MotifSIX3.H12CORE.0.SM.B
Gene (human)SIX3
(GeneCards)
Gene synonyms (human)
Gene (mouse)Six3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length9
ConsensusnYGATAYvn
GC content46.67%
Information content (bits; total / per base)9.303 / 1.034
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9785

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.919 0.876 0.87 0.824 0.777 0.748
best 0.923 0.882 0.881 0.835 0.792 0.761
Methyl HT-SELEX, 1 experiments median 0.914 0.87 0.859 0.814 0.762 0.735
best 0.914 0.87 0.859 0.814 0.762 0.735
Non-Methyl HT-SELEX, 1 experiments median 0.923 0.882 0.881 0.835 0.792 0.761
best 0.923 0.882 0.881 0.835 0.792 0.761
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-SINE {3.1.6} (TFClass)
TF subfamilySIX3-like {3.1.6.2} (TFClass)
TFClass IDTFClass: 3.1.6.2.1
HGNCHGNC:10889
MGIMGI:102764
EntrezGene (human)GeneID:6496
(SSTAR profile)
EntrezGene (mouse)GeneID:20473
(SSTAR profile)
UniProt ID (human)SIX3_HUMAN
UniProt ID (mouse)SIX3_MOUSE
UniProt AC (human)O95343
(TFClass)
UniProt AC (mouse)Q62233
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
012554.751868.753586.751774.75
02457.753204.75610.755511.75
0345.04.09715.021.0
049784.00.00.01.0
055.023.00.09757.0
069455.0328.00.02.0
07133.06550.01386.01716.0
081128.753855.753839.75960.75
091512.03576.02554.02143.0
PFM
ACGT
010.2610.1910.3670.181
020.0470.3280.0620.563
030.0050.00.9930.002
041.00.00.00.0
050.0010.0020.00.997
060.9660.0340.00.0
070.0140.6690.1420.175
080.1150.3940.3920.098
090.1550.3650.2610.219
PWM
ACGT
010.043-0.2690.382-0.321
02-1.6720.27-1.3850.812
03-3.947-5.9631.378-4.655
041.385-6.972-6.972-6.61
05-5.816-4.573-6.9721.383
061.351-2.003-6.972-6.345
07-2.8960.984-0.567-0.354
08-0.7720.4550.451-0.933
09-0.4810.3790.043-0.132
Standard thresholds
P-value Threshold
0.001 5.42187
0.0005 6.238095
0.0001 7.47223