SOX14.H12INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SOX14.H12INVITRO.0.SM.B
Gene (human)	SOX14 (GeneCards)
Gene synonyms (human)	SOX28
Gene (mouse)	Sox14
Gene synonyms (mouse)	Sox-14
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	15
Consensus	vhMAWWdvCATTGTb
GC content	32.28%
Information content (bits; total / per base)	14.216 / 0.948
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9660

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.997	0.996	0.976	0.969	0.901	0.896
Overall, 4 experiments	best	0.999	0.998	0.984	0.98	0.92	0.907
Methyl HT-SELEX, 2 experiments	median	0.994	0.992	0.954	0.947	0.848	0.85
Methyl HT-SELEX, 2 experiments	best	0.997	0.996	0.976	0.969	0.92	0.907
Non-Methyl HT-SELEX, 2 experiments	median	0.998	0.997	0.98	0.975	0.901	0.896
Non-Methyl HT-SELEX, 2 experiments	best	0.999	0.998	0.984	0.98	0.904	0.901

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.661	0.342	0.648	0.47

TF superclass	Other all-alpha-helical DNA-binding domains {4} (TFClass)
TF class	High-mobility group (HMG) domain factors {4.1} (TFClass)
TF family	SOX-related {4.1.1} (TFClass)
TF subfamily	Group B {4.1.1.2} (TFClass)
TFClass ID	TFClass: 4.1.1.2.4
HGNC	HGNC:11193
MGI	MGI:98362
EntrezGene (human)	GeneID:8403 (SSTAR profile)
EntrezGene (mouse)	GeneID:20669 (SSTAR profile)
UniProt ID (human)	SOX14_HUMAN
UniProt ID (mouse)	SOX14_MOUSE
UniProt AC (human)	O95416 (TFClass)
UniProt AC (mouse)	Q04892 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	2

PCM	SOX14.H12INVITRO.0.SM.B.pcm
PWM	SOX14.H12INVITRO.0.SM.B.pwm
PFM	SOX14.H12INVITRO.0.SM.B.pfm
Alignment	SOX14.H12INVITRO.0.SM.B.words.tsv
Threshold to P-value map	SOX14.H12INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	SOX14.H12INVITRO.0.SM.B_jaspar_format.txt
MEME format	SOX14.H12INVITRO.0.SM.B_meme_format.meme
Transfac format	SOX14.H12INVITRO.0.SM.B_transfac_format.txt
Homer format	SOX14.H12INVITRO.0.SM.B_homer_format_0.001.txt SOX14.H12INVITRO.0.SM.B_homer_format_0.0005.txt SOX14.H12INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	4191.5	1944.5	1989.5	1534.5
02	5484.5	1889.5	508.5	1777.5
03	2143.0	5897.0	1080.0	540.0
04	8215.0	346.0	342.0	757.0
05	6761.0	482.0	447.0	1970.0
06	1157.0	442.0	679.0	7382.0
07	4749.0	593.0	1999.0	2319.0
08	3083.0	3371.0	2253.0	953.0
09	823.0	8454.0	2.0	381.0
10	9659.0	1.0	0.0	0.0
11	26.0	4.0	0.0	9630.0
12	0.0	0.0	0.0	9660.0
13	85.0	790.0	8783.0	2.0
14	1445.0	386.0	180.0	7649.0
15	1464.25	2307.25	1605.25	4283.25

PFM

	A	C	G	T
01	0.434	0.201	0.206	0.159
02	0.568	0.196	0.053	0.184
03	0.222	0.61	0.112	0.056
04	0.85	0.036	0.035	0.078
05	0.7	0.05	0.046	0.204
06	0.12	0.046	0.07	0.764
07	0.492	0.061	0.207	0.24
08	0.319	0.349	0.233	0.099
09	0.085	0.875	0.0	0.039
10	1.0	0.0	0.0	0.0
11	0.003	0.0	0.0	0.997
12	0.0	0.0	0.0	1.0
13	0.009	0.082	0.909	0.0
14	0.15	0.04	0.019	0.792
15	0.152	0.239	0.166	0.443

PWM

	A	C	G	T
01	0.551	-0.216	-0.194	-0.453
02	0.82	-0.245	-1.554	-0.306
03	-0.119	0.892	-0.804	-1.495
04	1.224	-1.937	-1.949	-1.158
05	1.029	-1.608	-1.683	-0.203
06	-0.735	-1.694	-1.266	1.117
07	0.676	-1.401	-0.189	-0.041
08	0.244	0.333	-0.069	-0.928
09	-1.075	1.252	-6.333	-1.842
10	1.385	-6.598	-6.96	-6.96
11	-4.448	-5.951	-6.96	1.382
12	-6.96	-6.96	-6.96	1.386
13	-3.321	-1.115	1.29	-6.333
14	-0.513	-1.829	-2.585	1.152
15	-0.5	-0.046	-0.408	0.573

Standard thresholds

P-value	Threshold
0.001	2.89476
0.0005	4.25486
0.0001	6.84026