| Motif | SIX3.H12INVITRO.0.SM.B |
| Gene (human) | SIX3 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Six3 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | SIX3.H12INVITRO.0.SM.B |
| Gene (human) | SIX3 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Six3 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 9 |
| Consensus | nYGATAYvn |
| GC content | 46.67% |
| Information content (bits; total / per base) | 9.303 / 1.034 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9785 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.919 | 0.876 | 0.87 | 0.824 | 0.777 | 0.748 |
| best | 0.923 | 0.882 | 0.881 | 0.835 | 0.792 | 0.761 | |
| Methyl HT-SELEX, 1 experiments | median | 0.914 | 0.87 | 0.859 | 0.814 | 0.762 | 0.735 |
| best | 0.914 | 0.87 | 0.859 | 0.814 | 0.762 | 0.735 | |
| Non-Methyl HT-SELEX, 1 experiments | median | 0.923 | 0.882 | 0.881 | 0.835 | 0.792 | 0.761 |
| best | 0.923 | 0.882 | 0.881 | 0.835 | 0.792 | 0.761 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | HD-SINE {3.1.6} (TFClass) |
| TF subfamily | SIX3-like {3.1.6.2} (TFClass) |
| TFClass ID | TFClass: 3.1.6.2.1 |
| HGNC | HGNC:10889 |
| MGI | MGI:102764 |
| EntrezGene (human) | GeneID:6496 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:20473 (SSTAR profile) |
| UniProt ID (human) | SIX3_HUMAN |
| UniProt ID (mouse) | SIX3_MOUSE |
| UniProt AC (human) | O95343 (TFClass) |
| UniProt AC (mouse) | Q62233 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 1 |
| PCM | SIX3.H12INVITRO.0.SM.B.pcm |
| PWM | SIX3.H12INVITRO.0.SM.B.pwm |
| PFM | SIX3.H12INVITRO.0.SM.B.pfm |
| Alignment | SIX3.H12INVITRO.0.SM.B.words.tsv |
| Threshold to P-value map | SIX3.H12INVITRO.0.SM.B.thr |
| Motif in other formats | |
| JASPAR format | SIX3.H12INVITRO.0.SM.B_jaspar_format.txt |
| MEME format | SIX3.H12INVITRO.0.SM.B_meme_format.meme |
| Transfac format | SIX3.H12INVITRO.0.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2554.75 | 1868.75 | 3586.75 | 1774.75 |
| 02 | 457.75 | 3204.75 | 610.75 | 5511.75 |
| 03 | 45.0 | 4.0 | 9715.0 | 21.0 |
| 04 | 9784.0 | 0.0 | 0.0 | 1.0 |
| 05 | 5.0 | 23.0 | 0.0 | 9757.0 |
| 06 | 9455.0 | 328.0 | 0.0 | 2.0 |
| 07 | 133.0 | 6550.0 | 1386.0 | 1716.0 |
| 08 | 1128.75 | 3855.75 | 3839.75 | 960.75 |
| 09 | 1512.0 | 3576.0 | 2554.0 | 2143.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.261 | 0.191 | 0.367 | 0.181 |
| 02 | 0.047 | 0.328 | 0.062 | 0.563 |
| 03 | 0.005 | 0.0 | 0.993 | 0.002 |
| 04 | 1.0 | 0.0 | 0.0 | 0.0 |
| 05 | 0.001 | 0.002 | 0.0 | 0.997 |
| 06 | 0.966 | 0.034 | 0.0 | 0.0 |
| 07 | 0.014 | 0.669 | 0.142 | 0.175 |
| 08 | 0.115 | 0.394 | 0.392 | 0.098 |
| 09 | 0.155 | 0.365 | 0.261 | 0.219 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.043 | -0.269 | 0.382 | -0.321 |
| 02 | -1.672 | 0.27 | -1.385 | 0.812 |
| 03 | -3.947 | -5.963 | 1.378 | -4.655 |
| 04 | 1.385 | -6.972 | -6.972 | -6.61 |
| 05 | -5.816 | -4.573 | -6.972 | 1.383 |
| 06 | 1.351 | -2.003 | -6.972 | -6.345 |
| 07 | -2.896 | 0.984 | -0.567 | -0.354 |
| 08 | -0.772 | 0.455 | 0.451 | -0.933 |
| 09 | -0.481 | 0.379 | 0.043 | -0.132 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.42187 |
| 0.0005 | 6.238095 |
| 0.0001 | 7.47223 |