MotifSIX6.H12CORE.0.SM.B
Gene (human)SIX6
(GeneCards)
Gene synonyms (human)OPTX2, SIX9
Gene (mouse)Six6
Gene synonyms (mouse)Optx2, Six9
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length9
ConsensusnYGATAYbn
GC content44.55%
Information content (bits; total / per base)8.528 / 0.948
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9702

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.876 0.821 0.814 0.764 0.723 0.695
best 0.891 0.841 0.831 0.782 0.745 0.713
Methyl HT-SELEX, 1 experiments median 0.861 0.801 0.797 0.745 0.701 0.676
best 0.861 0.801 0.797 0.745 0.701 0.676
Non-Methyl HT-SELEX, 1 experiments median 0.891 0.841 0.831 0.782 0.745 0.713
best 0.891 0.841 0.831 0.782 0.745 0.713
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-SINE {3.1.6} (TFClass)
TF subfamilySIX3-like {3.1.6.2} (TFClass)
TFClass IDTFClass: 3.1.6.2.2
HGNCHGNC:10892
MGIMGI:1341840
EntrezGene (human)GeneID:4990
(SSTAR profile)
EntrezGene (mouse)GeneID:20476
(SSTAR profile)
UniProt ID (human)SIX6_HUMAN
UniProt ID (mouse)SIX6_MOUSE
UniProt AC (human)O95475
(TFClass)
UniProt AC (mouse)Q9QZ28
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
012827.751422.753287.752163.75
02424.253144.25879.255254.25
0323.01.09669.09.0
049671.08.04.019.0
0536.022.01.09643.0
068657.0994.048.03.0
07666.06020.01302.01714.0
081260.53744.53276.51420.5
092018.52690.52384.52608.5
PFM
ACGT
010.2910.1470.3390.223
020.0440.3240.0910.542
030.0020.00.9970.001
040.9970.0010.00.002
050.0040.0020.00.994
060.8920.1020.0050.0
070.0690.620.1340.177
080.130.3860.3380.146
090.2080.2770.2460.269
PWM
ACGT
010.153-0.5330.304-0.114
02-1.7390.259-1.0130.772
03-4.564-6.6021.382-5.37
041.382-5.463-5.955-4.736
05-4.149-4.604-6.6021.379
061.272-0.891-3.877-6.128
07-1.290.908-0.621-0.347
08-0.6540.4340.3-0.534
09-0.1830.104-0.0170.073
Standard thresholds
P-value Threshold
0.001 5.48069
0.0005 6.129505
0.0001 7.26429