MotifSMAD2.H12INVITRO.0.P.D
Gene (human)SMAD2
(GeneCards)
Gene synonyms (human)MADH2, MADR2
Gene (mouse)Smad2
Gene synonyms (mouse)Madh2, Madr2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length12
ConsensusWGTCTSdMWSYh
GC content53.81%
Information content (bits; total / per base)10.148 / 0.846
Data sourcesChIP-Seq
Aligned words367

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 10 (67) 0.788 0.841 0.705 0.783 0.782 0.839 3.047 3.566 68.77 118.409
Mouse 6 (41) 0.655 0.736 0.491 0.618 0.654 0.731 1.78 2.429 14.398 74.638
TF superclassbeta-Hairpin exposed by an alpha/beta-scaffold {7} (TFClass)
TF classSMAD/NF-1 DNA-binding domain factors {7.1} (TFClass)
TF familySMAD {7.1.1} (TFClass)
TF subfamilyR-MAD {7.1.1.1} (TFClass)
TFClass IDTFClass: 7.1.1.1.2
HGNCHGNC:6768
MGIMGI:108051
EntrezGene (human)GeneID:4087
(SSTAR profile)
EntrezGene (mouse)GeneID:17126
(SSTAR profile)
UniProt ID (human)SMAD2_HUMAN
UniProt ID (mouse)SMAD2_MOUSE
UniProt AC (human)Q15796
(TFClass)
UniProt AC (mouse)Q62432
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 10 human, 6 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
01131.037.016.0183.0
0216.014.0329.08.0
0325.020.023.0299.0
041.0345.010.011.0
051.02.01.0363.0
0650.069.0238.010.0
0791.047.0144.085.0
0829.0295.021.022.0
09244.033.024.066.0
1017.0291.037.022.0
1149.0212.023.083.0
1260.094.045.0168.0
PFM
ACGT
010.3570.1010.0440.499
020.0440.0380.8960.022
030.0680.0540.0630.815
040.0030.940.0270.03
050.0030.0050.0030.989
060.1360.1880.6490.027
070.2480.1280.3920.232
080.0790.8040.0570.06
090.6650.090.0650.18
100.0460.7930.1010.06
110.1340.5780.0630.226
120.1630.2560.1230.458
PWM
ACGT
010.351-0.885-1.6740.682
02-1.674-1.7961.266-2.286
03-1.259-1.468-1.3371.17
04-3.6281.313-2.095-2.011
05-3.628-3.289-3.6281.363
06-0.594-0.280.943-2.095
07-0.008-0.6540.445-0.075
08-1.1181.157-1.423-1.379
090.968-0.995-1.297-0.323
10-1.6191.143-0.885-1.379
11-0.6140.828-1.337-0.099
12-0.4160.024-0.6960.598
Standard thresholds
P-value Threshold
0.001 4.72616
0.0005 5.53617
0.0001 7.20937