MotifSIX4.H12INVIVO.0.P.B
Gene (human)SIX4
(GeneCards)
Gene synonyms (human)
Gene (mouse)Six4
Gene synonyms (mouse)Arec3
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length14
ConsensusWGWAAYnTGAbMCY
GC content43.2%
Information content (bits; total / per base)15.687 / 1.12
Data sourcesChIP-Seq
Aligned words437

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (6) 0.954 0.964 0.941 0.962 0.972 0.973 7.776 8.355 143.276 352.187
Mouse 1 (7) 0.787 0.802 0.742 0.751 0.794 0.8 3.127 3.241 157.62 182.62

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Methyl HT-SELEX, 1 experiments median 0.541 0.527 0.528 0.519 0.518 0.513
best 0.541 0.527 0.528 0.519 0.518 0.513
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-SINE {3.1.6} (TFClass)
TF subfamilySIX4-like {3.1.6.3} (TFClass)
TFClass IDTFClass: 3.1.6.3.1
HGNCHGNC:10890
MGIMGI:106034
EntrezGene (human)GeneID:51804
(SSTAR profile)
EntrezGene (mouse)GeneID:20474
(SSTAR profile)
UniProt ID (human)SIX4_HUMAN
UniProt ID (mouse)SIX4_MOUSE
UniProt AC (human)Q9UIU6
(TFClass)
UniProt AC (mouse)Q61321
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 1 mouse
HT-SELEX 0
Methyl-HT-SELEX 1
PCM
ACGT
0154.07.052.0324.0
022.00.0432.03.0
03171.019.08.0239.0
04419.08.01.09.0
05431.02.02.02.0
063.0258.06.0170.0
07105.0215.012.0105.0
089.047.013.0368.0
0910.01.0420.06.0
10433.03.00.01.0
1126.0223.097.091.0
12285.0114.018.020.0
1317.0348.06.066.0
1424.0280.051.082.0
PFM
ACGT
010.1240.0160.1190.741
020.0050.00.9890.007
030.3910.0430.0180.547
040.9590.0180.0020.021
050.9860.0050.0050.005
060.0070.590.0140.389
070.240.4920.0270.24
080.0210.1080.030.842
090.0230.0020.9610.014
100.9910.0070.00.002
110.0590.510.2220.208
120.6520.2610.0410.046
130.0390.7960.0140.151
140.0550.6410.1170.188
PWM
ACGT
01-0.691-2.565-0.7271.078
02-3.449-4.2891.364-3.199
030.443-1.686-2.4540.775
041.334-2.454-3.783-2.354
051.362-3.449-3.449-3.449
06-3.1990.851-2.690.437
07-0.0390.67-2.103-0.039
08-2.354-0.825-2.0321.205
09-2.263-3.7831.336-2.69
101.367-3.199-4.289-3.783
11-1.3930.707-0.117-0.18
120.950.042-1.736-1.638
13-1.7891.149-2.69-0.495
14-1.4680.933-0.746-0.282
Standard thresholds
P-value Threshold
0.001 2.66261
0.0005 3.88366
0.0001 6.43622