MotifSP1.H12INVIVO.0.P.B
Gene (human)SP1
(GeneCards)
Gene synonyms (human)TSFP1
Gene (mouse)Sp1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length14
ConsensusnRKGGGCGGGGCYd
GC content77.43%
Information content (bits; total / per base)15.859 / 1.133
Data sourcesChIP-Seq
Aligned words971

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 14 (91) 0.876 0.969 0.762 0.925 0.928 0.986 4.176 5.558 66.367 209.469
Mouse 10 (52) 0.898 0.958 0.815 0.905 0.899 0.963 4.034 4.554 68.678 176.745

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 3 experiments median 0.995 0.992 0.948 0.934 0.746 0.781
best 0.996 0.993 0.973 0.969 0.768 0.807
Methyl HT-SELEX, 1 experiments median 0.995 0.992 0.902 0.906 0.681 0.738
best 0.995 0.992 0.902 0.906 0.681 0.738
Non-Methyl HT-SELEX, 2 experiments median 0.99 0.983 0.96 0.951 0.757 0.794
best 0.996 0.993 0.973 0.969 0.768 0.807

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 1.205 0.43 0.024 0.017
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyThree-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamilySp1-like {2.3.1.1} (TFClass)
TFClass IDTFClass: 2.3.1.1.1
HGNCHGNC:11205
MGIMGI:98372
EntrezGene (human)GeneID:6667
(SSTAR profile)
EntrezGene (mouse)GeneID:20683
(SSTAR profile)
UniProt ID (human)SP1_HUMAN
UniProt ID (mouse)SP1_MOUSE
UniProt AC (human)P08047
(TFClass)
UniProt AC (mouse)O89090
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 14 human, 10 mouse
HT-SELEX 2
Methyl-HT-SELEX 1
PCM
ACGT
01369.0154.0218.0230.0
02263.048.0626.034.0
03116.04.0610.0241.0
04124.00.0844.03.0
050.01.0967.03.0
062.01.0965.03.0
0724.0891.00.056.0
084.04.0959.04.0
096.04.0753.0208.0
10149.04.0798.020.0
1162.013.0866.030.0
1239.0849.010.073.0
1358.0538.093.0282.0
14222.070.0236.0443.0
PFM
ACGT
010.380.1590.2250.237
020.2710.0490.6450.035
030.1190.0040.6280.248
040.1280.00.8690.003
050.00.0010.9960.003
060.0020.0010.9940.003
070.0250.9180.00.058
080.0040.0040.9880.004
090.0060.0040.7750.214
100.1530.0040.8220.021
110.0640.0130.8920.031
120.040.8740.010.075
130.060.5540.0960.29
140.2290.0720.2430.456
PWM
ACGT
010.416-0.451-0.107-0.054
020.08-1.5930.943-1.923
03-0.731-3.7550.917-0.007
04-0.665-4.9571.241-3.947
05-4.957-4.4991.377-3.947
06-4.185-4.4991.375-3.947
07-2.2521.295-4.957-1.443
08-3.755-3.7551.369-3.755
09-3.455-3.7551.127-0.153
10-0.484-3.7551.185-2.421
11-1.345-2.811.267-2.042
12-1.7921.247-3.038-1.185
13-1.4090.792-0.9480.149
14-0.089-1.226-0.0280.598
Standard thresholds
P-value Threshold
0.001 2.19451
0.0005 3.51691
0.0001 6.261315