MotifSHOX.H12INVITRO.1.S.B
Gene (human)SHOX
(GeneCards)
Gene synonyms (human)PHOG
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length13
ConsensusnvvbTAATTRvhh
GC content33.48%
Information content (bits; total / per base)12.103 / 0.931
Data sourcesHT-SELEX
Aligned words9555

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.986 0.974 0.98 0.966 0.953 0.939
best 0.991 0.983 0.985 0.976 0.972 0.958
Methyl HT-SELEX, 1 experiments median 0.989 0.98 0.984 0.973 0.972 0.958
best 0.989 0.98 0.984 0.973 0.972 0.958
Non-Methyl HT-SELEX, 3 experiments median 0.982 0.969 0.976 0.959 0.944 0.936
best 0.991 0.983 0.985 0.976 0.962 0.942

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.777 0.636 0.774 0.575
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilySHOX {3.1.3.25} (TFClass)
TFClass IDTFClass: 3.1.3.25.1
HGNCHGNC:10853
MGI
EntrezGene (human)GeneID:6473
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)SHOX_HUMAN
UniProt ID (mouse)
UniProt AC (human)O15266
(TFClass)
UniProt AC (mouse)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012675.252248.252265.252366.25
022113.53542.52776.51122.5
031674.03905.03367.0609.0
04301.04813.02196.02245.0
050.00.00.09555.0
069555.00.00.00.0
079555.00.00.00.0
080.00.00.09555.0
090.032.028.09495.0
105497.060.03947.051.0
113806.01664.03622.0463.0
122398.02470.01127.03560.0
131844.251830.251694.254186.25
PFM
ACGT
010.280.2350.2370.248
020.2210.3710.2910.117
030.1750.4090.3520.064
040.0320.5040.230.235
050.00.00.01.0
061.00.00.00.0
071.00.00.00.0
080.00.00.01.0
090.00.0030.0030.994
100.5750.0060.4130.005
110.3980.1740.3790.048
120.2510.2590.1180.373
130.1930.1920.1770.438
PWM
ACGT
010.113-0.061-0.053-0.009
02-0.1220.3940.15-0.754
03-0.3550.4910.343-1.364
04-2.0650.7-0.084-0.062
05-6.95-6.95-6.951.386
061.386-6.95-6.95-6.95
071.386-6.95-6.95-6.95
08-6.95-6.95-6.951.386
09-6.95-4.245-4.3691.379
100.833-3.6480.502-3.804
110.465-0.3610.416-1.637
120.0040.033-0.750.399
13-0.258-0.266-0.3430.561
Standard thresholds
P-value Threshold
0.001 2.039865
0.0005 4.13396
0.0001 7.95602