (human)	GeneID:6670 (SSTAR profile)
EntrezGene (mouse)	GeneID:20687 (SSTAR profile)
UniProt ID (human)	SP3_HUMAN
UniProt ID (mouse)	SP3_MOUSE
UniProt AC (human)	Q02447 (TFClass)
UniProt AC (mouse)	O70494 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 9 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	SP3.H12CORE.0.P.B.pcm
PWM	SP3.H12CORE.0.P.B.pwm
PFM	SP3.H12CORE.0.P.B.pfm
Alignment	SP3.H12CORE.0.P.B.words.tsv
Threshold to P-value map	SP3.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	SP3.H12CORE.0.P.B_jaspar_format.txt
MEME format	SP3.H12CORE.0.P.B_meme_format.meme
Transfac format	SP3.H12CORE.0.P.B_transfac_format.txt
Homer format	SP3.H12CORE.0.P.B_homer_format_0.001.txt SP3.H12CORE.0.P.B_homer_format_0.0005.txt SP3.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	152.0	334.0	392.0	118.0
02	171.0	295.0	457.0	73.0
03	138.0	306.0	461.0	91.0
04	93.0	239.0	522.0	142.0
05	158.0	296.0	420.0	122.0
06	356.0	176.0	291.0	173.0
07	255.0	88.0	621.0	32.0
08	96.0	2.0	694.0	204.0
09	131.0	1.0	861.0	3.0
10	5.0	6.0	983.0	2.0
11	1.0	5.0	987.0	3.0
12	16.0	958.0	0.0	22.0
13	3.0	1.0	988.0	4.0
14	4.0	5.0	872.0	115.0
15	196.0	4.0	786.0	10.0
16	16.0	20.0	950.0	10.0
17	28.0	908.0	9.0	51.0
18	33.0	598.0	82.0	283.0
19	216.0	87.0	136.0	557.0

PFM

	A	C	G	T
01	0.153	0.335	0.394	0.118
02	0.172	0.296	0.459	0.073
03	0.139	0.307	0.463	0.091
04	0.093	0.24	0.524	0.143
05	0.159	0.297	0.422	0.122
06	0.357	0.177	0.292	0.174
07	0.256	0.088	0.623	0.032
08	0.096	0.002	0.697	0.205
09	0.132	0.001	0.864	0.003
10	0.005	0.006	0.987	0.002
11	0.001	0.005	0.991	0.003
12	0.016	0.962	0.0	0.022
13	0.003	0.001	0.992	0.004
14	0.004	0.005	0.876	0.115
15	0.197	0.004	0.789	0.01
16	0.016	0.02	0.954	0.01
17	0.028	0.912	0.009	0.051
18	0.033	0.6	0.082	0.284
19	0.217	0.087	0.137	0.559

PWM

	A	C	G	T
01	-0.489	0.292	0.451	-0.739
02	-0.373	0.168	0.604	-1.211
03	-0.585	0.205	0.613	-0.995
04	-0.973	-0.041	0.737	-0.556
05	-0.451	0.172	0.52	-0.706
06	0.355	-0.344	0.155	-0.361
07	0.024	-1.028	0.91	-2.006
08	-0.942	-4.209	1.021	-0.198
09	-0.636	-4.522	1.236	-3.971
10	-3.618	-3.48	1.368	-4.209
11	-4.522	-3.618	1.372	-3.971
12	-2.649	1.342	-4.979	-2.358
13	-3.971	-4.522	1.373	-3.779
14	-3.779	-3.618	1.248	-0.765
15	-0.237	-3.779	1.145	-3.063
16	-2.649	-2.446	1.334	-3.063
17	-2.132	1.289	-3.152	-1.559
18	-1.977	0.872	-1.097	0.127
19	-0.141	-1.039	-0.599	0.801

Standard thresholds

P-value	Threshold
0.001	1.06821
0.0005	2.47301
0.0001	5.42541