MotifSOX7.H12INVIVO.0.PS.A
Gene (human)SOX7
(GeneCards)
Gene synonyms (human)
Gene (mouse)Sox7
Gene synonyms (mouse)Sox-7
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length9
ConsensusYCATTGTYY
GC content39.18%
Information content (bits; total / per base)11.761 / 1.307
Data sourcesChIP-Seq + HT-SELEX
Aligned words985

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (5) 0.813 0.869 0.78 0.845 0.814 0.857 3.166 3.495 168.481 347.921

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 3 experiments median 0.959 0.936 0.912 0.883 0.801 0.793
best 0.966 0.946 0.922 0.896 0.81 0.793
Methyl HT-SELEX, 1 experiments median 0.966 0.946 0.922 0.896 0.801 0.793
best 0.966 0.946 0.922 0.896 0.801 0.793
Non-Methyl HT-SELEX, 2 experiments median 0.772 0.748 0.733 0.711 0.672 0.66
best 0.959 0.936 0.912 0.883 0.81 0.793

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.67 0.52 0.527 0.313
batch 2 0.722 0.597 0.668 0.36
TF superclassOther all-alpha-helical DNA-binding domains {4} (TFClass)
TF classHigh-mobility group (HMG) domain factors {4.1} (TFClass)
TF familySOX-related {4.1.1} (TFClass)
TF subfamilyGroup F {4.1.1.6} (TFClass)
TFClass IDTFClass: 4.1.1.6.1
HGNCHGNC:18196
MGIMGI:98369
EntrezGene (human)GeneID:83595
(SSTAR profile)
EntrezGene (mouse)GeneID:20680
(SSTAR profile)
UniProt ID (human)SOX7_HUMAN
UniProt ID (mouse)SOX7_MOUSE
UniProt AC (human)Q9BT81
(TFClass)
UniProt AC (mouse)P40646
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 2
Methyl-HT-SELEX 1
PCM
ACGT
0117.0745.088.0135.0
0216.0733.09.0227.0
03880.017.03.085.0
045.08.018.0954.0
059.05.02.0969.0
069.017.0883.076.0
076.08.09.0962.0
0814.0242.036.0693.0
0933.0611.039.0302.0
PFM
ACGT
010.0170.7560.0890.137
020.0160.7440.0090.23
030.8930.0170.0030.086
040.0050.0080.0180.969
050.0090.0050.0020.984
060.0090.0170.8960.077
070.0060.0080.0090.977
080.0140.2460.0370.704
090.0340.620.040.307
PWM
ACGT
01-2.5841.102-1.017-0.595
02-2.6381.086-3.141-0.081
031.269-2.584-3.961-1.051
04-3.608-3.239-2.5321.349
05-3.141-3.608-4.1991.365
06-3.141-2.5841.272-1.16
07-3.469-3.239-3.1411.357
08-2.758-0.017-1.8831.03
09-1.9660.905-1.8070.203
Standard thresholds
P-value Threshold
0.001 4.118705
0.0005 5.17094
0.0001 7.21355