MotifSNAI2.H12INVIVO.0.PSM.A
Gene (human)SNAI2
(GeneCards)
Gene synonyms (human)SLUG, SLUGH
Gene (mouse)Snai2
Gene synonyms (mouse)Slug, Slugh
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length11
ConsensusdRCAGGTGYnb
GC content61.4%
Information content (bits; total / per base)13.888 / 1.263
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words996

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 14 (76) 0.916 0.967 0.816 0.901 0.923 0.976 3.727 4.333 218.367 709.796

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 5 experiments median 0.997 0.994 0.994 0.99 0.99 0.985
best 0.999 0.997 0.997 0.995 0.995 0.992
Methyl HT-SELEX, 2 experiments median 0.996 0.993 0.989 0.984 0.908 0.916
best 0.998 0.996 0.997 0.994 0.995 0.992
Non-Methyl HT-SELEX, 3 experiments median 0.997 0.994 0.994 0.99 0.99 0.985
best 0.999 0.997 0.997 0.995 0.995 0.992

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 3.36 13.988 0.161 0.278

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.988 0.862 0.956 0.557
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMore than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamilySnail-like {2.3.3.2} (TFClass)
TFClass IDTFClass: 2.3.3.2.2
HGNCHGNC:11094
MGIMGI:1096393
EntrezGene (human)GeneID:6591
(SSTAR profile)
EntrezGene (mouse)GeneID:20583
(SSTAR profile)
UniProt ID (human)SNAI2_HUMAN
UniProt ID (mouse)SNAI2_MOUSE
UniProt AC (human)O43623
(TFClass)
UniProt AC (mouse)P97469
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 14 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 2
PCM
ACGT
01418.049.0426.0103.0
02440.00.0550.06.0
030.0995.00.01.0
04995.00.01.00.0
056.00.0990.00.0
061.00.0995.00.0
071.01.00.0994.0
081.00.0992.03.0
0927.0594.0165.0210.0
10381.0234.0192.0189.0
11111.0234.0309.0342.0
PFM
ACGT
010.420.0490.4280.103
020.4420.00.5520.006
030.00.9990.00.001
040.9990.00.0010.0
050.0060.00.9940.0
060.0010.00.9990.0
070.0010.0010.00.998
080.0010.00.9960.003
090.0270.5960.1660.211
100.3830.2350.1930.19
110.1110.2350.310.343
PWM
ACGT
010.515-1.5980.534-0.873
020.566-4.9790.789-3.48
03-4.9791.38-4.979-4.522
041.38-4.979-4.522-4.979
05-3.48-4.9791.375-4.979
06-4.522-4.9791.38-4.979
07-4.522-4.522-4.9791.379
08-4.522-4.9791.377-3.971
09-2.1670.865-0.408-0.169
100.423-0.062-0.258-0.274
11-0.799-0.0620.2150.315
Standard thresholds
P-value Threshold
0.001 2.617935
0.0005 3.575805
0.0001 6.710075