MotifSOX1.H12CORE.0.S.B
Gene (human)SOX1
(GeneCards)
Gene synonyms (human)
Gene (mouse)Sox1
Gene synonyms (mouse)Sox-1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length17
ConsensusdWSAATWnCATTCWYhn
GC content30.94%
Information content (bits; total / per base)17.635 / 1.037
Data sourcesHT-SELEX
Aligned words455

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.605 0.588 0.564 0.554 0.54 0.536
best 0.636 0.621 0.579 0.572 0.547 0.546
TF superclassOther all-alpha-helical DNA-binding domains {4} (TFClass)
TF classHigh-mobility group (HMG) domain factors {4.1} (TFClass)
TF familySOX-related {4.1.1} (TFClass)
TF subfamilyGroup B {4.1.1.2} (TFClass)
TFClass IDTFClass: 4.1.1.2.1
HGNCHGNC:11189
MGIMGI:98357
EntrezGene (human)GeneID:6656
(SSTAR profile)
EntrezGene (mouse)GeneID:20664
(SSTAR profile)
UniProt ID (human)SOX1_HUMAN
UniProt ID (mouse)SOX1_MOUSE
UniProt AC (human)O00570
(TFClass)
UniProt AC (mouse)P53783
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
01236.060.077.082.0
02117.2527.2512.25298.25
0310.0116.0320.09.0
04418.026.08.03.0
05408.027.05.015.0
061.05.04.0445.0
07276.09.068.0102.0
08152.0114.078.0111.0
090.0452.00.03.0
10454.01.00.00.0
110.00.00.0455.0
120.00.00.0455.0
130.0363.090.02.0
14295.038.025.097.0
1536.0116.031.0272.0
16110.591.556.5196.5
17103.7594.7577.75178.75
PFM
ACGT
010.5190.1320.1690.18
020.2580.060.0270.655
030.0220.2550.7030.02
040.9190.0570.0180.007
050.8970.0590.0110.033
060.0020.0110.0090.978
070.6070.020.1490.224
080.3340.2510.1710.244
090.00.9930.00.007
100.9980.0020.00.0
110.00.00.01.0
120.00.00.01.0
130.00.7980.1980.004
140.6480.0840.0550.213
150.0790.2550.0680.598
160.2430.2010.1240.432
170.2280.2080.1710.393
PWM
ACGT
010.723-0.628-0.384-0.322
020.03-1.388-2.1240.956
03-2.3020.0191.026-2.393
041.292-1.432-2.493-3.237
051.268-1.396-2.871-1.942
06-3.819-2.871-3.0371.354
070.879-2.393-0.506-0.108
080.2870.002-0.371-0.024
09-4.3221.37-4.322-3.237
101.374-3.819-4.322-4.322
11-4.322-4.322-4.3221.376
12-4.322-4.322-4.3221.376
13-4.3221.151-0.231-3.486
140.945-1.07-1.469-0.157
15-1.1220.019-1.2650.864
16-0.029-0.214-0.6860.541
17-0.091-0.18-0.3740.447
Standard thresholds
P-value Threshold
0.001 1.33581
0.0005 2.73796
0.0001 5.67821