| Motif | SOX17.H12INVITRO.0.PS.A |
| Gene (human) | SOX17 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Sox17 |
| Gene synonyms (mouse) | Sox-17 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | SOX17.H12INVITRO.0.PS.A |
| Gene (human) | SOX17 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Sox17 |
| Gene synonyms (mouse) | Sox-17 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 8 |
| Consensus | nMATTGWn |
| GC content | 33.14% |
| Information content (bits; total / per base) | 8.171 / 1.021 |
| Data sources | ChIP-Seq + HT-SELEX |
| Aligned words | 7721 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 5 (31) | 0.766 | 0.812 | 0.612 | 0.67 | 0.732 | 0.758 | 1.943 | 2.073 | 99.854 | 182.796 |
| Mouse | 2 (10) | 0.707 | 0.745 | 0.628 | 0.658 | 0.657 | 0.706 | 1.878 | 1.987 | 83.475 | 122.066 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Non-Methyl HT-SELEX, 2 experiments | median | 0.633 | 0.603 | 0.576 | 0.563 | 0.538 | 0.538 |
| best | 0.657 | 0.625 | 0.589 | 0.576 | 0.544 | 0.546 | |
| TF superclass | Other all-alpha-helical DNA-binding domains {4} (TFClass) |
| TF class | High-mobility group (HMG) domain factors {4.1} (TFClass) |
| TF family | SOX-related {4.1.1} (TFClass) |
| TF subfamily | Group F {4.1.1.6} (TFClass) |
| TFClass ID | TFClass: 4.1.1.6.2 |
| HGNC | HGNC:18122 |
| MGI | MGI:107543 |
| EntrezGene (human) | GeneID:64321 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:20671 (SSTAR profile) |
| UniProt ID (human) | SOX17_HUMAN |
| UniProt ID (mouse) | SOX17_MOUSE |
| UniProt AC (human) | Q9H6I2 (TFClass) |
| UniProt AC (mouse) | Q61473 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 5 human, 2 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 0 |
| PCM | SOX17.H12INVITRO.0.PS.A.pcm |
| PWM | SOX17.H12INVITRO.0.PS.A.pwm |
| PFM | SOX17.H12INVITRO.0.PS.A.pfm |
| Alignment | SOX17.H12INVITRO.0.PS.A.words.tsv |
| Threshold to P-value map | SOX17.H12INVITRO.0.PS.A.thr |
| Motif in other formats | |
| JASPAR format | SOX17.H12INVITRO.0.PS.A_jaspar_format.txt |
| MEME format | SOX17.H12INVITRO.0.PS.A_meme_format.meme |
| Transfac format | SOX17.H12INVITRO.0.PS.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1407.75 | 2091.75 | 1638.75 | 2582.75 |
| 02 | 1930.25 | 4388.25 | 125.25 | 1277.25 |
| 03 | 7669.0 | 19.0 | 19.0 | 14.0 |
| 04 | 0.0 | 29.0 | 0.0 | 7692.0 |
| 05 | 0.0 | 8.0 | 0.0 | 7713.0 |
| 06 | 2.0 | 2346.0 | 5373.0 | 0.0 |
| 07 | 1835.5 | 531.5 | 514.5 | 4839.5 |
| 08 | 1366.75 | 1721.75 | 1662.75 | 2969.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.182 | 0.271 | 0.212 | 0.335 |
| 02 | 0.25 | 0.568 | 0.016 | 0.165 |
| 03 | 0.993 | 0.002 | 0.002 | 0.002 |
| 04 | 0.0 | 0.004 | 0.0 | 0.996 |
| 05 | 0.0 | 0.001 | 0.0 | 0.999 |
| 06 | 0.0 | 0.304 | 0.696 | 0.0 |
| 07 | 0.238 | 0.069 | 0.067 | 0.627 |
| 08 | 0.177 | 0.223 | 0.215 | 0.385 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.315 | 0.08 | -0.164 | 0.291 |
| 02 | 0.0 | 0.821 | -2.719 | -0.412 |
| 03 | 1.379 | -4.511 | -4.511 | -4.779 |
| 04 | -6.761 | -4.125 | -6.761 | 1.382 |
| 05 | -6.761 | -5.24 | -6.761 | 1.384 |
| 06 | -6.122 | 0.195 | 1.023 | -6.761 |
| 07 | -0.05 | -1.287 | -1.319 | 0.918 |
| 08 | -0.345 | -0.114 | -0.149 | 0.43 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.62436 |
| 0.0005 | 6.15395 |
| 0.0001 | 6.8717 |