MotifSIX4.H12CORE.1.M.C
Gene (human)SIX4
(GeneCards)
Gene synonyms (human)
Gene (mouse)Six4
Gene synonyms (mouse)Arec3
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
C
Motif length15
ConsensusnvbSATACSYnhhvn
GC content51.67%
Information content (bits; total / per base)9.373 / 0.625
Data sourcesMethyl-HT-SELEX
Aligned words574

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (6) 0.693 0.705 0.514 0.558 0.677 0.68 1.664 1.742 25.602 44.745
Mouse 1 (7) 0.525 0.534 0.358 0.366 0.528 0.539 1.078 1.112 4.585 5.319

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Methyl HT-SELEX, 1 experiments median 0.724 0.662 0.679 0.628 0.636 0.6
best 0.724 0.662 0.679 0.628 0.636 0.6
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-SINE {3.1.6} (TFClass)
TF subfamilySIX4-like {3.1.6.3} (TFClass)
TFClass IDTFClass: 3.1.6.3.1
HGNCHGNC:10890
MGIMGI:106034
EntrezGene (human)GeneID:51804
(SSTAR profile)
EntrezGene (mouse)GeneID:20474
(SSTAR profile)
UniProt ID (human)SIX4_HUMAN
UniProt ID (mouse)SIX4_MOUSE
UniProt AC (human)Q9UIU6
(TFClass)
UniProt AC (mouse)Q61321
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 1 mouse
HT-SELEX 0
Methyl-HT-SELEX 1
PCM
ACGT
01163.0210.0100.0101.0
02205.75114.75177.7575.75
0333.0247.073.0221.0
0469.081.0417.07.0
05513.025.00.036.0
060.0169.00.0405.0
07570.04.00.00.0
080.0574.00.00.0
0938.0280.0245.011.0
1058.0275.025.0216.0
11138.096.0144.0196.0
12206.0213.051.0104.0
13201.0203.083.087.0
14191.5217.592.572.5
15141.75210.75120.75100.75
PFM
ACGT
010.2840.3660.1740.176
020.3580.20.310.132
030.0570.430.1270.385
040.120.1410.7260.012
050.8940.0440.00.063
060.00.2940.00.706
070.9930.0070.00.0
080.01.00.00.0
090.0660.4880.4270.019
100.1010.4790.0440.376
110.240.1670.2510.341
120.3590.3710.0890.181
130.350.3540.1450.152
140.3340.3790.1610.126
150.2470.3670.210.176
PWM
ACGT
010.1260.377-0.356-0.347
020.357-0.2210.212-0.629
03-1.4340.538-0.6650.428
04-0.72-0.5631.06-2.827
051.266-1.697-4.515-1.351
06-4.5150.162-4.5151.03
071.371-3.257-4.515-4.515
08-4.5151.378-4.515-4.515
09-1.2990.6630.53-2.445
10-0.890.645-1.6970.405
11-0.039-0.3970.0030.309
120.3580.391-1.015-0.318
130.3340.344-0.54-0.493
140.2860.412-0.433-0.672
15-0.0120.381-0.171-0.349
Standard thresholds
P-value Threshold
0.001 5.10486
0.0005 5.90441
0.0001 7.35526