MotifRXRG.H12INVIVO.1.SM.B
Gene (human)RXRG
(GeneCards)
Gene synonyms (human)NR2B3
Gene (mouse)Rxrg
Gene synonyms (mouse)Nr2b3
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length16
ConsensusvRGKKYARAGGTCAnv
GC content50.82%
Information content (bits; total / per base)15.032 / 0.939
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9949

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 3 (14) 0.693 0.901 0.574 0.792 0.633 0.87 1.914 3.066 33.965 139.432

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 5 experiments median 0.999 0.999 0.997 0.996 0.904 0.911
best 1.0 1.0 0.998 0.998 0.99 0.986
Methyl HT-SELEX, 1 experiments median 0.999 0.999 0.997 0.996 0.99 0.986
best 0.999 0.999 0.997 0.996 0.99 0.986
Non-Methyl HT-SELEX, 4 experiments median 1.0 1.0 0.992 0.991 0.871 0.883
best 1.0 1.0 0.998 0.998 0.969 0.965

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.661 0.333 0.783 0.533
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyRXR-related receptors {2.1.3} (TFClass)
TF subfamilyRXR (NR2B) {2.1.3.1} (TFClass)
TFClass IDTFClass: 2.1.3.1.3
HGNCHGNC:10479
MGIMGI:98216
EntrezGene (human)GeneID:6258
(SSTAR profile)
EntrezGene (mouse)GeneID:20183
(SSTAR profile)
UniProt ID (human)RXRG_HUMAN
UniProt ID (mouse)RXRG_MOUSE
UniProt AC (human)P48443
(TFClass)
UniProt AC (mouse)P28705
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 3 mouse
HT-SELEX 4
Methyl-HT-SELEX 1
PCM
ACGT
013315.751540.753693.751398.75
024456.75823.754106.75561.75
03618.0588.08126.0617.0
04475.0543.07436.01495.0
05313.01042.01268.07326.0
06823.06709.01092.01325.0
078515.0504.0445.0485.0
087837.0177.01272.0663.0
098555.031.01355.08.0
109.030.09868.042.0
1145.012.09476.0416.0
1226.083.0481.09359.0
13251.07948.0630.01120.0
148470.0186.01158.0135.0
152946.752743.751259.752998.75
162517.752109.754151.751169.75
PFM
ACGT
010.3330.1550.3710.141
020.4480.0830.4130.056
030.0620.0590.8170.062
040.0480.0550.7470.15
050.0310.1050.1270.736
060.0830.6740.110.133
070.8560.0510.0450.049
080.7880.0180.1280.067
090.860.0030.1360.001
100.0010.0030.9920.004
110.0050.0010.9520.042
120.0030.0080.0480.941
130.0250.7990.0630.113
140.8510.0190.1160.014
150.2960.2760.1270.301
160.2530.2120.4170.118
PWM
ACGT
010.287-0.4780.395-0.575
020.583-1.1030.501-1.485
03-1.39-1.4391.183-1.391
04-1.652-1.5191.095-0.508
05-2.066-0.869-0.6731.08
06-1.1040.992-0.822-0.629
071.23-1.593-1.717-1.631
081.147-2.631-0.67-1.32
091.235-4.314-0.607-5.488
10-5.395-4.3451.377-4.029
11-3.963-5.161.337-1.784
12-4.477-3.374-1.6391.324
13-2.2851.161-1.37-0.797
141.225-2.582-0.763-2.898
150.1690.098-0.6790.187
160.012-0.1640.512-0.753
Standard thresholds
P-value Threshold
0.001 2.98826
0.0005 4.15031
0.0001 6.55081