| Motif | RFX5.H12RSNP.0.P.B |
| Gene (human) | RFX5 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Rfx5 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | RFX5.H12RSNP.0.P.B |
| Gene (human) | RFX5 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Rfx5 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 19 |
| Consensus | bMvnYdGTYRCYRKGbvvv |
| GC content | 54.1% |
| Information content (bits; total / per base) | 12.391 / 0.652 |
| Data sources | ChIP-Seq |
| Aligned words | 1000 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 6 (41) | 0.871 | 0.954 | 0.829 | 0.924 | 0.861 | 0.94 | 4.201 | 5.386 | 282.469 | 530.377 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.984 | 0.974 | 0.926 | 0.917 | 0.818 | 0.825 |
| best | 0.993 | 0.988 | 0.988 | 0.98 | 0.974 | 0.963 | |
| Methyl HT-SELEX, 1 experiments | median | 0.984 | 0.973 | 0.971 | 0.956 | 0.937 | 0.916 |
| best | 0.984 | 0.973 | 0.971 | 0.956 | 0.937 | 0.916 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.984 | 0.975 | 0.881 | 0.878 | 0.7 | 0.734 |
| best | 0.993 | 0.988 | 0.988 | 0.98 | 0.974 | 0.963 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 2.909 | 1.58 | 0.122 | -0.002 |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.668 | 0.257 | 0.634 | 0.431 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Fork head/winged helix factors {3.3} (TFClass) |
| TF family | RFX {3.3.3} (TFClass) |
| TF subfamily | {3.3.3.0} (TFClass) |
| TFClass ID | TFClass: 3.3.3.0.5 |
| HGNC | HGNC:9986 |
| MGI | MGI:1858421 |
| EntrezGene (human) | GeneID:5993 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:53970 (SSTAR profile) |
| UniProt ID (human) | RFX5_HUMAN |
| UniProt ID (mouse) | RFX5_MOUSE |
| UniProt AC (human) | P48382 (TFClass) |
| UniProt AC (mouse) | Q9JL61 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 6 human, 0 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | RFX5.H12RSNP.0.P.B.pcm |
| PWM | RFX5.H12RSNP.0.P.B.pwm |
| PFM | RFX5.H12RSNP.0.P.B.pfm |
| Alignment | RFX5.H12RSNP.0.P.B.words.tsv |
| Threshold to P-value map | RFX5.H12RSNP.0.P.B.thr |
| Motif in other formats | |
| JASPAR format | RFX5.H12RSNP.0.P.B_jaspar_format.txt |
| MEME format | RFX5.H12RSNP.0.P.B_meme_format.meme |
| Transfac format | RFX5.H12RSNP.0.P.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 81.0 | 165.0 | 184.0 | 570.0 |
| 02 | 149.0 | 608.0 | 134.0 | 109.0 |
| 03 | 562.0 | 185.0 | 154.0 | 99.0 |
| 04 | 94.0 | 288.0 | 330.0 | 288.0 |
| 05 | 55.0 | 606.0 | 106.0 | 233.0 |
| 06 | 249.0 | 67.0 | 200.0 | 484.0 |
| 07 | 24.0 | 13.0 | 957.0 | 6.0 |
| 08 | 9.0 | 46.0 | 25.0 | 920.0 |
| 09 | 71.0 | 146.0 | 18.0 | 765.0 |
| 10 | 170.0 | 25.0 | 660.0 | 145.0 |
| 11 | 19.0 | 912.0 | 15.0 | 54.0 |
| 12 | 10.0 | 466.0 | 16.0 | 508.0 |
| 13 | 691.0 | 15.0 | 254.0 | 40.0 |
| 14 | 151.0 | 40.0 | 590.0 | 219.0 |
| 15 | 53.0 | 57.0 | 855.0 | 35.0 |
| 16 | 118.0 | 375.0 | 347.0 | 160.0 |
| 17 | 478.0 | 190.0 | 226.0 | 106.0 |
| 18 | 336.0 | 118.0 | 477.0 | 69.0 |
| 19 | 465.0 | 174.0 | 235.0 | 126.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.081 | 0.165 | 0.184 | 0.57 |
| 02 | 0.149 | 0.608 | 0.134 | 0.109 |
| 03 | 0.562 | 0.185 | 0.154 | 0.099 |
| 04 | 0.094 | 0.288 | 0.33 | 0.288 |
| 05 | 0.055 | 0.606 | 0.106 | 0.233 |
| 06 | 0.249 | 0.067 | 0.2 | 0.484 |
| 07 | 0.024 | 0.013 | 0.957 | 0.006 |
| 08 | 0.009 | 0.046 | 0.025 | 0.92 |
| 09 | 0.071 | 0.146 | 0.018 | 0.765 |
| 10 | 0.17 | 0.025 | 0.66 | 0.145 |
| 11 | 0.019 | 0.912 | 0.015 | 0.054 |
| 12 | 0.01 | 0.466 | 0.016 | 0.508 |
| 13 | 0.691 | 0.015 | 0.254 | 0.04 |
| 14 | 0.151 | 0.04 | 0.59 | 0.219 |
| 15 | 0.053 | 0.057 | 0.855 | 0.035 |
| 16 | 0.118 | 0.375 | 0.347 | 0.16 |
| 17 | 0.478 | 0.19 | 0.226 | 0.106 |
| 18 | 0.336 | 0.118 | 0.477 | 0.069 |
| 19 | 0.465 | 0.174 | 0.235 | 0.126 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -1.113 | -0.412 | -0.304 | 0.82 |
| 02 | -0.513 | 0.885 | -0.618 | -0.821 |
| 03 | 0.806 | -0.299 | -0.48 | -0.916 |
| 04 | -0.967 | 0.141 | 0.276 | 0.141 |
| 05 | -1.49 | 0.881 | -0.849 | -0.07 |
| 06 | -0.004 | -1.298 | -0.221 | 0.657 |
| 07 | -2.281 | -2.839 | 1.337 | -3.484 |
| 08 | -3.156 | -1.663 | -2.243 | 1.298 |
| 09 | -1.242 | -0.533 | -2.546 | 1.114 |
| 10 | -0.382 | -2.243 | 0.967 | -0.54 |
| 11 | -2.497 | 1.289 | -2.711 | -1.508 |
| 12 | -3.066 | 0.62 | -2.653 | 0.706 |
| 13 | 1.012 | -2.711 | 0.016 | -1.797 |
| 14 | -0.5 | -1.797 | 0.855 | -0.131 |
| 15 | -1.526 | -1.455 | 1.225 | -1.925 |
| 16 | -0.743 | 0.403 | 0.326 | -0.442 |
| 17 | 0.645 | -0.272 | -0.1 | -0.849 |
| 18 | 0.294 | -0.743 | 0.643 | -1.27 |
| 19 | 0.617 | -0.359 | -0.061 | -0.678 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.13906 |
| 0.0005 | 5.07866 |
| 0.0001 | 7.04121 |