SKOR2.H12RSNP.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SKOR2.H12RSNP.0.SM.B
Gene (human)	SKOR2 (GeneCards)
Gene synonyms (human)	CORL2, FUSSEL18
Gene (mouse)	Skor2
Gene synonyms (mouse)	Corl2
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	15
Consensus	nhnSdTTAATTAAbn
GC content	27.41%
Information content (bits; total / per base)	16.213 / 1.081
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	2351

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.991	0.986	0.945	0.939	0.848	0.853
Overall, 2 experiments	best	0.997	0.996	0.993	0.99	0.955	0.949
Methyl HT-SELEX, 1 experiments	median	0.985	0.977	0.897	0.888	0.74	0.756
Methyl HT-SELEX, 1 experiments	best	0.985	0.977	0.897	0.888	0.74	0.756
Non-Methyl HT-SELEX, 1 experiments	median	0.997	0.996	0.993	0.99	0.955	0.949
Non-Methyl HT-SELEX, 1 experiments	best	0.997	0.996	0.993	0.99	0.955	0.949

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.979	0.824	0.933	0.594

TF superclass	Yet undefined DNA-binding domains {0} (TFClass)
TF class	Uncharacterized {0.0} (TFClass)
TF family	Unannotated {0.0.9} (TFClass)
TF subfamily	{0.0.9.0} (TFClass)
TFClass ID	TFClass: 0.0.9.0.4
HGNC	HGNC:32695
MGI	MGI:3645984
EntrezGene (human)	GeneID:652991 (SSTAR profile)
EntrezGene (mouse)	GeneID:664805 (SSTAR profile)
UniProt ID (human)	SKOR2_HUMAN
UniProt ID (mouse)	SKOR2_MOUSE
UniProt AC (human)	Q2VWA4 (TFClass)
UniProt AC (mouse)	A7M7C7 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	SKOR2.H12RSNP.0.SM.B.pcm
PWM	SKOR2.H12RSNP.0.SM.B.pwm
PFM	SKOR2.H12RSNP.0.SM.B.pfm
Alignment	SKOR2.H12RSNP.0.SM.B.words.tsv
Threshold to P-value map	SKOR2.H12RSNP.0.SM.B.thr
Motif in other formats
JASPAR format	SKOR2.H12RSNP.0.SM.B_jaspar_format.txt
MEME format	SKOR2.H12RSNP.0.SM.B_meme_format.meme
Transfac format	SKOR2.H12RSNP.0.SM.B_transfac_format.txt
Homer format	SKOR2.H12RSNP.0.SM.B_homer_format_0.001.txt SKOR2.H12RSNP.0.SM.B_homer_format_0.0005.txt SKOR2.H12RSNP.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	522.5	526.5	578.5	723.5
02	1226.5	314.5	276.5	533.5
03	643.0	510.0	784.0	414.0
04	301.0	1485.0	345.0	220.0
05	363.0	166.0	1080.0	742.0
06	3.0	5.0	849.0	1494.0
07	0.0	0.0	0.0	2351.0
08	2351.0	0.0	0.0	0.0
09	2351.0	0.0	0.0	0.0
10	0.0	0.0	0.0	2351.0
11	0.0	0.0	0.0	2351.0
12	2350.0	0.0	1.0	0.0
13	2323.0	19.0	3.0	6.0
14	163.5	805.5	574.5	807.5
15	554.5	482.5	860.5	453.5

PFM

	A	C	G	T
01	0.222	0.224	0.246	0.308
02	0.522	0.134	0.118	0.227
03	0.274	0.217	0.333	0.176
04	0.128	0.632	0.147	0.094
05	0.154	0.071	0.459	0.316
06	0.001	0.002	0.361	0.635
07	0.0	0.0	0.0	1.0
08	1.0	0.0	0.0	0.0
09	1.0	0.0	0.0	0.0
10	0.0	0.0	0.0	1.0
11	0.0	0.0	0.0	1.0
12	1.0	0.0	0.0	0.0
13	0.988	0.008	0.001	0.003
14	0.07	0.343	0.244	0.343
15	0.236	0.205	0.366	0.193

PWM

	A	C	G	T
01	-0.117	-0.11	-0.016	0.207
02	0.734	-0.622	-0.75	-0.097
03	0.09	-0.141	0.287	-0.349
04	-0.666	0.925	-0.53	-0.977
05	-0.48	-1.256	0.607	0.232
06	-4.782	-4.442	0.367	0.931
07	-5.717	-5.717	-5.717	1.384
08	1.384	-5.717	-5.717	-5.717
09	1.384	-5.717	-5.717	-5.717
10	-5.717	-5.717	-5.717	1.384
11	-5.717	-5.717	-5.717	1.384
12	1.383	-5.717	-5.301	-5.717
13	1.372	-3.338	-4.782	-4.308
14	-1.271	0.314	-0.023	0.317
15	-0.058	-0.197	0.38	-0.258

Standard thresholds

P-value	Threshold
0.001	-1.22614
0.0005	1.73606
0.0001	4.60861