MotifSIX1.H12INVITRO.0.P.B
Gene (human)SIX1
(GeneCards)
Gene synonyms (human)
Gene (mouse)Six1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length14
ConsensusKGWAAYhKGAYMYb
GC content39.95%
Information content (bits; total / per base)12.668 / 0.905
Data sourcesChIP-Seq
Aligned words145

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (18) 0.928 0.942 0.873 0.901 0.924 0.943 4.101 4.672 262.77 331.553

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.72 0.691 0.651 0.63 0.59 0.587
best 0.87 0.847 0.733 0.723 0.645 0.642
Methyl HT-SELEX, 2 experiments median 0.72 0.696 0.64 0.627 0.58 0.581
best 0.87 0.847 0.732 0.723 0.632 0.64
Non-Methyl HT-SELEX, 2 experiments median 0.72 0.691 0.651 0.63 0.597 0.588
best 0.85 0.825 0.733 0.715 0.645 0.642

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.729 0.47 0.788 0.625
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-SINE {3.1.6} (TFClass)
TF subfamilySIX1-like {3.1.6.1} (TFClass)
TFClass IDTFClass: 3.1.6.1.1
HGNCHGNC:10887
MGIMGI:102780
EntrezGene (human)GeneID:6495
(SSTAR profile)
EntrezGene (mouse)GeneID:20471
(SSTAR profile)
UniProt ID (human)SIX1_HUMAN
UniProt ID (mouse)SIX1_MOUSE
UniProt AC (human)Q15475
(TFClass)
UniProt AC (mouse)Q62231
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
0126.02.030.087.0
022.02.0139.02.0
0353.05.04.083.0
04133.04.01.07.0
05140.01.02.02.0
064.089.08.044.0
0732.059.010.044.0
088.011.020.0106.0
0918.02.0123.02.0
10142.00.01.02.0
116.029.027.083.0
1272.065.06.02.0
1312.069.06.058.0
1413.062.034.036.0
PFM
ACGT
010.1790.0140.2070.6
020.0140.0140.9590.014
030.3660.0340.0280.572
040.9170.0280.0070.048
050.9660.0070.0140.014
060.0280.6140.0550.303
070.2210.4070.0690.303
080.0550.0760.1380.731
090.1240.0140.8480.014
100.9790.00.0070.014
110.0410.20.1860.572
120.4970.4480.0410.014
130.0830.4760.0410.4
140.090.4280.2340.248
PWM
ACGT
01-0.319-2.447-0.1820.856
02-2.447-2.4471.319-2.447
030.369-1.793-1.9670.81
041.275-1.967-2.816-1.515
051.326-2.816-2.447-2.447
06-1.9670.878-1.40.188
07-0.120.474-1.2040.188
08-1.4-1.119-0.5681.051
09-0.667-2.4471.198-2.447
101.34-3.406-2.816-2.447
11-1.644-0.215-0.2830.81
120.670.569-1.644-2.447
13-1.0410.628-1.6440.457
14-0.9680.523-0.062-0.007
Standard thresholds
P-value Threshold
0.001 4.23191
0.0005 5.17826
0.0001 7.14796