MotifSMAD4.H12INVIVO.1.P.B
Gene (human)SMAD4
(GeneCards)
Gene synonyms (human)DPC4, MADH4
Gene (mouse)Smad4
Gene synonyms (mouse)Dpc4, Madh4
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length13
ConsensusvWGKCTSdCWSYh
GC content55.97%
Information content (bits; total / per base)11.066 / 0.851
Data sourcesChIP-Seq
Aligned words1021

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 5 (29) 0.624 0.874 0.446 0.8 0.606 0.878 1.562 3.854 13.886 222.745
Mouse 1 (5) 0.688 0.701 0.58 0.6 0.67 0.705 2.464 2.595 44.215 71.155
TF superclassbeta-Hairpin exposed by an alpha/beta-scaffold {7} (TFClass)
TF classSMAD/NF-1 DNA-binding domain factors {7.1} (TFClass)
TF familySMAD {7.1.1} (TFClass)
TF subfamilyCo-SMAD {7.1.1.2} (TFClass)
TFClass IDTFClass: 7.1.1.2.1
HGNCHGNC:6770
MGIMGI:894293
EntrezGene (human)GeneID:4089
(SSTAR profile)
EntrezGene (mouse)GeneID:17128
(SSTAR profile)
UniProt ID (human)SMAD4_HUMAN
UniProt ID (mouse)SMAD4_MOUSE
UniProt AC (human)Q13485
(TFClass)
UniProt AC (mouse)P97471
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 5 human, 1 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
01207.0438.0226.0150.0
02256.0125.048.0592.0
0322.020.0968.011.0
0443.052.0146.0780.0
054.0997.011.09.0
066.06.02.01007.0
07141.0210.0632.038.0
08221.0134.0381.0285.0
0934.0907.052.028.0
10743.036.095.0147.0
1169.0762.0150.040.0
12134.0607.071.0209.0
13136.0251.0102.0532.0
PFM
ACGT
010.2030.4290.2210.147
020.2510.1220.0470.58
030.0220.020.9480.011
040.0420.0510.1430.764
050.0040.9760.0110.009
060.0060.0060.0020.986
070.1380.2060.6190.037
080.2160.1310.3730.279
090.0330.8880.0510.027
100.7280.0350.0930.144
110.0680.7460.1470.039
120.1310.5950.070.205
130.1330.2460.10.521
PWM
ACGT
01-0.2080.537-0.121-0.527
020.003-0.707-1.6420.837
03-2.382-2.471.328-3.005
04-1.748-1.565-0.5541.113
05-3.8031.357-3.005-3.176
06-3.504-3.504-4.2321.367
07-0.588-0.1940.903-1.867
08-0.143-0.6380.3980.11
09-1.9731.263-1.565-2.157
101.064-1.918-0.977-0.547
11-1.291.089-0.527-1.818
12-0.6380.862-1.262-0.198
13-0.624-0.017-0.9070.731
Standard thresholds
P-value Threshold
0.001 4.48091
0.0005 5.39206
0.0001 7.24893