MotifRORB.H12INVITRO.0.SM.B
Gene (human)RORB
(GeneCards)
Gene synonyms (human)NR1F2, RZRB
Gene (mouse)Rorb
Gene synonyms (mouse)Nr1f2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length17
ConsensusnvddMWnTAGGTCAnbn
GC content48.07%
Information content (bits; total / per base)13.74 / 0.808
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9995

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.998 0.997 0.994 0.991 0.971 0.964
best 0.999 0.998 0.995 0.993 0.971 0.965
Methyl HT-SELEX, 1 experiments median 0.998 0.997 0.992 0.99 0.971 0.964
best 0.998 0.997 0.992 0.99 0.971 0.964
Non-Methyl HT-SELEX, 1 experiments median 0.999 0.998 0.995 0.993 0.97 0.965
best 0.999 0.998 0.995 0.993 0.97 0.965
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyROR (NR1F) {2.1.2.6} (TFClass)
TFClass IDTFClass: 2.1.2.6.2
HGNCHGNC:10259
MGIMGI:1343464
EntrezGene (human)
EntrezGene (mouse)GeneID:225998
(SSTAR profile)
UniProt ID (human)RORB_HUMAN
UniProt ID (mouse)RORB_MOUSE
UniProt AC (human)Q92753
(TFClass)
UniProt AC (mouse)Q8R1B8
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
013329.752232.752661.751770.75
021750.752266.754293.751683.75
031900.01756.04355.01984.0
042285.01078.01964.04668.0
056044.02098.0479.01374.0
066162.0409.0577.02847.0
071359.03063.03315.02258.0
08235.0462.01331.07967.0
098260.012.01720.03.0
100.01.09988.06.0
110.01.09993.01.0
124.051.071.09869.0
130.09896.02.097.0
149527.05.0457.06.0
152057.02949.02145.02844.0
161205.751962.754819.752006.75
172516.252116.253144.252218.25
PFM
ACGT
010.3330.2230.2660.177
020.1750.2270.430.168
030.190.1760.4360.198
040.2290.1080.1960.467
050.6050.210.0480.137
060.6170.0410.0580.285
070.1360.3060.3320.226
080.0240.0460.1330.797
090.8260.0010.1720.0
100.00.00.9990.001
110.00.01.00.0
120.00.0050.0070.987
130.00.990.00.01
140.9530.0010.0460.001
150.2060.2950.2150.285
160.1210.1960.4820.201
170.2520.2120.3150.222
PWM
ACGT
010.287-0.1120.063-0.344
02-0.355-0.0970.541-0.394
03-0.274-0.3520.555-0.23
04-0.089-0.839-0.2410.625
050.883-0.175-1.648-0.597
060.902-1.805-1.4630.13
07-0.6080.2030.282-0.101
08-2.355-1.684-0.6291.159
091.195-5.164-0.373-6.156
10-6.99-6.631.385-5.708
11-6.99-6.631.385-6.63
12-5.984-3.848-3.531.373
13-6.991.376-6.365-3.226
141.338-5.836-1.695-5.708
15-0.1940.166-0.1520.129
16-0.728-0.2410.656-0.219
170.007-0.1660.23-0.119
Standard thresholds
P-value Threshold
0.001 2.36621
0.0005 3.96326
0.0001 7.04411