MotifSHOX2.H12INVITRO.0.S.B
Gene (human)SHOX2
(GeneCards)
Gene synonyms (human)OG12X, SHOT
Gene (mouse)Shox2
Gene synonyms (mouse)Og12x, Prx3
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length18
ConsensushWWWWddvYTAATTASbn
GC content28.38%
Information content (bits; total / per base)15.551 / 0.864
Data sourcesHT-SELEX
Aligned words6592

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 4 experiments median 0.997 0.995 0.993 0.989 0.942 0.944
best 0.999 0.999 0.998 0.998 0.996 0.995
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilySHOX {3.1.3.25} (TFClass)
TFClass IDTFClass: 3.1.3.25.2
HGNCHGNC:10854
MGIMGI:1201673
EntrezGene (human)GeneID:6474
(SSTAR profile)
EntrezGene (mouse)GeneID:20429
(SSTAR profile)
UniProt ID (human)SHOX2_HUMAN
UniProt ID (mouse)SHOX2_MOUSE
UniProt AC (human)O60902
(TFClass)
UniProt AC (mouse)P70390
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 4
Methyl-HT-SELEX 0
PCM
ACGT
012612.0943.0572.02465.0
023066.25259.25150.253116.25
033597.025.0107.02863.0
043354.060.0265.02913.0
051819.0212.0919.03642.0
061239.0549.01783.03021.0
071937.0928.02470.01257.0
082289.0947.02675.0681.0
0931.03658.0910.01993.0
100.01919.00.04673.0
116592.00.00.00.0
126592.00.00.00.0
130.00.00.06592.0
140.00.00.06592.0
155978.00.0614.00.0
161144.01346.04067.035.0
17804.252803.251626.251358.25
181645.252210.251653.251083.25
PFM
ACGT
010.3960.1430.0870.374
020.4650.0390.0230.473
030.5460.0040.0160.434
040.5090.0090.040.442
050.2760.0320.1390.552
060.1880.0830.270.458
070.2940.1410.3750.191
080.3470.1440.4060.103
090.0050.5550.1380.302
100.00.2910.00.709
111.00.00.00.0
121.00.00.00.0
130.00.00.01.0
140.00.00.01.0
150.9070.00.0930.0
160.1740.2040.6170.005
170.1220.4250.2470.206
180.250.3350.2510.164
PWM
ACGT
010.46-0.557-1.0560.402
020.62-1.842-2.3820.636
030.78-4.105-2.7150.552
040.71-3.278-1.8210.569
050.099-2.042-0.5830.792
06-0.285-1.0970.0790.605
070.161-0.5730.404-0.27
080.328-0.5530.484-0.882
09-3.9060.797-0.5930.19
10-6.6210.152-6.6211.041
111.385-6.621-6.621-6.621
121.385-6.621-6.621-6.621
13-6.621-6.621-6.6211.385
14-6.621-6.621-6.6211.385
151.288-6.621-0.985-6.621
16-0.364-0.2020.903-3.792
17-0.7160.531-0.013-0.193
18-0.0020.2930.003-0.419
Standard thresholds
P-value Threshold
0.001 0.16921
0.0005 1.93306
0.0001 5.96231