SKOR2.H12CORE.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SKOR2.H12CORE.0.SM.B
Gene (human)	SKOR2 (GeneCards)
Gene synonyms (human)	CORL2, FUSSEL18
Gene (mouse)	Skor2
Gene synonyms (mouse)	Corl2
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	15
Consensus	ndnSdTTAATTAAnn
GC content	28.11%
Information content (bits; total / per base)	16.126 / 1.075
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	7328

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.992	0.988	0.947	0.942	0.859	0.859
Overall, 2 experiments	best	0.998	0.996	0.994	0.991	0.955	0.949
Methyl HT-SELEX, 1 experiments	median	0.986	0.98	0.9	0.892	0.764	0.77
Methyl HT-SELEX, 1 experiments	best	0.986	0.98	0.9	0.892	0.764	0.77
Non-Methyl HT-SELEX, 1 experiments	median	0.998	0.996	0.994	0.991	0.955	0.949
Non-Methyl HT-SELEX, 1 experiments	best	0.998	0.996	0.994	0.991	0.955	0.949

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.97	0.833	0.93	0.615

TF superclass	Yet undefined DNA-binding domains {0} (TFClass)
TF class	Uncharacterized {0.0} (TFClass)
TF family	Unannotated {0.0.9} (TFClass)
TF subfamily	{0.0.9.0} (TFClass)
TFClass ID	TFClass: 0.0.9.0.4
HGNC	HGNC:32695
MGI	MGI:3645984
EntrezGene (human)	GeneID:652991 (SSTAR profile)
EntrezGene (mouse)	GeneID:664805 (SSTAR profile)
UniProt ID (human)	SKOR2_HUMAN
UniProt ID (mouse)	SKOR2_MOUSE
UniProt AC (human)	Q2VWA4 (TFClass)
UniProt AC (mouse)	A7M7C7 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	SKOR2.H12CORE.0.SM.B.pcm
PWM	SKOR2.H12CORE.0.SM.B.pwm
PFM	SKOR2.H12CORE.0.SM.B.pfm
Alignment	SKOR2.H12CORE.0.SM.B.words.tsv
Threshold to P-value map	SKOR2.H12CORE.0.SM.B.thr
Motif in other formats
JASPAR format	SKOR2.H12CORE.0.SM.B_jaspar_format.txt
MEME format	SKOR2.H12CORE.0.SM.B_meme_format.meme
Transfac format	SKOR2.H12CORE.0.SM.B_transfac_format.txt
Homer format	SKOR2.H12CORE.0.SM.B_homer_format_0.001.txt SKOR2.H12CORE.0.SM.B_homer_format_0.0005.txt SKOR2.H12CORE.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1508.75	1720.75	1931.75	2166.75
02	3872.0	938.0	951.0	1567.0
03	2115.0	1493.0	2409.0	1311.0
04	857.0	4700.0	1205.0	566.0
05	1362.0	423.0	2796.0	2747.0
06	0.0	0.0	3417.0	3911.0
07	0.0	0.0	0.0	7328.0
08	7328.0	0.0	0.0	0.0
09	7328.0	0.0	0.0	0.0
10	0.0	0.0	0.0	7328.0
11	0.0	0.0	0.0	7328.0
12	7328.0	0.0	0.0	0.0
13	7239.0	67.0	0.0	22.0
14	1195.75	2618.75	2131.75	1381.75
15	2214.75	1772.75	2318.75	1021.75

PFM

	A	C	G	T
01	0.206	0.235	0.264	0.296
02	0.528	0.128	0.13	0.214
03	0.289	0.204	0.329	0.179
04	0.117	0.641	0.164	0.077
05	0.186	0.058	0.382	0.375
06	0.0	0.0	0.466	0.534
07	0.0	0.0	0.0	1.0
08	1.0	0.0	0.0	0.0
09	1.0	0.0	0.0	0.0
10	0.0	0.0	0.0	1.0
11	0.0	0.0	0.0	1.0
12	1.0	0.0	0.0	0.0
13	0.988	0.009	0.0	0.003
14	0.163	0.357	0.291	0.189
15	0.302	0.242	0.316	0.139

PWM

	A	C	G	T
01	-0.194	-0.063	0.053	0.168
02	0.748	-0.668	-0.655	-0.156
03	0.143	-0.204	0.274	-0.334
04	-0.758	0.941	-0.418	-1.172
05	-0.296	-1.462	0.422	0.405
06	-6.715	-6.715	0.623	0.758
07	-6.715	-6.715	-6.715	1.385
08	1.385	-6.715	-6.715	-6.715
09	1.385	-6.715	-6.715	-6.715
10	-6.715	-6.715	-6.715	1.385
11	-6.715	-6.715	-6.715	1.385
12	1.385	-6.715	-6.715	-6.715
13	1.373	-3.277	-6.715	-4.327
14	-0.426	0.357	0.151	-0.282
15	0.19	-0.033	0.235	-0.583

Standard thresholds

P-value	Threshold
0.001	-2.76899
0.0005	0.79301
0.0001	3.71371