MotifSOX14.H12CORE.0.SM.B
Gene (human)SOX14
(GeneCards)
Gene synonyms (human)SOX28
Gene (mouse)Sox14
Gene synonyms (mouse)Sox-14
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length19
ConsensusdMMAATRnCATTGTYMnnn
GC content36.9%
Information content (bits; total / per base)18.918 / 0.996
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words245

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.995 0.994 0.969 0.961 0.876 0.871
best 0.998 0.997 0.973 0.968 0.904 0.893
Methyl HT-SELEX, 2 experiments median 0.991 0.988 0.939 0.931 0.83 0.831
best 0.995 0.993 0.972 0.964 0.904 0.893
Non-Methyl HT-SELEX, 2 experiments median 0.997 0.996 0.969 0.963 0.876 0.871
best 0.998 0.997 0.973 0.968 0.877 0.874

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.685 0.373 0.687 0.475
TF superclassOther all-alpha-helical DNA-binding domains {4} (TFClass)
TF classHigh-mobility group (HMG) domain factors {4.1} (TFClass)
TF familySOX-related {4.1.1} (TFClass)
TF subfamilyGroup B {4.1.1.2} (TFClass)
TFClass IDTFClass: 4.1.1.2.4
HGNCHGNC:11193
MGIMGI:98362
EntrezGene (human)GeneID:8403
(SSTAR profile)
EntrezGene (mouse)GeneID:20669
(SSTAR profile)
UniProt ID (human)SOX14_HUMAN
UniProt ID (mouse)SOX14_MOUSE
UniProt AC (human)O95416
(TFClass)
UniProt AC (mouse)Q04892
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
01110.7538.7543.7551.75
02173.054.03.015.0
0350.0184.07.04.0
04237.02.01.05.0
05189.01.02.053.0
0610.01.015.0219.0
0769.011.0139.026.0
0841.086.068.050.0
0912.0181.00.052.0
10245.00.00.00.0
110.00.00.0245.0
120.00.00.0245.0
130.00.0245.00.0
144.00.00.0241.0
1511.049.021.0164.0
16103.0111.015.016.0
1749.077.080.039.0
1826.7580.7568.7568.75
1956.2554.2578.2556.25
PFM
ACGT
010.4520.1580.1790.211
020.7060.220.0120.061
030.2040.7510.0290.016
040.9670.0080.0040.02
050.7710.0040.0080.216
060.0410.0040.0610.894
070.2820.0450.5670.106
080.1670.3510.2780.204
090.0490.7390.00.212
101.00.00.00.0
110.00.00.01.0
120.00.00.01.0
130.00.01.00.0
140.0160.00.00.984
150.0450.20.0860.669
160.420.4530.0610.065
170.20.3140.3270.159
180.1090.330.2810.281
190.230.2210.3190.23
PWM
ACGT
010.582-0.445-0.328-0.165
021.024-0.123-2.661-1.341
03-0.1981.085-2.012-2.455
041.337-2.921-3.272-2.285
051.112-3.272-2.921-0.141
06-1.706-3.272-1.3411.258
070.117-1.6210.807-0.828
08-0.3910.3330.102-0.198
09-1.5441.069-3.818-0.16
101.37-3.818-3.818-3.818
11-3.818-3.818-3.8181.37
12-3.818-3.818-3.8181.37
13-3.818-3.8181.37-3.818
14-2.455-3.818-3.8181.353
15-1.621-0.218-1.0290.971
160.5110.585-1.341-1.282
17-0.2180.2240.262-0.439
18-0.80.2710.1130.113
19-0.083-0.1190.24-0.083
Standard thresholds
P-value Threshold
0.001 1.06236
0.0005 2.45991
0.0001 5.40331