| Motif | RFX5.H12CORE.0.P.B |
| Gene (human) | RFX5 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Rfx5 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | RFX5.H12CORE.0.P.B |
| Gene (human) | RFX5 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Rfx5 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 20 |
| Consensus | vbSRbbdGTYRCYRKGvvvv |
| GC content | 53.36% |
| Information content (bits; total / per base) | 13.313 / 0.666 |
| Data sources | ChIP-Seq |
| Aligned words | 460 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 6 (41) | 0.881 | 0.97 | 0.843 | 0.952 | 0.87 | 0.959 | 4.402 | 5.617 | 300.201 | 557.222 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.986 | 0.978 | 0.926 | 0.919 | 0.821 | 0.83 |
| best | 0.994 | 0.99 | 0.99 | 0.984 | 0.977 | 0.968 | |
| Methyl HT-SELEX, 1 experiments | median | 0.988 | 0.98 | 0.978 | 0.965 | 0.947 | 0.93 |
| best | 0.988 | 0.98 | 0.978 | 0.965 | 0.947 | 0.93 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.985 | 0.977 | 0.874 | 0.873 | 0.694 | 0.73 |
| best | 0.994 | 0.99 | 0.99 | 0.984 | 0.977 | 0.968 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 1.196 | 0.155 | 0.096 | -0.009 |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.688 | 0.296 | 0.622 | 0.414 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Fork head/winged helix factors {3.3} (TFClass) |
| TF family | RFX {3.3.3} (TFClass) |
| TF subfamily | {3.3.3.0} (TFClass) |
| TFClass ID | TFClass: 3.3.3.0.5 |
| HGNC | HGNC:9986 |
| MGI | MGI:1858421 |
| EntrezGene (human) | GeneID:5993 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:53970 (SSTAR profile) |
| UniProt ID (human) | RFX5_HUMAN |
| UniProt ID (mouse) | RFX5_MOUSE |
| UniProt AC (human) | P48382 (TFClass) |
| UniProt AC (mouse) | Q9JL61 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 6 human, 0 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | RFX5.H12CORE.0.P.B.pcm |
| PWM | RFX5.H12CORE.0.P.B.pwm |
| PFM | RFX5.H12CORE.0.P.B.pfm |
| Alignment | RFX5.H12CORE.0.P.B.words.tsv |
| Threshold to P-value map | RFX5.H12CORE.0.P.B.thr |
| Motif in other formats | |
| JASPAR format | RFX5.H12CORE.0.P.B_jaspar_format.txt |
| MEME format | RFX5.H12CORE.0.P.B_meme_format.meme |
| Transfac format | RFX5.H12CORE.0.P.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 100.0 | 86.0 | 228.0 | 46.0 |
| 02 | 53.0 | 68.0 | 65.0 | 274.0 |
| 03 | 59.0 | 286.0 | 60.0 | 55.0 |
| 04 | 276.0 | 60.0 | 81.0 | 43.0 |
| 05 | 50.0 | 135.0 | 123.0 | 152.0 |
| 06 | 25.0 | 250.0 | 60.0 | 125.0 |
| 07 | 128.0 | 29.0 | 89.0 | 214.0 |
| 08 | 19.0 | 5.0 | 433.0 | 3.0 |
| 09 | 4.0 | 9.0 | 9.0 | 438.0 |
| 10 | 26.0 | 86.0 | 5.0 | 343.0 |
| 11 | 77.0 | 7.0 | 315.0 | 61.0 |
| 12 | 3.0 | 418.0 | 7.0 | 32.0 |
| 13 | 5.0 | 202.0 | 5.0 | 248.0 |
| 14 | 339.0 | 5.0 | 103.0 | 13.0 |
| 15 | 66.0 | 6.0 | 295.0 | 93.0 |
| 16 | 19.0 | 29.0 | 402.0 | 10.0 |
| 17 | 59.0 | 157.0 | 187.0 | 57.0 |
| 18 | 221.0 | 84.0 | 124.0 | 31.0 |
| 19 | 170.0 | 57.0 | 188.0 | 45.0 |
| 20 | 244.0 | 77.0 | 74.0 | 65.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.217 | 0.187 | 0.496 | 0.1 |
| 02 | 0.115 | 0.148 | 0.141 | 0.596 |
| 03 | 0.128 | 0.622 | 0.13 | 0.12 |
| 04 | 0.6 | 0.13 | 0.176 | 0.093 |
| 05 | 0.109 | 0.293 | 0.267 | 0.33 |
| 06 | 0.054 | 0.543 | 0.13 | 0.272 |
| 07 | 0.278 | 0.063 | 0.193 | 0.465 |
| 08 | 0.041 | 0.011 | 0.941 | 0.007 |
| 09 | 0.009 | 0.02 | 0.02 | 0.952 |
| 10 | 0.057 | 0.187 | 0.011 | 0.746 |
| 11 | 0.167 | 0.015 | 0.685 | 0.133 |
| 12 | 0.007 | 0.909 | 0.015 | 0.07 |
| 13 | 0.011 | 0.439 | 0.011 | 0.539 |
| 14 | 0.737 | 0.011 | 0.224 | 0.028 |
| 15 | 0.143 | 0.013 | 0.641 | 0.202 |
| 16 | 0.041 | 0.063 | 0.874 | 0.022 |
| 17 | 0.128 | 0.341 | 0.407 | 0.124 |
| 18 | 0.48 | 0.183 | 0.27 | 0.067 |
| 19 | 0.37 | 0.124 | 0.409 | 0.098 |
| 20 | 0.53 | 0.167 | 0.161 | 0.141 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.138 | -0.286 | 0.678 | -0.897 |
| 02 | -0.759 | -0.516 | -0.56 | 0.861 |
| 03 | -0.655 | 0.903 | -0.639 | -0.723 |
| 04 | 0.868 | -0.639 | -0.345 | -0.962 |
| 05 | -0.816 | 0.158 | 0.066 | 0.276 |
| 06 | -1.48 | 0.769 | -0.639 | 0.082 |
| 07 | 0.106 | -1.339 | -0.252 | 0.615 |
| 08 | -1.736 | -2.881 | 1.316 | -3.247 |
| 09 | -3.047 | -2.404 | -2.404 | 1.328 |
| 10 | -1.443 | -0.286 | -2.881 | 1.084 |
| 11 | -0.395 | -2.614 | 0.999 | -0.622 |
| 12 | -3.247 | 1.281 | -2.614 | -1.246 |
| 13 | -2.881 | 0.558 | -2.881 | 0.761 |
| 14 | 1.072 | -2.881 | -0.109 | -2.082 |
| 15 | -0.546 | -2.739 | 0.934 | -0.209 |
| 16 | -1.736 | -1.339 | 1.242 | -2.313 |
| 17 | -0.655 | 0.308 | 0.481 | -0.689 |
| 18 | 0.647 | -0.309 | 0.074 | -1.276 |
| 19 | 0.387 | -0.689 | 0.486 | -0.918 |
| 20 | 0.745 | -0.395 | -0.434 | -0.56 |
| P-value | Threshold |
|---|---|
| 0.001 | 3.92266 |
| 0.0005 | 4.90406 |
| 0.0001 | 6.95586 |