MotifRUNX1.H12CORE.0.P.B
Gene (human)RUNX1
(GeneCards)
Gene synonyms (human)AML1, CBFA2
Gene (mouse)Runx1
Gene synonyms (mouse)Aml1, Cbfa2, Pebp2ab
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length10
ConsensusbYTGYGGTYd
GC content51.62%
Information content (bits; total / per base)11.762 / 1.176
Data sourcesChIP-Seq
Aligned words1002

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 47 (295) 0.885 0.955 0.796 0.919 0.87 0.948 3.118 3.933 170.114 530.06
Mouse 42 (254) 0.863 0.973 0.774 0.936 0.839 0.962 2.858 4.062 131.094 500.678
TF superclassImmunoglobulin fold {6} (TFClass)
TF classRunt domain factors {6.4} (TFClass)
TF familyRunt-related {6.4.1} (TFClass)
TF subfamily {6.4.1.0} (TFClass)
TFClass IDTFClass: 6.4.1.0.2
HGNCHGNC:10471
MGIMGI:99852
EntrezGene (human)GeneID:861
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)RUNX1_HUMAN
UniProt ID (mouse)RUNX1_MOUSE
UniProt AC (human)Q01196
(TFClass)
UniProt AC (mouse)Q03347
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 47 human, 42 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
0190.0292.0324.0296.0
0282.0514.046.0360.0
032.015.07.0978.0
040.01.0998.03.0
059.0350.02.0641.0
063.03.0993.03.0
071.02.0998.01.0
081.042.039.0920.0
0918.0240.068.0676.0
10308.050.0188.0456.0
PFM
ACGT
010.090.2910.3230.295
020.0820.5130.0460.359
030.0020.0150.0070.976
040.00.0010.9960.003
050.0090.3490.0020.64
060.0030.0030.9910.003
070.0010.0020.9960.001
080.0010.0420.0390.918
090.0180.240.0680.675
100.3070.050.1880.455
PWM
ACGT
01-1.0120.1520.2560.166
02-1.1030.715-1.6650.361
03-4.215-2.713-3.3641.357
04-4.984-4.5271.377-3.977
05-3.1580.333-4.2150.935
06-3.977-3.9771.372-3.977
07-4.527-4.2151.377-4.527
08-4.527-1.752-1.8231.296
09-2.548-0.043-1.2860.988
100.205-1.584-0.2850.596
Standard thresholds
P-value Threshold
0.001 3.919605
0.0005 5.07613
0.0001 7.578495