| Motif | SMAD5.H12INVITRO.0.M.C |
| Gene (human) | SMAD5 (GeneCards) |
| Gene synonyms (human) | MADH5 |
| Gene (mouse) | Smad5 |
| Gene synonyms (mouse) | Madh5, Msmad5 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | C |
| Motif | SMAD5.H12INVITRO.0.M.C |
| Gene (human) | SMAD5 (GeneCards) |
| Gene synonyms (human) | MADH5 |
| Gene (mouse) | Smad5 |
| Gene synonyms (mouse) | Madh5, Msmad5 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | C |
| Motif length | 10 |
| Consensus | nCGTCTvvhn |
| GC content | 58.57% |
| Information content (bits; total / per base) | 9.632 / 0.963 |
| Data sources | Methyl-HT-SELEX |
| Aligned words | 5632 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Methyl HT-SELEX, 1 experiments | median | 0.797 | 0.76 | 0.653 | 0.652 | 0.55 | 0.581 |
| best | 0.797 | 0.76 | 0.653 | 0.652 | 0.55 | 0.581 | |
| TF superclass | beta-Hairpin exposed by an alpha/beta-scaffold {7} (TFClass) |
| TF class | SMAD/NF-1 DNA-binding domain factors {7.1} (TFClass) |
| TF family | SMAD {7.1.1} (TFClass) |
| TF subfamily | R-MAD {7.1.1.1} (TFClass) |
| TFClass ID | TFClass: 7.1.1.1.4 |
| HGNC | HGNC:6771 |
| MGI | MGI:1328787 |
| EntrezGene (human) | GeneID:4090 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:17129 (SSTAR profile) |
| UniProt ID (human) | SMAD5_HUMAN |
| UniProt ID (mouse) | SMAD5_MOUSE |
| UniProt AC (human) | Q99717 (TFClass) |
| UniProt AC (mouse) | P97454 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 0 |
| Methyl-HT-SELEX | 1 |
| PCM | SMAD5.H12INVITRO.0.M.C.pcm |
| PWM | SMAD5.H12INVITRO.0.M.C.pwm |
| PFM | SMAD5.H12INVITRO.0.M.C.pfm |
| Alignment | SMAD5.H12INVITRO.0.M.C.words.tsv |
| Threshold to P-value map | SMAD5.H12INVITRO.0.M.C.thr |
| Motif in other formats | |
| JASPAR format | SMAD5.H12INVITRO.0.M.C_jaspar_format.txt |
| MEME format | SMAD5.H12INVITRO.0.M.C_meme_format.meme |
| Transfac format | SMAD5.H12INVITRO.0.M.C_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1539.5 | 1389.5 | 1577.5 | 1125.5 |
| 02 | 94.0 | 4040.0 | 42.0 | 1456.0 |
| 03 | 34.0 | 67.0 | 5531.0 | 0.0 |
| 04 | 0.0 | 166.0 | 0.0 | 5466.0 |
| 05 | 0.0 | 5632.0 | 0.0 | 0.0 |
| 06 | 0.0 | 0.0 | 0.0 | 5632.0 |
| 07 | 2110.0 | 788.0 | 2440.0 | 294.0 |
| 08 | 814.0 | 2501.0 | 1929.0 | 388.0 |
| 09 | 1478.75 | 2932.75 | 545.75 | 674.75 |
| 10 | 1202.5 | 1891.5 | 1514.5 | 1023.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.273 | 0.247 | 0.28 | 0.2 |
| 02 | 0.017 | 0.717 | 0.007 | 0.259 |
| 03 | 0.006 | 0.012 | 0.982 | 0.0 |
| 04 | 0.0 | 0.029 | 0.0 | 0.971 |
| 05 | 0.0 | 1.0 | 0.0 | 0.0 |
| 06 | 0.0 | 0.0 | 0.0 | 1.0 |
| 07 | 0.375 | 0.14 | 0.433 | 0.052 |
| 08 | 0.145 | 0.444 | 0.343 | 0.069 |
| 09 | 0.263 | 0.521 | 0.097 | 0.12 |
| 10 | 0.214 | 0.336 | 0.269 | 0.182 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.089 | -0.013 | 0.114 | -0.224 |
| 02 | -2.685 | 1.053 | -3.464 | 0.033 |
| 03 | -3.664 | -3.015 | 1.367 | -6.482 |
| 04 | -6.482 | -2.127 | -6.482 | 1.355 |
| 05 | -6.482 | 1.385 | -6.482 | -6.482 |
| 06 | -6.482 | -6.482 | -6.482 | 1.385 |
| 07 | 0.404 | -0.579 | 0.549 | -1.561 |
| 08 | -0.547 | 0.574 | 0.314 | -1.285 |
| 09 | 0.049 | 0.733 | -0.945 | -0.734 |
| 10 | -0.158 | 0.295 | 0.073 | -0.318 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.251565 |
| 0.0005 | 6.24098 |
| 0.0001 | 7.529625 |