MotifSOX9.H12CORE.1.PS.A
Gene (human)SOX9
(GeneCards)
Gene synonyms (human)
Gene (mouse)Sox9
Gene synonyms (mouse)Sox-9
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length10
ConsensusnbhATTGTdn
GC content34.56%
Information content (bits; total / per base)10.045 / 1.004
Data sourcesChIP-Seq + HT-SELEX
Aligned words9295

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.539 0.579 0.397 0.449 0.402 0.53 0.983 1.321 17.244 25.092
Mouse 6 (41) 0.622 0.721 0.455 0.563 0.59 0.718 1.461 1.977 50.208 230.237

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 4 experiments median 0.734 0.705 0.665 0.652 0.593 0.597
best 0.91 0.878 0.825 0.783 0.749 0.716

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.743 0.438 0.737 0.633
TF superclassOther all-alpha-helical DNA-binding domains {4} (TFClass)
TF classHigh-mobility group (HMG) domain factors {4.1} (TFClass)
TF familySOX-related {4.1.1} (TFClass)
TF subfamilyGroup E {4.1.1.5} (TFClass)
TFClass IDTFClass: 4.1.1.5.2
HGNCHGNC:11204
MGIMGI:98371
EntrezGene (human)GeneID:6662
(SSTAR profile)
EntrezGene (mouse)GeneID:20682
(SSTAR profile)
UniProt ID (human)SOX9_HUMAN
UniProt ID (mouse)SOX9_MOUSE
UniProt AC (human)P48436
(TFClass)
UniProt AC (mouse)Q04887
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 6 mouse
HT-SELEX 4
Methyl-HT-SELEX 0
PCM
ACGT
012027.02281.02356.02631.0
02910.753687.752326.752369.75
031160.04059.0625.03451.0
049029.020.044.0202.0
050.02.04.09289.0
060.00.00.09295.0
0737.033.09225.00.0
08798.016.013.08468.0
091341.01262.01673.05019.0
101684.52841.51650.53118.5
PFM
ACGT
010.2180.2450.2530.283
020.0980.3970.250.255
030.1250.4370.0670.371
040.9710.0020.0050.022
050.00.00.00.999
060.00.00.01.0
070.0040.0040.9920.0
080.0860.0020.0010.911
090.1440.1360.180.54
100.1810.3060.1780.336
PWM
ACGT
01-0.136-0.0190.0140.124
02-0.9350.4610.0010.02
03-0.6940.557-1.3110.395
041.357-4.648-3.917-2.432
05-6.926-6.297-5.9141.385
06-6.926-6.926-6.9261.386
07-4.081-4.1881.378-6.926
08-1.067-4.846-5.0251.292
09-0.549-0.61-0.3280.77
10-0.3210.201-0.3420.294
Standard thresholds
P-value Threshold
0.001 4.971435
0.0005 6.24514
0.0001 7.62301