| Motif | RXRG.H12INVIVO.2.P.B |
| Gene (human) | RXRG (GeneCards) |
| Gene synonyms (human) | NR2B3 |
| Gene (mouse) | Rxrg |
| Gene synonyms (mouse) | Nr2b3 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 2 |
| Quality | B |
| Motif | RXRG.H12INVIVO.2.P.B |
| Gene (human) | RXRG (GeneCards) |
| Gene synonyms (human) | NR2B3 |
| Gene (mouse) | Rxrg |
| Gene synonyms (mouse) | Nr2b3 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 2 |
| Quality | B |
| Motif length | 22 |
| Consensus | vRddvdhbndRAGKTCAvRRhh |
| GC content | 52.34% |
| Information content (bits; total / per base) | 12.888 / 0.586 |
| Data sources | ChIP-Seq |
| Aligned words | 101 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mouse | 3 (14) | 0.722 | 0.944 | 0.635 | 0.879 | 0.708 | 0.965 | 3.344 | 6.174 | 37.032 | 202.31 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 5 experiments | median | 0.963 | 0.94 | 0.913 | 0.888 | 0.786 | 0.781 |
| best | 0.973 | 0.953 | 0.961 | 0.937 | 0.932 | 0.903 | |
| Methyl HT-SELEX, 1 experiments | median | 0.973 | 0.953 | 0.961 | 0.937 | 0.932 | 0.903 |
| best | 0.973 | 0.953 | 0.961 | 0.937 | 0.932 | 0.903 | |
| Non-Methyl HT-SELEX, 4 experiments | median | 0.962 | 0.94 | 0.899 | 0.875 | 0.765 | 0.764 |
| best | 0.965 | 0.945 | 0.939 | 0.909 | 0.873 | 0.845 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.56 | 0.099 | -0.073 | 0.052 |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | Nuclear receptors with C4 zinc fingers {2.1} (TFClass) |
| TF family | RXR-related receptors {2.1.3} (TFClass) |
| TF subfamily | RXR (NR2B) {2.1.3.1} (TFClass) |
| TFClass ID | TFClass: 2.1.3.1.3 |
| HGNC | HGNC:10479 |
| MGI | MGI:98216 |
| EntrezGene (human) | GeneID:6258 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:20183 (SSTAR profile) |
| UniProt ID (human) | RXRG_HUMAN |
| UniProt ID (mouse) | RXRG_MOUSE |
| UniProt AC (human) | P48443 (TFClass) |
| UniProt AC (mouse) | P28705 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 3 mouse |
| HT-SELEX | 4 |
| Methyl-HT-SELEX | 1 |
| PCM | RXRG.H12INVIVO.2.P.B.pcm |
| PWM | RXRG.H12INVIVO.2.P.B.pwm |
| PFM | RXRG.H12INVIVO.2.P.B.pfm |
| Alignment | RXRG.H12INVIVO.2.P.B.words.tsv |
| Threshold to P-value map | RXRG.H12INVIVO.2.P.B.thr |
| Motif in other formats | |
| JASPAR format | RXRG.H12INVIVO.2.P.B_jaspar_format.txt |
| MEME format | RXRG.H12INVIVO.2.P.B_meme_format.meme |
| Transfac format | RXRG.H12INVIVO.2.P.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 44.0 | 16.0 | 33.0 | 8.0 |
| 02 | 14.0 | 13.0 | 62.0 | 12.0 |
| 03 | 19.0 | 5.0 | 51.0 | 26.0 |
