SIX3.H12CORE.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SIX3.H12CORE.0.SM.B
Gene (human)	SIX3 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Six3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	9
Consensus	nYGATAYvn
GC content	46.67%
Information content (bits; total / per base)	9.303 / 1.034
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9785

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.919	0.876	0.87	0.824	0.777	0.748
Overall, 2 experiments	best	0.923	0.882	0.881	0.835	0.792	0.761
Methyl HT-SELEX, 1 experiments	median	0.914	0.87	0.859	0.814	0.762	0.735
Methyl HT-SELEX, 1 experiments	best	0.914	0.87	0.859	0.814	0.762	0.735
Non-Methyl HT-SELEX, 1 experiments	median	0.923	0.882	0.881	0.835	0.792	0.761
Non-Methyl HT-SELEX, 1 experiments	best	0.923	0.882	0.881	0.835	0.792	0.761

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	HD-SINE {3.1.6} (TFClass)
TF subfamily	SIX3-like {3.1.6.2} (TFClass)
TFClass ID	TFClass: 3.1.6.2.1
HGNC	HGNC:10889
MGI	MGI:102764
EntrezGene (human)	GeneID:6496 (SSTAR profile)
EntrezGene (mouse)	GeneID:20473 (SSTAR profile)
UniProt ID (human)	SIX3_HUMAN
UniProt ID (mouse)	SIX3_MOUSE
UniProt AC (human)	O95343 (TFClass)
UniProt AC (mouse)	Q62233 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	SIX3.H12CORE.0.SM.B.pcm
PWM	SIX3.H12CORE.0.SM.B.pwm
PFM	SIX3.H12CORE.0.SM.B.pfm
Alignment	SIX3.H12CORE.0.SM.B.words.tsv
Threshold to P-value map	SIX3.H12CORE.0.SM.B.thr
Motif in other formats
JASPAR format	SIX3.H12CORE.0.SM.B_jaspar_format.txt
MEME format	SIX3.H12CORE.0.SM.B_meme_format.meme
Transfac format	SIX3.H12CORE.0.SM.B_transfac_format.txt
Homer format	SIX3.H12CORE.0.SM.B_homer_format_0.001.txt SIX3.H12CORE.0.SM.B_homer_format_0.0005.txt SIX3.H12CORE.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2554.75	1868.75	3586.75	1774.75
02	457.75	3204.75	610.75	5511.75
03	45.0	4.0	9715.0	21.0
04	9784.0	0.0	0.0	1.0
05	5.0	23.0	0.0	9757.0
06	9455.0	328.0	0.0	2.0
07	133.0	6550.0	1386.0	1716.0
08	1128.75	3855.75	3839.75	960.75
09	1512.0	3576.0	2554.0	2143.0

PFM

	A	C	G	T
01	0.261	0.191	0.367	0.181
02	0.047	0.328	0.062	0.563
03	0.005	0.0	0.993	0.002
04	1.0	0.0	0.0	0.0
05	0.001	0.002	0.0	0.997
06	0.966	0.034	0.0	0.0
07	0.014	0.669	0.142	0.175
08	0.115	0.394	0.392	0.098
09	0.155	0.365	0.261	0.219

PWM

	A	C	G	T
01	0.043	-0.269	0.382	-0.321
02	-1.672	0.27	-1.385	0.812
03	-3.947	-5.963	1.378	-4.655
04	1.385	-6.972	-6.972	-6.61
05	-5.816	-4.573	-6.972	1.383
06	1.351	-2.003	-6.972	-6.345
07	-2.896	0.984	-0.567	-0.354
08	-0.772	0.455	0.451	-0.933
09	-0.481	0.379	0.043	-0.132

Standard thresholds

P-value	Threshold
0.001	5.42187
0.0005	6.238095
0.0001	7.47223