MotifRUNX3.H12CORE.0.P.B
Gene (human)RUNX3
(GeneCards)
Gene synonyms (human)AML2, CBFA3, PEBP2A3
Gene (mouse)Runx3
Gene synonyms (mouse)Aml2, Cbfa3, Pebp2a3
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusbbhTGYGGTYd
GC content53.07%
Information content (bits; total / per base)10.827 / 0.984
Data sourcesChIP-Seq
Aligned words997

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.918 0.929 0.834 0.858 0.895 0.908 3.205 3.341 308.538 362.018
Mouse 15 (95) 0.892 0.951 0.792 0.902 0.878 0.941 3.02 3.724 172.432 270.745

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 5 experiments median 0.743 0.703 0.624 0.618 0.562 0.571
best 0.96 0.931 0.844 0.833 0.671 0.702

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 12.917 6.325 0.437 0.43
TF superclassImmunoglobulin fold {6} (TFClass)
TF classRunt domain factors {6.4} (TFClass)
TF familyRunt-related {6.4.1} (TFClass)
TF subfamily {6.4.1.0} (TFClass)
TFClass IDTFClass: 6.4.1.0.3
HGNCHGNC:10473
MGIMGI:102672
EntrezGene (human)GeneID:864
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)RUNX3_HUMAN
UniProt ID (mouse)RUNX3_MOUSE
UniProt AC (human)Q13761
(TFClass)
UniProt AC (mouse)Q64131
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 15 mouse
HT-SELEX 5
Methyl-HT-SELEX 0
PCM
ACGT
01158.0225.0394.0220.0
0297.0245.0352.0303.0
03116.0531.072.0278.0
0429.014.04.0950.0
056.011.0966.014.0
0618.0247.023.0709.0
071.02.0994.00.0
083.00.0991.03.0
094.0134.030.0829.0
1058.0221.093.0625.0
11302.048.0223.0424.0
PFM
ACGT
010.1580.2260.3950.221
020.0970.2460.3530.304
030.1160.5330.0720.279
040.0290.0140.0040.953
050.0060.0110.9690.014
060.0180.2480.0230.711
070.0010.0020.9970.0
080.0030.00.9940.003
090.0040.1340.030.831
100.0580.2220.0930.627
110.3030.0480.2240.425
PWM
ACGT
01-0.452-0.1020.455-0.124
02-0.933-0.0170.3430.194
03-0.7570.753-1.2250.108
04-2.1-2.77-3.781.333
05-3.481-2.9821.35-2.77
06-2.543-0.009-2.3171.041
07-4.522-4.211.378-4.979
08-3.972-4.9791.375-3.972
09-3.78-0.615-2.0681.197
10-1.436-0.119-0.9740.915
110.191-1.619-0.110.528
Standard thresholds
P-value Threshold
0.001 4.468075
0.0005 5.529175
0.0001 7.5674