MotifRFX5.H12INVIVO.2.S.B
Gene (human)RFX5
(GeneCards)
Gene synonyms (human)
Gene (mouse)Rfx5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length18
ConsensusnbSGTTGCCATGGYAACv
GC content54.59%
Information content (bits; total / per base)22.292 / 1.238
Data sourcesHT-SELEX
Aligned words9183

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 6 (41) 0.745 0.785 0.656 0.699 0.661 0.705 2.223 2.645 78.585 119.959

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.999 0.999 0.956 0.958 0.852 0.865
best 1.0 1.0 0.998 0.998 0.991 0.988
Methyl HT-SELEX, 1 experiments median 0.999 0.999 0.992 0.989 0.965 0.957
best 0.999 0.999 0.992 0.989 0.965 0.957
Non-Methyl HT-SELEX, 3 experiments median 1.0 1.0 0.921 0.927 0.739 0.773
best 1.0 1.0 0.998 0.998 0.991 0.988

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 1.596 0.492 0.1 0.022

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.643 0.349 0.673 0.449
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyRFX {3.3.3} (TFClass)
TF subfamily {3.3.3.0} (TFClass)
TFClass IDTFClass: 3.3.3.0.5
HGNCHGNC:9986
MGIMGI:1858421
EntrezGene (human)GeneID:5993
(SSTAR profile)
EntrezGene (mouse)GeneID:53970
(SSTAR profile)
UniProt ID (human)RFX5_HUMAN
UniProt ID (mouse)RFX5_MOUSE
UniProt AC (human)P48382
(TFClass)
UniProt AC (mouse)Q9JL61
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 6 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012458.02713.01922.02090.0
021142.754235.751989.751814.75
03470.04711.03163.0839.0
0412.00.09157.014.0
058.08.02.09165.0
064.05.01.09173.0
07443.03.08727.010.0
081.09164.00.018.0
093.05814.011.03355.0
109040.04.018.0121.0
11186.052.0108.08837.0
12540.054.08564.025.0
13135.0355.08512.0181.0
14540.04413.0633.03597.0
157993.0224.0396.0570.0
168099.0226.0329.0529.0
17370.257841.25426.25545.25
181671.02924.03523.01065.0
PFM
ACGT
010.2680.2950.2090.228
020.1240.4610.2170.198
030.0510.5130.3440.091
040.0010.00.9970.002
050.0010.0010.00.998
060.00.0010.00.999
070.0480.00.950.001
080.00.9980.00.002
090.00.6330.0010.365
100.9840.00.0020.013
110.020.0060.0120.962
120.0590.0060.9330.003
130.0150.0390.9270.02
140.0590.4810.0690.392
150.870.0240.0430.062
160.8820.0250.0360.058
170.040.8540.0460.059
180.1820.3180.3840.116
PWM
ACGT
010.0680.167-0.178-0.094
02-0.6970.612-0.143-0.235
03-1.5820.7180.32-1.005
04-5.081-6.9151.383-4.95
05-5.409-5.409-6.2861.384
06-5.902-5.755-6.5521.384
07-1.641-6.0761.335-5.232
08-6.5521.383-6.915-4.73
09-6.0760.929-5.1530.379
101.37-5.902-4.73-2.925
11-2.502-3.746-3.0371.347
12-1.444-3.7091.316-4.434
13-2.818-1.8611.31-2.529
14-1.4440.653-1.2860.449
151.247-2.318-1.753-1.39
161.26-2.309-1.937-1.465
17-1.8191.228-1.679-1.434
18-0.3170.2420.428-0.767
Standard thresholds
P-value Threshold
0.001 -3.84169
0.0005 -1.92384
0.0001 2.10751