RFX7.H12INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	RFX7.H12INVITRO.0.SM.B
Gene (human)	RFX7 (GeneCards)
Gene synonyms (human)	RFXDC2
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	12
Consensus	nbGTYRYbdnvn
GC content	55.27%
Information content (bits; total / per base)	7.291 / 0.608
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	5807

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.951	0.927	0.899	0.866	0.819	0.791
Overall, 2 experiments	best	0.954	0.933	0.9	0.868	0.828	0.796
Methyl HT-SELEX, 1 experiments	median	0.954	0.933	0.898	0.868	0.81	0.786
Methyl HT-SELEX, 1 experiments	best	0.954	0.933	0.898	0.868	0.81	0.786
Non-Methyl HT-SELEX, 1 experiments	median	0.947	0.92	0.9	0.864	0.828	0.796
Non-Methyl HT-SELEX, 1 experiments	best	0.947	0.92	0.9	0.864	0.828	0.796

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	RFX {3.3.3} (TFClass)
TF subfamily	{3.3.3.0} (TFClass)
TFClass ID	TFClass: 3.3.3.0.7
HGNC	HGNC:25777
MGI
EntrezGene (human)	GeneID:64864 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	RFX7_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q2KHR2 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	RFX7.H12INVITRO.0.SM.B.pcm
PWM	RFX7.H12INVITRO.0.SM.B.pwm
PFM	RFX7.H12INVITRO.0.SM.B.pfm
Alignment	RFX7.H12INVITRO.0.SM.B.words.tsv
Threshold to P-value map	RFX7.H12INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	RFX7.H12INVITRO.0.SM.B_jaspar_format.txt
MEME format	RFX7.H12INVITRO.0.SM.B_meme_format.meme
Transfac format	RFX7.H12INVITRO.0.SM.B_transfac_format.txt
Homer format	RFX7.H12INVITRO.0.SM.B_homer_format_0.001.txt RFX7.H12INVITRO.0.SM.B_homer_format_0.0005.txt RFX7.H12INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1334.25	1462.25	1758.25	1252.25
02	459.75	3004.75	1100.75	1241.75
03	95.0	1.0	5710.0	1.0
04	119.0	0.0	0.0	5688.0
05	735.0	818.0	33.0	4221.0
06	1622.0	69.0	3794.0	322.0
07	281.0	3990.0	558.0	978.0
08	380.0	2022.0	1288.0	2117.0
09	2809.0	476.0	1700.0	822.0
10	921.0	1580.0	1146.0	2160.0
11	827.0	1114.0	3358.0	508.0
12	931.75	1851.75	1681.75	1341.75

PFM

	A	C	G	T
01	0.23	0.252	0.303	0.216
02	0.079	0.517	0.19	0.214
03	0.016	0.0	0.983	0.0
04	0.02	0.0	0.0	0.98
05	0.127	0.141	0.006	0.727
06	0.279	0.012	0.653	0.055
07	0.048	0.687	0.096	0.168
08	0.065	0.348	0.222	0.365
09	0.484	0.082	0.293	0.142
10	0.159	0.272	0.197	0.372
11	0.142	0.192	0.578	0.087
12	0.16	0.319	0.29	0.231

PWM

	A	C	G	T
01	-0.084	0.007	0.191	-0.148
02	-1.147	0.727	-0.276	-0.156
03	-2.706	-6.129	1.368	-6.129
04	-2.485	-6.509	-6.509	1.364
05	-0.679	-0.573	-3.722	1.066
06	0.111	-3.017	0.96	-1.501
07	-1.636	1.01	-0.954	-0.394
08	-1.336	0.331	-0.119	0.377
09	0.659	-1.112	0.158	-0.568
10	-0.454	0.085	-0.236	0.397
11	-0.562	-0.264	0.838	-1.047
12	-0.443	0.243	0.147	-0.079

Standard thresholds

P-value	Threshold
0.001	5.199365
0.0005	5.77786
0.0001	6.883545