| Motif | SOX7.H12INVIVO.1.SM.B |
| Gene (human) | SOX7 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Sox7 |
| Gene synonyms (mouse) | Sox-7 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | B |
| Motif | SOX7.H12INVIVO.1.SM.B |
| Gene (human) | SOX7 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Sox7 |
| Gene synonyms (mouse) | Sox-7 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | B |
| Motif length | 19 |
| Consensus | nvvMMAWWdnCATTGTbhn |
| GC content | 34.85% |
| Information content (bits; total / per base) | 15.627 / 0.822 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 2480 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mouse | 1 (5) | 0.698 | 0.742 | 0.536 | 0.591 | 0.643 | 0.669 | 1.609 | 1.763 | 57.0 | 119.328 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 3 experiments | median | 0.999 | 0.999 | 0.992 | 0.989 | 0.941 | 0.935 |
| best | 1.0 | 1.0 | 0.996 | 0.995 | 0.942 | 0.94 | |
| Methyl HT-SELEX, 1 experiments | median | 1.0 | 1.0 | 0.996 | 0.995 | 0.942 | 0.94 |
| best | 1.0 | 1.0 | 0.996 | 0.995 | 0.942 | 0.94 | |
| Non-Methyl HT-SELEX, 2 experiments | median | 0.821 | 0.822 | 0.786 | 0.785 | 0.744 | 0.743 |
| best | 0.999 | 0.999 | 0.992 | 0.989 | 0.941 | 0.935 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.703 | 0.533 | 0.569 | 0.374 |
| batch 2 | 0.834 | 0.692 | 0.792 | 0.405 |
| TF superclass | Other all-alpha-helical DNA-binding domains {4} (TFClass) |
| TF class | High-mobility group (HMG) domain factors {4.1} (TFClass) |
| TF family | SOX-related {4.1.1} (TFClass) |
| TF subfamily | Group F {4.1.1.6} (TFClass) |
| TFClass ID | TFClass: 4.1.1.6.1 |
| HGNC | HGNC:18196 |
| MGI | MGI:98369 |
| EntrezGene (human) | GeneID:83595 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:20680 (SSTAR profile) |
| UniProt ID (human) | SOX7_HUMAN |
| UniProt ID (mouse) | SOX7_MOUSE |
| UniProt AC (human) | Q9BT81 (TFClass) |
| UniProt AC (mouse) | P40646 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 1 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 1 |
| PCM | SOX7.H12INVIVO.1.SM.B.pcm |
| PWM | SOX7.H12INVIVO.1.SM.B.pwm |
| PFM | SOX7.H12INVIVO.1.SM.B.pfm |
| Alignment | SOX7.H12INVIVO.1.SM.B.words.tsv |
| Threshold to P-value map | SOX7.H12INVIVO.1.SM.B.thr |
| Motif in other formats | |
| JASPAR format | SOX7.H12INVIVO.1.SM.B_jaspar_format.txt |
| MEME format | SOX7.H12INVIVO.1.SM.B_meme_format.meme |
| Transfac format | SOX7.H12INVIVO.1.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 716.0 | 547.0 | 763.0 | 454.0 |
| 02 | 966.5 | 426.5 | 699.5 | 387.5 |
| 03 | 1377.0 | 431.0 | 451.0 | 221.0 |
| 04 | 1657.0 | 562.0 | 60.0 | 201.0 |
| 05 | 803.0 | 1425.0 | 97.0 | 155.0 |
| 06 | 2006.0 | 95.0 | 73.0 | 306.0 |
| 07 | 1558.0 | 121.0 | 111.0 | 690.0 |
| 08 | 406.0 | 130.0 | 254.0 | 1690.0 |
| 09 | 736.0 | 143.0 | 280.0 | 1321.0 |
| 10 | 448.0 | 957.0 | 593.0 | 482.0 |
| 11 | 566.0 | 1834.0 | 0.0 | 80.0 |
| 12 | 2480.0 | 0.0 | 0.0 | 0.0 |
| 13 | 3.0 | 2.0 | 11.0 | 2464.0 |
| 14 | 0.0 | 0.0 | 0.0 | 2480.0 |
| 15 | 4.0 | 14.0 | 2461.0 | 1.0 |
| 16 | 84.0 | 18.0 | 10.0 | 2368.0 |
| 17 | 231.0 | 691.0 | 273.0 | 1285.0 |
| 18 | 562.0 | 1076.0 | 405.0 | 437.0 |
| 19 | 537.25 | 878.25 | 527.25 | 537.25 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.289 | 0.221 | 0.308 | 0.183 |
| 02 | 0.39 | 0.172 | 0.282 | 0.156 |
| 03 | 0.555 | 0.174 | 0.182 | 0.089 |
| 04 | 0.668 | 0.227 | 0.024 | 0.081 |
| 05 | 0.324 | 0.575 | 0.039 | 0.063 |
| 06 | 0.809 | 0.038 | 0.029 | 0.123 |
| 07 | 0.628 | 0.049 | 0.045 | 0.278 |
| 08 | 0.164 | 0.052 | 0.102 | 0.681 |
| 09 | 0.297 | 0.058 | 0.113 | 0.533 |
| 10 | 0.181 | 0.386 | 0.239 | 0.194 |
| 11 | 0.228 | 0.74 | 0.0 | 0.032 |
| 12 | 1.0 | 0.0 | 0.0 | 0.0 |
| 13 | 0.001 | 0.001 | 0.004 | 0.994 |
| 14 | 0.0 | 0.0 | 0.0 | 1.0 |
| 15 | 0.002 | 0.006 | 0.992 | 0.0 |
| 16 | 0.034 | 0.007 | 0.004 | 0.955 |
| 17 | 0.093 | 0.279 | 0.11 | 0.518 |
| 18 | 0.227 | 0.434 | 0.163 | 0.176 |
| 19 | 0.217 | 0.354 | 0.213 | 0.217 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.144 | -0.125 | 0.207 | -0.31 |
| 02 | 0.443 | -0.373 | 0.12 | -0.468 |
| 03 | 0.796 | -0.362 | -0.317 | -1.026 |
| 04 | 0.981 | -0.098 | -2.306 | -1.12 |
| 05 | 0.258 | 0.83 | -1.838 | -1.377 |
| 06 | 1.172 | -1.859 | -2.116 | -0.703 |
| 07 | 0.92 | -1.621 | -1.706 | 0.107 |
| 08 | -0.422 | -1.55 | -0.888 | 1.001 |
| 09 | 0.171 | -1.456 | -0.791 | 0.755 |
| 10 | -0.324 | 0.433 | -0.044 | -0.251 |
| 11 | -0.091 | 1.082 | -5.763 | -2.027 |
| 12 | 1.384 | -5.763 | -5.763 | -5.763 |
| 13 | -4.833 | -5.058 | -3.871 | 1.377 |
| 14 | -5.763 | -5.763 | -5.763 | 1.384 |
| 15 | -4.649 | -3.663 | 1.376 | -5.35 |
| 16 | -1.979 | -3.439 | -3.952 | 1.338 |
| 17 | -0.982 | 0.108 | -0.816 | 0.727 |
| 18 | -0.098 | 0.55 | -0.424 | -0.348 |
| 19 | -0.143 | 0.347 | -0.161 | -0.143 |
| P-value | Threshold |
|---|---|
| 0.001 | 1.92241 |
| 0.0005 | 3.36616 |
| 0.0001 | 6.32731 |