SOX21.H12CORE.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SOX21.H12CORE.0.S.B
Gene (human)	SOX21 (GeneCards)
Gene synonyms (human)	SOX25, SOXA
Gene (mouse)	Sox21
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	18
Consensus	nhhvMhYdhCATTShbhn
GC content	37.84%
Information content (bits; total / per base)	10.0 / 0.556
Data sources	HT-SELEX
Aligned words	7944

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.818	0.805	0.703	0.696	0.624	0.627
Non-Methyl HT-SELEX, 2 experiments	best	0.925	0.918	0.772	0.771	0.662	0.673

TF superclass	Other all-alpha-helical DNA-binding domains {4} (TFClass)
TF class	High-mobility group (HMG) domain factors {4.1} (TFClass)
TF family	SOX-related {4.1.1} (TFClass)
TF subfamily	Group B {4.1.1.2} (TFClass)
TFClass ID	TFClass: 4.1.1.2.5
HGNC	HGNC:11197
MGI	MGI:2654070
EntrezGene (human)	GeneID:11166 (SSTAR profile)
EntrezGene (mouse)	GeneID:223227 (SSTAR profile)
UniProt ID (human)	SOX21_HUMAN
UniProt ID (mouse)	SOX21_MOUSE
UniProt AC (human)	Q9Y651 (TFClass)
UniProt AC (mouse)	Q811W0 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	SOX21.H12CORE.0.S.B.pcm
PWM	SOX21.H12CORE.0.S.B.pwm
PFM	SOX21.H12CORE.0.S.B.pfm
Alignment	SOX21.H12CORE.0.S.B.words.tsv
Threshold to P-value map	SOX21.H12CORE.0.S.B.thr
Motif in other formats
JASPAR format	SOX21.H12CORE.0.S.B_jaspar_format.txt
MEME format	SOX21.H12CORE.0.S.B_meme_format.meme
Transfac format	SOX21.H12CORE.0.S.B_transfac_format.txt
Homer format	SOX21.H12CORE.0.S.B_homer_format_0.001.txt SOX21.H12CORE.0.S.B_homer_format_0.0005.txt SOX21.H12CORE.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2094.5	1902.5	1655.5	2291.5
02	3305.0	1726.0	1222.0	1691.0
03	3610.0	1391.0	747.0	2196.0
04	1163.0	4241.0	1393.0	1147.0
05	4879.0	1454.0	640.0	971.0
06	3271.0	2456.0	679.0	1538.0
07	825.0	1015.0	726.0	5378.0
08	3489.0	1118.0	1484.0	1853.0
09	2132.0	2735.0	896.0	2181.0
10	1079.0	6421.0	11.0	433.0
11	7479.0	391.0	42.0	32.0
12	1.0	243.0	20.0	7680.0
13	1.0	68.0	6.0	7869.0
14	563.0	2838.0	4498.0	45.0
15	1882.0	1355.0	511.0	4196.0
16	791.0	1722.0	939.0	4492.0
17	1497.0	2761.0	1096.0	2590.0
18	1866.25	2247.25	1463.25	2367.25

PFM

	A	C	G	T
01	0.264	0.239	0.208	0.288
02	0.416	0.217	0.154	0.213
03	0.454	0.175	0.094	0.276
04	0.146	0.534	0.175	0.144
05	0.614	0.183	0.081	0.122
06	0.412	0.309	0.085	0.194
07	0.104	0.128	0.091	0.677
08	0.439	0.141	0.187	0.233
09	0.268	0.344	0.113	0.275
10	0.136	0.808	0.001	0.055
11	0.941	0.049	0.005	0.004
12	0.0	0.031	0.003	0.967
13	0.0	0.009	0.001	0.991
14	0.071	0.357	0.566	0.006
15	0.237	0.171	0.064	0.528
16	0.1	0.217	0.118	0.565
17	0.188	0.348	0.138	0.326
18	0.235	0.283	0.184	0.298

PWM

	A	C	G	T
01	0.053	-0.043	-0.182	0.143
02	0.509	-0.14	-0.485	-0.161
03	0.597	-0.356	-0.976	0.1
04	-0.534	0.758	-0.354	-0.548
05	0.898	-0.311	-1.13	-0.714
06	0.499	0.212	-1.071	-0.255
07	-0.877	-0.67	-1.004	0.995
08	0.563	-0.574	-0.291	-0.069
09	0.071	0.32	-0.795	0.094
10	-0.609	1.173	-5.011	-1.519
11	1.325	-1.621	-3.805	-4.061
12	-6.418	-2.093	-4.493	1.352
13	-6.418	-3.343	-5.485	1.376
14	-1.258	0.357	0.817	-3.74
15	-0.054	-0.382	-1.354	0.747
16	-0.919	-0.142	-0.748	0.816
17	-0.282	0.329	-0.594	0.265
18	-0.062	0.123	-0.305	0.175

Standard thresholds

P-value	Threshold
0.001	4.83291
0.0005	5.67886
0.0001	7.31251