| 04 | 15.0 | 13.0 | 29.0 | 44.0 |
| 05 | 13.0 | 36.0 | 45.0 | 7.0 |
| 06 | 52.0 | 4.0 | 30.0 | 15.0 |
| 07 | 22.0 | 17.0 | 11.0 | 51.0 |
| 08 | 11.0 | 42.0 | 34.0 | 14.0 |
| 09 | 34.0 | 23.0 | 26.0 | 18.0 |
| 10 | 48.0 | 7.0 | 18.0 | 28.0 |
| 11 | 37.0 | 6.0 | 50.0 | 8.0 |
| 12 | 76.0 | 1.0 | 21.0 | 3.0 |
| 13 | 1.0 | 3.0 | 96.0 | 1.0 |
| 14 | 0.0 | 3.0 | 61.0 | 37.0 |
| 15 | 1.0 | 7.0 | 4.0 | 89.0 |
| 16 | 0.0 | 96.0 | 4.0 | 1.0 |
| 17 | 99.0 | 2.0 | 0.0 | 0.0 |
| 18 | 50.0 | 16.0 | 25.0 | 10.0 |
| 19 | 20.0 | 13.0 | 59.0 | 9.0 |
| 20 | 19.0 | 9.0 | 60.0 | 13.0 |
| 21 | 18.0 | 34.0 | 13.0 | 36.0 |
| 22 | 19.0 | 54.0 | 11.0 | 17.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.436 | 0.158 | 0.327 | 0.079 |
| 02 | 0.139 | 0.129 | 0.614 | 0.119 |
| 03 | 0.188 | 0.05 | 0.505 | 0.257 |
| 04 | 0.149 | 0.129 | 0.287 | 0.436 |
| 05 | 0.129 | 0.356 | 0.446 | 0.069 |
| 06 | 0.515 | 0.04 | 0.297 | 0.149 |
| 07 | 0.218 | 0.168 | 0.109 | 0.505 |
| 08 | 0.109 | 0.416 | 0.337 | 0.139 |
| 09 | 0.337 | 0.228 | 0.257 | 0.178 |
| 10 | 0.475 | 0.069 | 0.178 | 0.277 |
| 11 | 0.366 | 0.059 | 0.495 | 0.079 |
| 12 | 0.752 | 0.01 | 0.208 | 0.03 |
| 13 | 0.01 | 0.03 | 0.95 | 0.01 |
| 14 | 0.0 | 0.03 | 0.604 | 0.366 |
| 15 | 0.01 | 0.069 | 0.04 | 0.881 |
| 16 | 0.0 | 0.95 | 0.04 | 0.01 |
| 17 | 0.98 | 0.02 | 0.0 | 0.0 |
| 18 | 0.495 | 0.158 | 0.248 | 0.099 |
| 19 | 0.198 | 0.129 | 0.584 | 0.089 |
| 20 | 0.188 | 0.089 | 0.594 | 0.129 |
| 21 | 0.178 | 0.337 | 0.129 | 0.356 |
| 22 | 0.188 | 0.535 | 0.109 | 0.168 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.537 | -0.431 | 0.257 | -1.059 |
| 02 | -0.555 | -0.624 | 0.872 | -0.697 |
| 03 | -0.27 | -1.456 | 0.681 | 0.028 |
| 04 | -0.491 | -0.624 | 0.133 | 0.537 |
| 05 | -0.624 | 0.342 | 0.558 | -1.175 |
| 06 | 0.7 | -1.634 | 0.165 | -0.491 |
| 07 | -0.131 | -0.375 | -0.776 | 0.681 |
| 08 | -0.776 | 0.491 | 0.286 | -0.555 |
| 09 | 0.286 | -0.089 | 0.028 | -0.321 |
| 10 | 0.621 | -1.175 | -0.321 | 0.099 |
| 11 | 0.368 | -1.306 | 0.661 | -1.059 |
| 12 | 1.072 | -2.506 | -0.175 | -1.849 |
| 13 | -2.506 | -1.849 | 1.303 | -2.506 |
| 14 | -3.13 | -1.849 | 0.856 | 0.368 |
| 15 | -2.506 | -1.175 | -1.634 | 1.228 |
| 16 | -3.13 | 1.303 | -1.634 | -2.506 |
| 17 | 1.333 | -2.125 | -3.13 | -3.13 |
| 18 | 0.661 | -0.431 | -0.01 | -0.862 |
| 19 | -0.222 | -0.624 | 0.823 | -0.956 |
| 20 | -0.27 | -0.956 | 0.84 | -0.624 |
| 21 | -0.321 | 0.286 | -0.624 | 0.342 |
| 22 | -0.27 | 0.737 | -0.776 | -0.375 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.31931 |
| 0.0005 | 5.22341 |
| 0.0001 | 7.10716 |