| Motif | SMAD4.H12CORE.0.P.B |
| Gene (human) | SMAD4 (GeneCards) |
| Gene synonyms (human) | DPC4, MADH4 |
| Gene (mouse) | Smad4 |
| Gene synonyms (mouse) | Dpc4, Madh4 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | SMAD4.H12CORE.0.P.B |
| Gene (human) | SMAD4 (GeneCards) |
| Gene synonyms (human) | DPC4, MADH4 |
| Gene (mouse) | Smad4 |
| Gene synonyms (mouse) | Dpc4, Madh4 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 8 |
| Consensus | YGKCTGbv |
| GC content | 62.08% |
| Information content (bits; total / per base) | 8.63 / 1.079 |
| Data sources | ChIP-Seq |
| Aligned words | 1002 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 5 (29) | 0.687 | 0.749 | 0.549 | 0.602 | 0.634 | 0.727 | 1.593 | 1.88 | 36.538 | 72.678 |
| Mouse | 1 (5) | 0.649 | 0.667 | 0.496 | 0.513 | 0.62 | 0.64 | 1.527 | 1.582 | 32.31 | 47.114 |
| TF superclass | beta-Hairpin exposed by an alpha/beta-scaffold {7} (TFClass) |
| TF class | SMAD/NF-1 DNA-binding domain factors {7.1} (TFClass) |
| TF family | SMAD {7.1.1} (TFClass) |
| TF subfamily | Co-SMAD {7.1.1.2} (TFClass) |
| TFClass ID | TFClass: 7.1.1.2.1 |
| HGNC | HGNC:6770 |
| MGI | MGI:894293 |
| EntrezGene (human) | GeneID:4089 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:17128 (SSTAR profile) |
| UniProt ID (human) | SMAD4_HUMAN |
| UniProt ID (mouse) | SMAD4_MOUSE |
| UniProt AC (human) | Q13485 (TFClass) |
| UniProt AC (mouse) | P97471 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 5 human, 1 mouse |
| HT-SELEX | 0 |
| Methyl-HT-SELEX | 0 |
| PCM | SMAD4.H12CORE.0.P.B.pcm |
| PWM | SMAD4.H12CORE.0.P.B.pwm |
| PFM | SMAD4.H12CORE.0.P.B.pfm |
| Alignment | SMAD4.H12CORE.0.P.B.words.tsv |
| Threshold to P-value map | SMAD4.H12CORE.0.P.B.thr |
| Motif in other formats | |
| JASPAR format | SMAD4.H12CORE.0.P.B_jaspar_format.txt |
| MEME format | SMAD4.H12CORE.0.P.B_meme_format.meme |
| Transfac format | SMAD4.H12CORE.0.P.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 156.0 | 248.0 | 29.0 | 569.0 |
| 02 | 6.0 | 29.0 | 948.0 | 19.0 |
| 03 | 20.0 | 50.0 | 234.0 | 698.0 |
| 04 | 2.0 | 969.0 | 20.0 | 11.0 |
| 05 | 4.0 | 5.0 | 3.0 | 990.0 |
| 06 | 23.0 | 24.0 | 945.0 | 10.0 |
| 07 | 56.0 | 290.0 | 532.0 | 124.0 |
| 08 | 223.0 | 303.0 | 347.0 | 129.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.156 | 0.248 | 0.029 | 0.568 |
| 02 | 0.006 | 0.029 | 0.946 | 0.019 |
| 03 | 0.02 | 0.05 | 0.234 | 0.697 |
| 04 | 0.002 | 0.967 | 0.02 | 0.011 |
| 05 | 0.004 | 0.005 | 0.003 | 0.988 |
| 06 | 0.023 | 0.024 | 0.943 | 0.01 |
| 07 | 0.056 | 0.289 | 0.531 | 0.124 |
| 08 | 0.223 | 0.302 | 0.346 | 0.129 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.469 | -0.01 | -2.105 | 0.817 |
| 02 | -3.486 | -2.105 | 1.326 | -2.499 |
| 03 | -2.452 | -1.584 | -0.068 | 1.02 |
| 04 | -4.215 | 1.348 | -2.452 | -2.987 |
| 05 | -3.785 | -3.624 | -3.977 | 1.369 |
| 06 | -2.322 | -2.283 | 1.323 | -3.068 |
| 07 | -1.475 | 0.145 | 0.75 | -0.696 |
| 08 | -0.115 | 0.189 | 0.324 | -0.657 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.101475 |
| 0.0005 | 6.037335 |
| 0.0001 | 7.312635 |