SP2.H12INVITRO.1.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SP2.H12INVITRO.1.P.D
Gene (human)	SP2 (GeneCards)
Gene synonyms (human)	KIAA0048
Gene (mouse)	Sp2
Gene synonyms (mouse)	Kiaa0048
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	D

Motif length	21
Consensus	vvnbnnvdRGGMKGRvvnnvv
GC content	68.62%
Information content (bits; total / per base)	9.513 / 0.453
Data sources	ChIP-Seq
Aligned words	864

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (33)	0.693	0.873	0.476	0.729	0.807	0.915	2.942	4.042	20.62	127.252

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	1.275	0.802	0.046	0.024

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Sp1-like {2.3.1.1} (TFClass)
TFClass ID	TFClass: 2.3.1.1.2
HGNC	HGNC:11207
MGI	MGI:1926162
EntrezGene (human)	GeneID:6668 (SSTAR profile)
EntrezGene (mouse)	GeneID:78912 (SSTAR profile)
UniProt ID (human)	SP2_HUMAN
UniProt ID (mouse)	SP2_MOUSE
UniProt AC (human)	Q02086 (TFClass)
UniProt AC (mouse)	Q9D2H6 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 0 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	SP2.H12INVITRO.1.P.D.pcm
PWM	SP2.H12INVITRO.1.P.D.pwm
PFM	SP2.H12INVITRO.1.P.D.pfm
Alignment	SP2.H12INVITRO.1.P.D.words.tsv
Threshold to P-value map	SP2.H12INVITRO.1.P.D.thr
Motif in other formats
JASPAR format	SP2.H12INVITRO.1.P.D_jaspar_format.txt
MEME format	SP2.H12INVITRO.1.P.D_meme_format.meme
Transfac format	SP2.H12INVITRO.1.P.D_transfac_format.txt
Homer format	SP2.H12INVITRO.1.P.D_homer_format_0.001.txt SP2.H12INVITRO.1.P.D_homer_format_0.0005.txt SP2.H12INVITRO.1.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	166.0	335.0	259.0	104.0
02	198.0	286.0	281.0	99.0
03	172.0	236.0	298.0	158.0
04	128.0	261.0	332.0	143.0
05	160.0	296.0	269.0	139.0
06	275.0	180.0	289.0	120.0
07	258.0	158.0	387.0	61.0
08	227.0	39.0	468.0	130.0
09	283.0	30.0	528.0	23.0
10	109.0	2.0	744.0	9.0
11	25.0	0.0	837.0	2.0
12	171.0	635.0	0.0	58.0
13	72.0	30.0	687.0	75.0
14	44.0	29.0	747.0	44.0
15	217.0	49.0	512.0	86.0
16	215.0	128.0	446.0	75.0
17	167.0	395.0	198.0	104.0
18	149.0	303.0	216.0	196.0
19	201.0	155.0	297.0	211.0
20	213.0	179.0	375.0	97.0
21	199.0	171.0	383.0	111.0

PFM

	A	C	G	T
01	0.192	0.388	0.3	0.12
02	0.229	0.331	0.325	0.115
03	0.199	0.273	0.345	0.183
04	0.148	0.302	0.384	0.166
05	0.185	0.343	0.311	0.161
06	0.318	0.208	0.334	0.139
07	0.299	0.183	0.448	0.071
08	0.263	0.045	0.542	0.15
09	0.328	0.035	0.611	0.027
10	0.126	0.002	0.861	0.01
11	0.029	0.0	0.969	0.002
12	0.198	0.735	0.0	0.067
13	0.083	0.035	0.795	0.087
14	0.051	0.034	0.865	0.051
15	0.251	0.057	0.593	0.1
16	0.249	0.148	0.516	0.087
17	0.193	0.457	0.229	0.12
18	0.172	0.351	0.25	0.227
19	0.233	0.179	0.344	0.244
20	0.247	0.207	0.434	0.112
21	0.23	0.198	0.443	0.128

PWM

	A	C	G	T
01	-0.261	0.436	0.18	-0.723
02	-0.086	0.279	0.261	-0.771
03	-0.226	0.088	0.32	-0.31
04	-0.518	0.188	0.427	-0.408
05	-0.297	0.313	0.218	-0.437
06	0.24	-0.181	0.289	-0.582
07	0.176	-0.31	0.58	-1.245
08	0.049	-1.677	0.769	-0.503
09	0.268	-1.927	0.889	-2.177
10	-0.676	-4.077	1.231	-3.014
11	-2.099	-4.858	1.349	-4.077
12	-0.232	1.073	-4.858	-1.294
13	-1.083	-1.927	1.152	-1.043
14	-1.561	-1.959	1.235	-1.561
15	0.005	-1.457	0.859	-0.909
16	-0.005	-0.518	0.721	-1.043
17	-0.255	0.6	-0.086	-0.723
18	-0.368	0.336	0.0	-0.096
19	-0.071	-0.329	0.316	-0.023
20	-0.014	-0.186	0.548	-0.791
21	-0.081	-0.232	0.569	-0.658

Standard thresholds

P-value	Threshold
0.001	4.84341
0.0005	5.62046
0.0001	7.19881