MotifRORG.H12INVIVO.1.PS.A
Gene (human)RORC
(GeneCards)
Gene synonyms (human)NR1F3, RORG, RZRG
Gene (mouse)Rorc
Gene synonyms (mouse)Nr1f3, Rorg, Thor
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length12
ConsensusddAAbTRGGKCA
GC content43.24%
Information content (bits; total / per base)12.56 / 1.047
Data sourcesChIP-Seq + HT-SELEX
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 7 (44) 0.724 0.942 0.712 0.937 0.708 0.944 3.617 5.839 50.885 297.119

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.995 0.991 0.987 0.981 0.952 0.942
best 0.996 0.994 0.989 0.984 0.957 0.945
Methyl HT-SELEX, 1 experiments median 0.996 0.994 0.989 0.984 0.946 0.938
best 0.996 0.994 0.989 0.984 0.946 0.938
Non-Methyl HT-SELEX, 1 experiments median 0.993 0.989 0.986 0.978 0.957 0.945
best 0.993 0.989 0.986 0.978 0.957 0.945
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyROR (NR1F) {2.1.2.6} (TFClass)
TFClass IDTFClass: 2.1.2.6.3
HGNCHGNC:10260
MGIMGI:104856
EntrezGene (human)GeneID:6097
(SSTAR profile)
EntrezGene (mouse)GeneID:19885
(SSTAR profile)
UniProt ID (human)RORG_HUMAN
UniProt ID (mouse)RORG_MOUSE
UniProt AC (human)P51449
(TFClass)
UniProt AC (mouse)P51450
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 7 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01311.0142.0397.0150.0
02492.078.0204.0226.0
03924.027.014.035.0
04716.08.015.0261.0
0596.0328.0449.0127.0
0612.054.073.0861.0
07650.05.0329.016.0
0843.02.0922.033.0
0910.020.0960.010.0
1047.074.0104.0775.0
119.0926.019.046.0
12945.07.032.016.0
PFM
ACGT
010.3110.1420.3970.15
020.4920.0780.2040.226
030.9240.0270.0140.035
040.7160.0080.0150.261
050.0960.3280.4490.127
060.0120.0540.0730.861
070.650.0050.3290.016
080.0430.0020.9220.033
090.010.020.960.01
100.0470.0740.1040.775
110.0090.9260.0190.046
120.9450.0070.0320.016
PWM
ACGT
010.217-0.560.46-0.506
020.674-1.15-0.202-0.1
031.302-2.171-2.773-1.925
041.048-3.253-2.7110.043
05-0.9460.270.583-0.671
06-2.909-1.508-1.2151.232
070.951-3.6220.273-2.653
08-1.728-4.2131.3-1.981
09-3.066-2.451.34-3.066
10-1.642-1.201-0.8671.127
11-3.1561.304-2.497-1.663
121.325-3.362-2.01-2.653
Standard thresholds
P-value Threshold
0.001 3.96051
0.0005 4.949515
0.0001 7.11018