RORB.H12INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	RORB.H12INVITRO.0.SM.B
Gene (human)	RORB (GeneCards)
Gene synonyms (human)	NR1F2, RZRB
Gene (mouse)	Rorb
Gene synonyms (mouse)	Nr1f2
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	17
Consensus	nvddMWnTAGGTCAnbn
GC content	48.07%
Information content (bits; total / per base)	13.74 / 0.808
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9995

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.998	0.997	0.994	0.991	0.971	0.964
Overall, 2 experiments	best	0.999	0.998	0.995	0.993	0.971	0.965
Methyl HT-SELEX, 1 experiments	median	0.998	0.997	0.992	0.99	0.971	0.964
Methyl HT-SELEX, 1 experiments	best	0.998	0.997	0.992	0.99	0.971	0.964
Non-Methyl HT-SELEX, 1 experiments	median	0.999	0.998	0.995	0.993	0.97	0.965
Non-Methyl HT-SELEX, 1 experiments	best	0.999	0.998	0.995	0.993	0.97	0.965

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	Thyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamily	ROR (NR1F) {2.1.2.6} (TFClass)
TFClass ID	TFClass: 2.1.2.6.2
HGNC	HGNC:10259
MGI	MGI:1343464
EntrezGene (human)
EntrezGene (mouse)	GeneID:225998 (SSTAR profile)
UniProt ID (human)	RORB_HUMAN
UniProt ID (mouse)	RORB_MOUSE
UniProt AC (human)	Q92753 (TFClass)
UniProt AC (mouse)	Q8R1B8 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	RORB.H12INVITRO.0.SM.B.pcm
PWM	RORB.H12INVITRO.0.SM.B.pwm
PFM	RORB.H12INVITRO.0.SM.B.pfm
Alignment	RORB.H12INVITRO.0.SM.B.words.tsv
Threshold to P-value map	RORB.H12INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	RORB.H12INVITRO.0.SM.B_jaspar_format.txt
MEME format	RORB.H12INVITRO.0.SM.B_meme_format.meme
Transfac format	RORB.H12INVITRO.0.SM.B_transfac_format.txt
Homer format	RORB.H12INVITRO.0.SM.B_homer_format_0.001.txt RORB.H12INVITRO.0.SM.B_homer_format_0.0005.txt RORB.H12INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	3329.75	2232.75	2661.75	1770.75
02	1750.75	2266.75	4293.75	1683.75
03	1900.0	1756.0	4355.0	1984.0
04	2285.0	1078.0	1964.0	4668.0
05	6044.0	2098.0	479.0	1374.0
06	6162.0	409.0	577.0	2847.0
07	1359.0	3063.0	3315.0	2258.0
08	235.0	462.0	1331.0	7967.0
09	8260.0	12.0	1720.0	3.0
10	0.0	1.0	9988.0	6.0
11	0.0	1.0	9993.0	1.0
12	4.0	51.0	71.0	9869.0
13	0.0	9896.0	2.0	97.0
14	9527.0	5.0	457.0	6.0
15	2057.0	2949.0	2145.0	2844.0
16	1205.75	1962.75	4819.75	2006.75
17	2516.25	2116.25	3144.25	2218.25

PFM

	A	C	G	T
01	0.333	0.223	0.266	0.177
02	0.175	0.227	0.43	0.168
03	0.19	0.176	0.436	0.198
04	0.229	0.108	0.196	0.467
05	0.605	0.21	0.048	0.137
06	0.617	0.041	0.058	0.285
07	0.136	0.306	0.332	0.226
08	0.024	0.046	0.133	0.797
09	0.826	0.001	0.172	0.0
10	0.0	0.0	0.999	0.001
11	0.0	0.0	1.0	0.0
12	0.0	0.005	0.007	0.987
13	0.0	0.99	0.0	0.01
14	0.953	0.001	0.046	0.001
15	0.206	0.295	0.215	0.285
16	0.121	0.196	0.482	0.201
17	0.252	0.212	0.315	0.222

PWM

	A	C	G	T
01	0.287	-0.112	0.063	-0.344
02	-0.355	-0.097	0.541	-0.394
03	-0.274	-0.352	0.555	-0.23
04	-0.089	-0.839	-0.241	0.625
05	0.883	-0.175	-1.648	-0.597
06	0.902	-1.805	-1.463	0.13
07	-0.608	0.203	0.282	-0.101
08	-2.355	-1.684	-0.629	1.159
09	1.195	-5.164	-0.373	-6.156
10	-6.99	-6.63	1.385	-5.708
11	-6.99	-6.63	1.385	-6.63
12	-5.984	-3.848	-3.53	1.373
13	-6.99	1.376	-6.365	-3.226
14	1.338	-5.836	-1.695	-5.708
15	-0.194	0.166	-0.152	0.129
16	-0.728	-0.241	0.656	-0.219
17	0.007	-0.166	0.23	-0.119

Standard thresholds

P-value	Threshold
0.001	2.36621
0.0005	3.96326
0.0001	7.04411