MotifSOX21.H12INVIVO.0.S.D
Gene (human)SOX21
(GeneCards)
Gene synonyms (human)SOX25, SOXA
Gene (mouse)Sox21
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length18
ConsensusnhhvMhYdhCATTShbhn
GC content37.84%
Information content (bits; total / per base)10.0 / 0.556
Data sourcesHT-SELEX
Aligned words7944

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.818 0.805 0.703 0.696 0.624 0.627
best 0.925 0.918 0.772 0.771 0.662 0.673
TF superclassOther all-alpha-helical DNA-binding domains {4} (TFClass)
TF classHigh-mobility group (HMG) domain factors {4.1} (TFClass)
TF familySOX-related {4.1.1} (TFClass)
TF subfamilyGroup B {4.1.1.2} (TFClass)
TFClass IDTFClass: 4.1.1.2.5
HGNCHGNC:11197
MGIMGI:2654070
EntrezGene (human)GeneID:11166
(SSTAR profile)
EntrezGene (mouse)GeneID:223227
(SSTAR profile)
UniProt ID (human)SOX21_HUMAN
UniProt ID (mouse)SOX21_MOUSE
UniProt AC (human)Q9Y651
(TFClass)
UniProt AC (mouse)Q811W0
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
012094.51902.51655.52291.5
023305.01726.01222.01691.0
033610.01391.0747.02196.0
041163.04241.01393.01147.0
054879.01454.0640.0971.0
063271.02456.0679.01538.0
07825.01015.0726.05378.0
083489.01118.01484.01853.0
092132.02735.0896.02181.0
101079.06421.011.0433.0
117479.0391.042.032.0
121.0243.020.07680.0
131.068.06.07869.0
14563.02838.04498.045.0
151882.01355.0511.04196.0
16791.01722.0939.04492.0
171497.02761.01096.02590.0
181866.252247.251463.252367.25
PFM
ACGT
010.2640.2390.2080.288
020.4160.2170.1540.213
030.4540.1750.0940.276
040.1460.5340.1750.144
050.6140.1830.0810.122
060.4120.3090.0850.194
070.1040.1280.0910.677
080.4390.1410.1870.233
090.2680.3440.1130.275
100.1360.8080.0010.055
110.9410.0490.0050.004
120.00.0310.0030.967
130.00.0090.0010.991
140.0710.3570.5660.006
150.2370.1710.0640.528
160.10.2170.1180.565
170.1880.3480.1380.326
180.2350.2830.1840.298
PWM
ACGT
010.053-0.043-0.1820.143
020.509-0.14-0.485-0.161
030.597-0.356-0.9760.1
04-0.5340.758-0.354-0.548
050.898-0.311-1.13-0.714
060.4990.212-1.071-0.255
07-0.877-0.67-1.0040.995
080.563-0.574-0.291-0.069
090.0710.32-0.7950.094
10-0.6091.173-5.011-1.519
111.325-1.621-3.805-4.061
12-6.418-2.093-4.4931.352
13-6.418-3.343-5.4851.376
14-1.2580.3570.817-3.74
15-0.054-0.382-1.3540.747
16-0.919-0.142-0.7480.816
17-0.2820.329-0.5940.265
18-0.0620.123-0.3050.175
Standard thresholds
P-value Threshold
0.001 4.83291
0.0005 5.67886
0.0001 7.31251