| Motif | RUNX1.H12CORE.0.P.B |
| Gene (human) | RUNX1 (GeneCards) |
| Gene synonyms (human) | AML1, CBFA2 |
| Gene (mouse) | Runx1 |
| Gene synonyms (mouse) | Aml1, Cbfa2, Pebp2ab |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | RUNX1.H12CORE.0.P.B |
| Gene (human) | RUNX1 (GeneCards) |
| Gene synonyms (human) | AML1, CBFA2 |
| Gene (mouse) | Runx1 |
| Gene synonyms (mouse) | Aml1, Cbfa2, Pebp2ab |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 10 |
| Consensus | bYTGYGGTYd |
| GC content | 51.62% |
| Information content (bits; total / per base) | 11.762 / 1.176 |
| Data sources | ChIP-Seq |
| Aligned words | 1002 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 47 (295) | 0.885 | 0.955 | 0.796 | 0.919 | 0.87 | 0.948 | 3.118 | 3.933 | 170.114 | 530.06 |
| Mouse | 42 (254) | 0.863 | 0.973 | 0.774 | 0.936 | 0.839 | 0.962 | 2.858 | 4.062 | 131.094 | 500.678 |
| TF superclass | Immunoglobulin fold {6} (TFClass) |
| TF class | Runt domain factors {6.4} (TFClass) |
| TF family | Runt-related {6.4.1} (TFClass) |
| TF subfamily | {6.4.1.0} (TFClass) |
| TFClass ID | TFClass: 6.4.1.0.2 |
| HGNC | HGNC:10471 |
| MGI | MGI:99852 |
| EntrezGene (human) | GeneID:861 (SSTAR profile) |
| EntrezGene (mouse) | |
| UniProt ID (human) | RUNX1_HUMAN |
| UniProt ID (mouse) | RUNX1_MOUSE |
| UniProt AC (human) | Q01196 (TFClass) |
| UniProt AC (mouse) | Q03347 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 47 human, 42 mouse |
| HT-SELEX | 0 |
| Methyl-HT-SELEX | 0 |
| PCM | RUNX1.H12CORE.0.P.B.pcm |
| PWM | RUNX1.H12CORE.0.P.B.pwm |
| PFM | RUNX1.H12CORE.0.P.B.pfm |
| Alignment | RUNX1.H12CORE.0.P.B.words.tsv |
| Threshold to P-value map | RUNX1.H12CORE.0.P.B.thr |
| Motif in other formats | |
| JASPAR format | RUNX1.H12CORE.0.P.B_jaspar_format.txt |
| MEME format | RUNX1.H12CORE.0.P.B_meme_format.meme |
| Transfac format | RUNX1.H12CORE.0.P.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 90.0 | 292.0 | 324.0 | 296.0 |
| 02 | 82.0 | 514.0 | 46.0 | 360.0 |
| 03 | 2.0 | 15.0 | 7.0 | 978.0 |
| 04 | 0.0 | 1.0 | 998.0 | 3.0 |
| 05 | 9.0 | 350.0 | 2.0 | 641.0 |
| 06 | 3.0 | 3.0 | 993.0 | 3.0 |
| 07 | 1.0 | 2.0 | 998.0 | 1.0 |
| 08 | 1.0 | 42.0 | 39.0 | 920.0 |
| 09 | 18.0 | 240.0 | 68.0 | 676.0 |
| 10 | 308.0 | 50.0 | 188.0 | 456.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.09 | 0.291 | 0.323 | 0.295 |
| 02 | 0.082 | 0.513 | 0.046 | 0.359 |
| 03 | 0.002 | 0.015 | 0.007 | 0.976 |
| 04 | 0.0 | 0.001 | 0.996 | 0.003 |
| 05 | 0.009 | 0.349 | 0.002 | 0.64 |
| 06 | 0.003 | 0.003 | 0.991 | 0.003 |
| 07 | 0.001 | 0.002 | 0.996 | 0.001 |
| 08 | 0.001 | 0.042 | 0.039 | 0.918 |
| 09 | 0.018 | 0.24 | 0.068 | 0.675 |
| 10 | 0.307 | 0.05 | 0.188 | 0.455 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -1.012 | 0.152 | 0.256 | 0.166 |
| 02 | -1.103 | 0.715 | -1.665 | 0.361 |
| 03 | -4.215 | -2.713 | -3.364 | 1.357 |
| 04 | -4.984 | -4.527 | 1.377 | -3.977 |
| 05 | -3.158 | 0.333 | -4.215 | 0.935 |
| 06 | -3.977 | -3.977 | 1.372 | -3.977 |
| 07 | -4.527 | -4.215 | 1.377 | -4.527 |
| 08 | -4.527 | -1.752 | -1.823 | 1.296 |
| 09 | -2.548 | -0.043 | -1.286 | 0.988 |
| 10 | 0.205 | -1.584 | -0.285 | 0.596 |
| P-value | Threshold |
|---|---|
| 0.001 | 3.919605 |
| 0.0005 | 5.07613 |
| 0.0001 | 7.578495 |