MotifSOX9.H12INVIVO.2.S.B
Gene (human)SOX9
(GeneCards)
Gene synonyms (human)
Gene (mouse)Sox9
Gene synonyms (mouse)Sox-9
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length17
ConsensusnvWvAATTdCAGTbAKn
GC content33.04%
Information content (bits; total / per base)16.8 / 0.988
Data sourcesHT-SELEX
Aligned words5809

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.454 0.477 0.298 0.319 0.347 0.569 0.701 1.361 0 0
Mouse 6 (41) 0.468 0.504 0.315 0.341 0.544 0.606 1.18 1.363 0 0.959

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 4 experiments median 0.656 0.65 0.588 0.586 0.553 0.554
best 0.72 0.705 0.631 0.623 0.581 0.579

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.608 0.222 0.579 0.384
TF superclassOther all-alpha-helical DNA-binding domains {4} (TFClass)
TF classHigh-mobility group (HMG) domain factors {4.1} (TFClass)
TF familySOX-related {4.1.1} (TFClass)
TF subfamilyGroup E {4.1.1.5} (TFClass)
TFClass IDTFClass: 4.1.1.5.2
HGNCHGNC:11204
MGIMGI:98371
EntrezGene (human)GeneID:6662
(SSTAR profile)
EntrezGene (mouse)GeneID:20682
(SSTAR profile)
UniProt ID (human)SOX9_HUMAN
UniProt ID (mouse)SOX9_MOUSE
UniProt AC (human)P48436
(TFClass)
UniProt AC (mouse)Q04887
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 6 mouse
HT-SELEX 4
Methyl-HT-SELEX 0
PCM
ACGT
012117.01023.01236.01433.0
023507.0883.0743.0676.0
031489.0185.0265.03870.0
041425.02112.02018.0254.0
055613.033.021.0142.0
065256.029.053.0471.0
07182.038.0273.05316.0
0823.029.0753.05004.0
09658.0592.02604.01955.0
106.05138.08.0657.0
115741.016.010.042.0
122.015.05591.0201.0
137.020.020.05762.0
14142.02301.02290.01076.0
154183.018.038.01570.0
16327.75840.75928.753711.75
171810.75941.751565.751490.75
PFM
ACGT
010.3640.1760.2130.247
020.6040.1520.1280.116
030.2560.0320.0460.666
040.2450.3640.3470.044
050.9660.0060.0040.024
060.9050.0050.0090.081
070.0310.0070.0470.915
080.0040.0050.130.861
090.1130.1020.4480.337
100.0010.8840.0010.113
110.9880.0030.0020.007
120.00.0030.9620.035
130.0010.0030.0030.992
140.0240.3960.3940.185
150.720.0030.0070.27
160.0560.1450.160.639
170.3120.1620.270.257
PWM
ACGT
010.376-0.35-0.161-0.013
020.881-0.497-0.669-0.763
030.025-2.05-1.6940.979
04-0.0190.3740.329-1.737
051.351-3.722-4.14-2.311
061.285-3.843-3.272-1.123
07-2.067-3.589-1.6651.297
08-4.057-3.843-0.6551.236
09-0.79-0.8950.5830.297
10-5.1821.262-4.963-0.791
111.373-4.383-4.784-3.494
12-5.855-4.4391.347-1.968
13-5.067-4.184-4.1841.377
14-2.3110.460.455-0.299
151.057-4.278-3.5890.078
16-1.484-0.545-0.4460.937
170.22-0.4320.0750.026
Standard thresholds
P-value Threshold
0.001 1.34821
0.0005 2.77391
0.0001 5.74266