| Motif | SMAD2.H12INVITRO.1.P.D |
| Gene (human) | SMAD2 (GeneCards) |
| Gene synonyms (human) | MADH2, MADR2 |
| Gene (mouse) | Smad2 |
| Gene synonyms (mouse) | Madh2, Madr2 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | D |
| Motif | SMAD2.H12INVITRO.1.P.D |
| Gene (human) | SMAD2 (GeneCards) |
| Gene synonyms (human) | MADH2, MADR2 |
| Gene (mouse) | Smad2 |
| Gene synonyms (mouse) | Madh2, Madr2 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | D |
| Motif length | 10 |
| Consensus | bYTGTCTGbv |
| GC content | 57.46% |
| Information content (bits; total / per base) | 10.427 / 1.043 |
| Data sources | ChIP-Seq |
| Aligned words | 1000 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 10 (67) | 0.692 | 0.735 | 0.531 | 0.585 | 0.668 | 0.708 | 1.721 | 1.929 | 22.854 | 49.854 |
| Mouse | 6 (41) | 0.668 | 0.738 | 0.487 | 0.566 | 0.699 | 0.771 | 1.905 | 2.226 | 31.018 | 80.678 |
| TF superclass | beta-Hairpin exposed by an alpha/beta-scaffold {7} (TFClass) |
| TF class | SMAD/NF-1 DNA-binding domain factors {7.1} (TFClass) |
| TF family | SMAD {7.1.1} (TFClass) |
| TF subfamily | R-MAD {7.1.1.1} (TFClass) |
| TFClass ID | TFClass: 7.1.1.1.2 |
| HGNC | HGNC:6768 |
| MGI | MGI:108051 |
| EntrezGene (human) | GeneID:4087 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:17126 (SSTAR profile) |
| UniProt ID (human) | SMAD2_HUMAN |
| UniProt ID (mouse) | SMAD2_MOUSE |
| UniProt AC (human) | Q15796 (TFClass) |
| UniProt AC (mouse) | Q62432 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 10 human, 6 mouse |
| HT-SELEX | 0 |
| Methyl-HT-SELEX | 0 |
| PCM | SMAD2.H12INVITRO.1.P.D.pcm |
| PWM | SMAD2.H12INVITRO.1.P.D.pwm |
| PFM | SMAD2.H12INVITRO.1.P.D.pfm |
| Alignment | SMAD2.H12INVITRO.1.P.D.words.tsv |
| Threshold to P-value map | SMAD2.H12INVITRO.1.P.D.thr |
| Motif in other formats | |
| JASPAR format | SMAD2.H12INVITRO.1.P.D_jaspar_format.txt |
| MEME format | SMAD2.H12INVITRO.1.P.D_meme_format.meme |
| Transfac format | SMAD2.H12INVITRO.1.P.D_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 98.0 | 244.0 | 315.0 | 343.0 |
| 02 | 43.0 | 686.0 | 115.0 | 156.0 |
| 03 | 110.0 | 15.0 | 1.0 | 874.0 |
| 04 | 1.0 | 10.0 | 981.0 | 8.0 |
| 05 | 12.0 | 52.0 | 77.0 | 859.0 |
| 06 | 1.0 | 904.0 | 14.0 | 81.0 |
| 07 | 5.0 | 0.0 | 2.0 | 993.0 |
| 08 | 55.0 | 39.0 | 897.0 | 9.0 |
| 09 | 74.0 | 266.0 | 441.0 | 219.0 |
| 10 | 169.0 | 486.0 | 201.0 | 144.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.098 | 0.244 | 0.315 | 0.343 |
| 02 | 0.043 | 0.686 | 0.115 | 0.156 |
| 03 | 0.11 | 0.015 | 0.001 | 0.874 |
| 04 | 0.001 | 0.01 | 0.981 | 0.008 |
| 05 | 0.012 | 0.052 | 0.077 | 0.859 |
| 06 | 0.001 | 0.904 | 0.014 | 0.081 |
| 07 | 0.005 | 0.0 | 0.002 | 0.993 |
| 08 | 0.055 | 0.039 | 0.897 | 0.009 |
| 09 | 0.074 | 0.266 | 0.441 | 0.219 |
| 10 | 0.169 | 0.486 | 0.201 | 0.144 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.926 | -0.024 | 0.23 | 0.314 |
| 02 | -1.728 | 1.005 | -0.769 | -0.467 |
| 03 | -0.812 | -2.711 | -4.525 | 1.247 |
| 04 | -4.525 | -3.066 | 1.362 | -3.253 |
| 05 | -2.909 | -1.544 | -1.162 | 1.229 |
| 06 | -4.525 | 1.28 | -2.773 | -1.113 |
| 07 | -3.622 | -4.982 | -4.213 | 1.374 |
| 08 | -1.49 | -1.821 | 1.273 | -3.156 |
| 09 | -1.201 | 0.062 | 0.565 | -0.131 |
| 10 | -0.388 | 0.661 | -0.216 | -0.547 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.64395 |
| 0.0005 | 5.599795 |
| 0.0001 | 7.407435 |