MotifSOX30.H12CORE.0.P.C
Gene (human)SOX30
(GeneCards)
Gene synonyms (human)
Gene (mouse)Sox30
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
C
Motif length11
ConsensusnSCWYTGTSWY
GC content51.94%
Information content (bits; total / per base)9.806 / 0.891
Data sourcesChIP-Seq
Aligned words227

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (7) 0.577 0.659 0.468 0.556 0.63 0.757 2.087 3.249 10.222 12.0

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 3 experiments median 0.748 0.677 0.695 0.641 0.634 0.604
best 0.782 0.715 0.708 0.662 0.635 0.613
Methyl HT-SELEX, 1 experiments median 0.782 0.715 0.708 0.662 0.635 0.613
best 0.782 0.715 0.708 0.662 0.635 0.613
Non-Methyl HT-SELEX, 2 experiments median 0.647 0.602 0.614 0.581 0.578 0.56
best 0.748 0.677 0.695 0.641 0.634 0.604

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.633 0.071 0.578 0.459
TF superclassOther all-alpha-helical DNA-binding domains {4} (TFClass)
TF classHigh-mobility group (HMG) domain factors {4.1} (TFClass)
TF familySOX-related {4.1.1} (TFClass)
TF subfamilyGroup H {4.1.1.8} (TFClass)
TFClass IDTFClass: 4.1.1.8.1
HGNCHGNC:30635
MGIMGI:1341157
EntrezGene (human)GeneID:11063
(SSTAR profile)
EntrezGene (mouse)GeneID:214105
(SSTAR profile)
UniProt ID (human)SOX30_HUMAN
UniProt ID (mouse)SOX30_MOUSE
UniProt AC (human)O94993
(TFClass)
UniProt AC (mouse)Q8CGW4
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 2
Methyl-HT-SELEX 1
PCM
ACGT
0140.056.044.087.0
026.0141.063.017.0
036.0199.014.08.0
04125.011.012.079.0
051.098.03.0125.0
063.06.05.0213.0
078.027.0187.05.0
081.04.03.0219.0
0914.028.0169.016.0
10149.022.022.034.0
115.0148.035.039.0
PFM
ACGT
010.1760.2470.1940.383
020.0260.6210.2780.075
030.0260.8770.0620.035
040.5510.0480.0530.348
050.0040.4320.0130.551
060.0130.0260.0220.938
070.0350.1190.8240.022
080.0040.0180.0130.965
090.0620.1230.7440.07
100.6560.0970.0970.15
110.0220.6520.1540.172
PWM
ACGT
01-0.34-0.013-0.2480.419
02-2.0670.8960.102-1.152
03-2.0671.238-1.331-1.826
040.777-1.548-1.470.324
05-3.2050.536-2.5910.777
06-2.591-2.067-2.2131.305
07-1.826-0.7171.176-2.213
08-3.205-2.384-2.5911.333
09-1.331-0.6831.076-1.208
100.951-0.911-0.911-0.497
11-2.2130.944-0.469-0.365
Standard thresholds
P-value Threshold
0.001 4.81502
0.0005 5.60827
0.0001 7.2004