MotifSOX18.H12CORE.0.SM.B
Gene (human)SOX18
(GeneCards)
Gene synonyms (human)
Gene (mouse)Sox18
Gene synonyms (mouse)Sox-18
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length9
ConsensusnbYATTGTn
GC content38.39%
Information content (bits; total / per base)10.796 / 1.2
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words7556

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.766 0.734 0.728 0.698 0.658 0.645
best 0.939 0.902 0.887 0.849 0.776 0.757
Methyl HT-SELEX, 1 experiments median 0.939 0.902 0.887 0.849 0.776 0.757
best 0.939 0.902 0.887 0.849 0.776 0.757
Non-Methyl HT-SELEX, 1 experiments median 0.593 0.565 0.569 0.547 0.541 0.532
best 0.593 0.565 0.569 0.547 0.541 0.532

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.659 0.231 0.664 0.451
TF superclassOther all-alpha-helical DNA-binding domains {4} (TFClass)
TF classHigh-mobility group (HMG) domain factors {4.1} (TFClass)
TF familySOX-related {4.1.1} (TFClass)
TF subfamilyGroup F {4.1.1.6} (TFClass)
TFClass IDTFClass: 4.1.1.6.3
HGNCHGNC:11194
MGIMGI:103559
EntrezGene (human)GeneID:54345
(SSTAR profile)
EntrezGene (mouse)GeneID:20672
(SSTAR profile)
UniProt ID (human)SOX18_HUMAN
UniProt ID (mouse)SOX18_MOUSE
UniProt AC (human)P35713
(TFClass)
UniProt AC (mouse)P43680
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
011457.51823.52469.51805.5
02652.02583.03146.01175.0
03680.04537.0259.02080.0
047556.00.00.00.0
050.00.00.07556.0
060.00.00.07556.0
070.00.07556.00.0
0831.037.00.07488.0
091137.751903.751794.752719.75
PFM
ACGT
010.1930.2410.3270.239
020.0860.3420.4160.156
030.090.60.0340.275
041.00.00.00.0
050.00.00.01.0
060.00.00.01.0
070.00.01.00.0
080.0040.0050.00.991
090.1510.2520.2380.36
PWM
ACGT
01-0.259-0.0350.268-0.045
02-1.0620.3130.51-0.474
03-1.020.876-1.980.096
041.385-6.742-6.742-6.742
05-6.742-6.742-6.7421.385
06-6.742-6.742-6.7421.385
07-6.742-6.7421.385-6.742
08-4.041-3.875-6.7421.376
09-0.5060.008-0.0510.364
Standard thresholds
P-value Threshold
0.001 3.22982
0.0005 6.164525
0.0001 7.86662