SOX14.H12CORE.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SOX14.H12CORE.0.SM.B
Gene (human)	SOX14 (GeneCards)
Gene synonyms (human)	SOX28
Gene (mouse)	Sox14
Gene synonyms (mouse)	Sox-14
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	19
Consensus	dMMAATRnCATTGTYMnnn
GC content	36.9%
Information content (bits; total / per base)	18.918 / 0.996
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	245

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.995	0.994	0.969	0.961	0.876	0.871
Overall, 4 experiments	best	0.998	0.997	0.973	0.968	0.904	0.893
Methyl HT-SELEX, 2 experiments	median	0.991	0.988	0.939	0.931	0.83	0.831
Methyl HT-SELEX, 2 experiments	best	0.995	0.993	0.972	0.964	0.904	0.893
Non-Methyl HT-SELEX, 2 experiments	median	0.997	0.996	0.969	0.963	0.876	0.871
Non-Methyl HT-SELEX, 2 experiments	best	0.998	0.997	0.973	0.968	0.877	0.874

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.685	0.373	0.687	0.475

TF superclass	Other all-alpha-helical DNA-binding domains {4} (TFClass)
TF class	High-mobility group (HMG) domain factors {4.1} (TFClass)
TF family	SOX-related {4.1.1} (TFClass)
TF subfamily	Group B {4.1.1.2} (TFClass)
TFClass ID	TFClass: 4.1.1.2.4
HGNC	HGNC:11193
MGI	MGI:98362
EntrezGene (human)	GeneID:8403 (SSTAR profile)
EntrezGene (mouse)	GeneID:20669 (SSTAR profile)
UniProt ID (human)	SOX14_HUMAN
UniProt ID (mouse)	SOX14_MOUSE
UniProt AC (human)	O95416 (TFClass)
UniProt AC (mouse)	Q04892 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	2

PCM	SOX14.H12CORE.0.SM.B.pcm
PWM	SOX14.H12CORE.0.SM.B.pwm
PFM	SOX14.H12CORE.0.SM.B.pfm
Alignment	SOX14.H12CORE.0.SM.B.words.tsv
Threshold to P-value map	SOX14.H12CORE.0.SM.B.thr
Motif in other formats
JASPAR format	SOX14.H12CORE.0.SM.B_jaspar_format.txt
MEME format	SOX14.H12CORE.0.SM.B_meme_format.meme
Transfac format	SOX14.H12CORE.0.SM.B_transfac_format.txt
Homer format	SOX14.H12CORE.0.SM.B_homer_format_0.001.txt SOX14.H12CORE.0.SM.B_homer_format_0.0005.txt SOX14.H12CORE.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	110.75	38.75	43.75	51.75
02	173.0	54.0	3.0	15.0
03	50.0	184.0	7.0	4.0
04	237.0	2.0	1.0	5.0
05	189.0	1.0	2.0	53.0
06	10.0	1.0	15.0	219.0
07	69.0	11.0	139.0	26.0
08	41.0	86.0	68.0	50.0
09	12.0	181.0	0.0	52.0
10	245.0	0.0	0.0	0.0
11	0.0	0.0	0.0	245.0
12	0.0	0.0	0.0	245.0
13	0.0	0.0	245.0	0.0
14	4.0	0.0	0.0	241.0
15	11.0	49.0	21.0	164.0
16	103.0	111.0	15.0	16.0
17	49.0	77.0	80.0	39.0
18	26.75	80.75	68.75	68.75
19	56.25	54.25	78.25	56.25

PFM

	A	C	G	T
01	0.452	0.158	0.179	0.211
02	0.706	0.22	0.012	0.061
03	0.204	0.751	0.029	0.016
04	0.967	0.008	0.004	0.02
05	0.771	0.004	0.008	0.216
06	0.041	0.004	0.061	0.894
07	0.282	0.045	0.567	0.106
08	0.167	0.351	0.278	0.204
09	0.049	0.739	0.0	0.212
10	1.0	0.0	0.0	0.0
11	0.0	0.0	0.0	1.0
12	0.0	0.0	0.0	1.0
13	0.0	0.0	1.0	0.0
14	0.016	0.0	0.0	0.984
15	0.045	0.2	0.086	0.669
16	0.42	0.453	0.061	0.065
17	0.2	0.314	0.327	0.159
18	0.109	0.33	0.281	0.281
19	0.23	0.221	0.319	0.23

PWM

	A	C	G	T
01	0.582	-0.445	-0.328	-0.165
02	1.024	-0.123	-2.661	-1.341
03	-0.198	1.085	-2.012	-2.455
04	1.337	-2.921	-3.272	-2.285
05	1.112	-3.272	-2.921	-0.141
06	-1.706	-3.272	-1.341	1.258
07	0.117	-1.621	0.807	-0.828
08	-0.391	0.333	0.102	-0.198
09	-1.544	1.069	-3.818	-0.16
10	1.37	-3.818	-3.818	-3.818
11	-3.818	-3.818	-3.818	1.37
12	-3.818	-3.818	-3.818	1.37
13	-3.818	-3.818	1.37	-3.818
14	-2.455	-3.818	-3.818	1.353
15	-1.621	-0.218	-1.029	0.971
16	0.511	0.585	-1.341	-1.282
17	-0.218	0.224	0.262	-0.439
18	-0.8	0.271	0.113	0.113
19	-0.083	-0.119	0.24	-0.083

Standard thresholds

P-value	Threshold
0.001	1.06236
0.0005	2.45991
0.0001	5.40331