MotifSOX7.H12INVITRO.1.SM.B
Gene (human)SOX7
(GeneCards)
Gene synonyms (human)
Gene (mouse)Sox7
Gene synonyms (mouse)Sox-7
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length17
ConsensusnvMMAWWdnCATTGTbn
GC content32.86%
Information content (bits; total / per base)15.5 / 0.912
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9938

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (5) 0.663 0.714 0.498 0.55 0.616 0.65 1.486 1.648 43.602 90.187

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 3 experiments median 0.999 0.999 0.994 0.992 0.947 0.942
best 1.0 1.0 0.997 0.996 0.949 0.947
Methyl HT-SELEX, 1 experiments median 1.0 1.0 0.997 0.996 0.949 0.947
best 1.0 1.0 0.997 0.996 0.949 0.947
Non-Methyl HT-SELEX, 2 experiments median 0.818 0.821 0.784 0.785 0.745 0.745
best 0.999 0.999 0.994 0.992 0.947 0.942

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.715 0.529 0.585 0.415
batch 2 0.872 0.694 0.861 0.36
TF superclassOther all-alpha-helical DNA-binding domains {4} (TFClass)
TF classHigh-mobility group (HMG) domain factors {4.1} (TFClass)
TF familySOX-related {4.1.1} (TFClass)
TF subfamilyGroup F {4.1.1.6} (TFClass)
TFClass IDTFClass: 4.1.1.6.1
HGNCHGNC:18196
MGIMGI:98369
EntrezGene (human)GeneID:83595
(SSTAR profile)
EntrezGene (mouse)GeneID:20680
(SSTAR profile)
UniProt ID (human)SOX7_HUMAN
UniProt ID (mouse)SOX7_MOUSE
UniProt AC (human)Q9BT81
(TFClass)
UniProt AC (mouse)P40646
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 2
Methyl-HT-SELEX 1
PCM
ACGT
013627.252169.252566.251575.25
025137.752064.751748.75986.75
036824.02141.0270.0703.0
042904.06149.0396.0489.0
058425.0222.0218.01073.0
066663.0321.0335.02619.0
071064.0497.0898.07479.0
082518.0726.01248.05446.0
092041.02810.02778.02309.0
10638.07958.03.01339.0
119936.00.00.02.0
121.00.0166.09771.0
130.00.04.09934.0
1415.0243.09680.00.0
15565.089.071.09213.0
161085.752524.751633.754693.75
172208.753593.751984.752150.75
PFM
ACGT
010.3650.2180.2580.159
020.5170.2080.1760.099
030.6870.2150.0270.071
040.2920.6190.040.049
050.8480.0220.0220.108
060.670.0320.0340.264
070.1070.050.090.753
080.2530.0730.1260.548
090.2050.2830.280.232
100.0640.8010.00.135
111.00.00.00.0
120.00.00.0170.983
130.00.00.01.0
140.0020.0240.9740.0
150.0570.0090.0070.927
160.1090.2540.1640.472
170.2220.3620.20.216
PWM
ACGT
010.378-0.1360.032-0.455
020.726-0.185-0.351-0.922
031.01-0.149-2.212-1.26
040.1560.906-1.832-1.622
051.22-2.406-2.424-0.838
060.986-2.04-1.9980.053
07-0.847-1.606-1.0161.101
080.013-1.228-0.6880.784
09-0.1960.1230.112-0.073
10-1.3571.163-6.151-0.617
111.385-6.985-6.985-6.36
12-6.625-6.985-2.6931.369
13-6.985-6.985-5.9781.385
14-4.968-2.3161.359-6.985
15-1.478-3.305-3.5241.31
16-0.8270.016-0.4190.636
17-0.1180.369-0.224-0.144
Standard thresholds
P-value Threshold
0.001 1.95306
0.0005 3.43941
0.0001 6.36481