| Motif | RORG.H12INVITRO.0.M.C |
| Gene (human) | RORC (GeneCards) |
| Gene synonyms (human) | NR1F3, RORG, RZRG |
| Gene (mouse) | Rorc |
| Gene synonyms (mouse) | Nr1f3, Rorg, Thor |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | C |
| Motif | RORG.H12INVITRO.0.M.C |
| Gene (human) | RORC (GeneCards) |
| Gene synonyms (human) | NR1F3, RORG, RZRG |
| Gene (mouse) | Rorc |
| Gene synonyms (mouse) | Nr1f3, Rorg, Thor |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | C |
| Motif length | 20 |
| Consensus | dnKRGGTMAbTAGGTCAnbd |
| GC content | 50.66% |
| Information content (bits; total / per base) | 19.555 / 0.978 |
| Data sources | Methyl-HT-SELEX |
| Aligned words | 4816 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mouse | 7 (44) | 0.726 | 0.882 | 0.645 | 0.829 | 0.705 | 0.869 | 2.463 | 3.571 | 34.727 | 151.824 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.996 | 0.995 | 0.98 | 0.974 | 0.928 | 0.916 |
| best | 0.999 | 0.999 | 0.984 | 0.981 | 0.931 | 0.916 | |
| Methyl HT-SELEX, 1 experiments | median | 0.999 | 0.999 | 0.984 | 0.981 | 0.924 | 0.916 |
| best | 0.999 | 0.999 | 0.984 | 0.981 | 0.924 | 0.916 | |
| Non-Methyl HT-SELEX, 1 experiments | median | 0.993 | 0.99 | 0.976 | 0.968 | 0.931 | 0.916 |
| best | 0.993 | 0.99 | 0.976 | 0.968 | 0.931 | 0.916 | |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | Nuclear receptors with C4 zinc fingers {2.1} (TFClass) |
| TF family | Thyroid hormone receptor-related {2.1.2} (TFClass) |
| TF subfamily | ROR (NR1F) {2.1.2.6} (TFClass) |
| TFClass ID | TFClass: 2.1.2.6.3 |
| HGNC | HGNC:10260 |
| MGI | MGI:104856 |
| EntrezGene (human) | GeneID:6097 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:19885 (SSTAR profile) |
| UniProt ID (human) | RORG_HUMAN |
| UniProt ID (mouse) | RORG_MOUSE |
| UniProt AC (human) | P51449 (TFClass) |
| UniProt AC (mouse) | P51450 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 7 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 1 |
| PCM | RORG.H12INVITRO.0.M.C.pcm |
| PWM | RORG.H12INVITRO.0.M.C.pwm |
| PFM | RORG.H12INVITRO.0.M.C.pfm |
| Alignment | RORG.H12INVITRO.0.M.C.words.tsv |
| Threshold to P-value map | RORG.H12INVITRO.0.M.C.thr |
| Motif in other formats | |
| JASPAR format | RORG.H12INVITRO.0.M.C_jaspar_format.txt |
| MEME format | RORG.H12INVITRO.0.M.C_meme_format.meme |
| Transfac format | RORG.H12INVITRO.0.M.C_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2045.5 | 416.5 | 774.5 | 1579.5 |
