| Motif | SOX18.H12CORE.0.SM.B |
| Gene (human) | SOX18 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Sox18 |
| Gene synonyms (mouse) | Sox-18 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | SOX18.H12CORE.0.SM.B |
| Gene (human) | SOX18 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Sox18 |
| Gene synonyms (mouse) | Sox-18 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 9 |
| Consensus | nbYATTGTn |
| GC content | 38.39% |
| Information content (bits; total / per base) | 10.796 / 1.2 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 7556 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.766 | 0.734 | 0.728 | 0.698 | 0.658 | 0.645 |
| best | 0.939 | 0.902 | 0.887 | 0.849 | 0.776 | 0.757 | |
| Methyl HT-SELEX, 1 experiments | median | 0.939 | 0.902 | 0.887 | 0.849 | 0.776 | 0.757 |
| best | 0.939 | 0.902 | 0.887 | 0.849 | 0.776 | 0.757 | |
| Non-Methyl HT-SELEX, 1 experiments | median | 0.593 | 0.565 | 0.569 | 0.547 | 0.541 | 0.532 |
| best | 0.593 | 0.565 | 0.569 | 0.547 | 0.541 | 0.532 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.659 | 0.231 | 0.664 | 0.451 |
| TF superclass | Other all-alpha-helical DNA-binding domains {4} (TFClass) |
| TF class | High-mobility group (HMG) domain factors {4.1} (TFClass) |
| TF family | SOX-related {4.1.1} (TFClass) |
| TF subfamily | Group F {4.1.1.6} (TFClass) |
| TFClass ID | TFClass: 4.1.1.6.3 |
| HGNC | HGNC:11194 |
| MGI | MGI:103559 |
| EntrezGene (human) | GeneID:54345 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:20672 (SSTAR profile) |
| UniProt ID (human) | SOX18_HUMAN |
| UniProt ID (mouse) | SOX18_MOUSE |
| UniProt AC (human) | P35713 (TFClass) |
| UniProt AC (mouse) | P43680 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 1 |
| PCM | SOX18.H12CORE.0.SM.B.pcm |
| PWM | SOX18.H12CORE.0.SM.B.pwm |
| PFM | SOX18.H12CORE.0.SM.B.pfm |
| Alignment | SOX18.H12CORE.0.SM.B.words.tsv |
| Threshold to P-value map | SOX18.H12CORE.0.SM.B.thr |
| Motif in other formats | |
| JASPAR format | SOX18.H12CORE.0.SM.B_jaspar_format.txt |
| MEME format | SOX18.H12CORE.0.SM.B_meme_format.meme |
| Transfac format | SOX18.H12CORE.0.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1457.5 | 1823.5 | 2469.5 | 1805.5 |
| 02 | 652.0 | 2583.0 | 3146.0 | 1175.0 |
| 03 | 680.0 | 4537.0 | 259.0 | 2080.0 |
| 04 | 7556.0 | 0.0 | 0.0 | 0.0 |
| 05 | 0.0 | 0.0 | 0.0 | 7556.0 |
| 06 | 0.0 | 0.0 | 0.0 | 7556.0 |
| 07 | 0.0 | 0.0 | 7556.0 | 0.0 |
| 08 | 31.0 | 37.0 | 0.0 | 7488.0 |
| 09 | 1137.75 | 1903.75 | 1794.75 | 2719.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.193 | 0.241 | 0.327 | 0.239 |
| 02 | 0.086 | 0.342 | 0.416 | 0.156 |
| 03 | 0.09 | 0.6 | 0.034 | 0.275 |
| 04 | 1.0 | 0.0 | 0.0 | 0.0 |
| 05 | 0.0 | 0.0 | 0.0 | 1.0 |
| 06 | 0.0 | 0.0 | 0.0 | 1.0 |
| 07 | 0.0 | 0.0 | 1.0 | 0.0 |
| 08 | 0.004 | 0.005 | 0.0 | 0.991 |
| 09 | 0.151 | 0.252 | 0.238 | 0.36 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.259 | -0.035 | 0.268 | -0.045 |
| 02 | -1.062 | 0.313 | 0.51 | -0.474 |
| 03 | -1.02 | 0.876 | -1.98 | 0.096 |
| 04 | 1.385 | -6.742 | -6.742 | -6.742 |
| 05 | -6.742 | -6.742 | -6.742 | 1.385 |
| 06 | -6.742 | -6.742 | -6.742 | 1.385 |
| 07 | -6.742 | -6.742 | 1.385 | -6.742 |
| 08 | -4.041 | -3.875 | -6.742 | 1.376 |
| 09 | -0.506 | 0.008 | -0.051 | 0.364 |
| P-value | Threshold |
|---|---|
| 0.001 | 3.22982 |
| 0.0005 | 6.164525 |
| 0.0001 | 7.86662 |