| 02 | 759.25 | 1116.25 | 1690.25 | 1250.25 |
| 03 | 393.0 | 647.0 | 886.0 | 2890.0 |
| 04 | 2674.0 | 147.0 | 1798.0 | 197.0 |
| 05 | 174.0 | 191.0 | 4165.0 | 286.0 |
| 06 | 169.0 | 127.0 | 4317.0 | 203.0 |
| 07 | 330.0 | 112.0 | 472.0 | 3902.0 |
| 08 | 1055.0 | 2859.0 | 13.0 | 889.0 |
| 09 | 4519.0 | 0.0 | 34.0 | 263.0 |
| 10 | 482.0 | 893.0 | 2865.0 | 576.0 |
| 11 | 34.0 | 124.0 | 219.0 | 4439.0 |
| 12 | 3833.0 | 1.0 | 981.0 | 1.0 |
| 13 | 0.0 | 0.0 | 4808.0 | 8.0 |
| 14 | 1.0 | 0.0 | 4815.0 | 0.0 |
| 15 | 10.0 | 18.0 | 156.0 | 4632.0 |
| 16 | 2.0 | 4732.0 | 6.0 | 76.0 |
| 17 | 3904.0 | 3.0 | 903.0 | 6.0 |
| 18 | 1110.0 | 1320.0 | 1317.0 | 1069.0 |
| 19 | 642.75 | 738.75 | 2346.75 | 1087.75 |
| 20 | 1002.25 | 766.25 | 2017.25 | 1030.25 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.425 | 0.086 | 0.161 | 0.328 |
| 02 | 0.158 | 0.232 | 0.351 | 0.26 |
| 03 | 0.082 | 0.134 | 0.184 | 0.6 |
| 04 | 0.555 | 0.031 | 0.373 | 0.041 |
| 05 | 0.036 | 0.04 | 0.865 | 0.059 |
| 06 | 0.035 | 0.026 | 0.896 | 0.042 |
| 07 | 0.069 | 0.023 | 0.098 | 0.81 |
| 08 | 0.219 | 0.594 | 0.003 | 0.185 |
| 09 | 0.938 | 0.0 | 0.007 | 0.055 |
| 10 | 0.1 | 0.185 | 0.595 | 0.12 |
| 11 | 0.007 | 0.026 | 0.045 | 0.922 |
| 12 | 0.796 | 0.0 | 0.204 | 0.0 |
| 13 | 0.0 | 0.0 | 0.998 | 0.002 |
| 14 | 0.0 | 0.0 | 1.0 | 0.0 |
| 15 | 0.002 | 0.004 | 0.032 | 0.962 |
| 16 | 0.0 | 0.983 | 0.001 | 0.016 |
| 17 | 0.811 | 0.001 | 0.188 | 0.001 |
| 18 | 0.23 | 0.274 | 0.273 | 0.222 |
| 19 | 0.133 | 0.153 | 0.487 | 0.226 |
| 20 | 0.208 | 0.159 | 0.419 | 0.214 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.529 | -1.058 | -0.44 | 0.271 |
| 02 | -0.46 | -0.076 | 0.339 | 0.038 |
| 03 | -1.116 | -0.62 | -0.306 | 0.875 |
| 04 | 0.797 | -2.09 | 0.4 | -1.801 |
| 05 | -1.924 | -1.832 | 1.24 | -1.432 |
| 06 | -1.953 | -2.234 | 1.276 | -1.772 |
| 07 | -1.29 | -2.358 | -0.934 | 1.175 |
| 08 | -0.132 | 0.864 | -4.379 | -0.303 |
| 09 | 1.321 | -6.344 | -3.508 | -1.515 |
| 10 | -0.913 | -0.298 | 0.866 | -0.735 |
| 11 | -3.508 | -2.258 | -1.696 | 1.303 |
| 12 | 1.157 | -5.957 | -0.204 | -5.957 |
| 13 | -6.344 | -6.344 | 1.383 | -4.781 |
| 14 | -5.957 | -6.344 | 1.385 | -6.344 |
| 15 | -4.6 | -4.093 | -2.032 | 1.346 |
| 16 | -5.679 | 1.367 | -5.001 | -2.737 |
| 17 | 1.175 | -5.462 | -0.287 | -5.001 |
| 18 | -0.081 | 0.092 | 0.09 | -0.119 |
| 19 | -0.626 | -0.487 | 0.667 | -0.101 |
| 20 | -0.183 | -0.451 | 0.515 | -0.156 |
| P-value | Threshold |
|---|---|
| 0.001 | -0.70364 |
| 0.0005 | 0.96556 |
| 0.0001 | 4.42491 |