| Motif | RFX3.H12RSNP.2.S.B |
| Gene (human) | RFX3 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Rfx3 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 2 |
| Quality | B |
| Motif | RFX3.H12RSNP.2.S.B |
| Gene (human) | RFX3 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Rfx3 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 2 |
| Quality | B |
| Motif length | 20 |
| Consensus | ddKKKGTAGGKKAGGRdddd |
| GC content | 51.16% |
| Information content (bits; total / per base) | 16.799 / 0.84 |
| Data sources | HT-SELEX |
| Aligned words | 848 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 1 (7) | 0.419 | 0.446 | 0.29 | 0.305 | 0.558 | 0.579 | 1.269 | 1.322 | 0 | 0 |
| Mouse | 1 (5) | 0.446 | 0.446 | 0.303 | 0.304 | 0.588 | 0.593 | 1.386 | 1.405 | 0 | 0 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.527 | 0.517 | 0.517 | 0.509 | 0.511 | 0.505 |
| best | 0.755 | 0.752 | 0.624 | 0.637 | 0.553 | 0.577 | |
| Methyl HT-SELEX, 1 experiments | median | 0.534 | 0.52 | 0.516 | 0.512 | 0.496 | 0.504 |
| best | 0.534 | 0.52 | 0.516 | 0.512 | 0.496 | 0.504 | |
| Non-Methyl HT-SELEX, 5 experiments | median | 0.519 | 0.515 | 0.517 | 0.506 | 0.511 | 0.505 |
| best | 0.755 | 0.752 | 0.624 | 0.637 | 0.553 | 0.577 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.449 | 0.02 | -0.331 | -0.232 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Fork head/winged helix factors {3.3} (TFClass) |
| TF family | RFX {3.3.3} (TFClass) |
| TF subfamily | {3.3.3.0} (TFClass) |
| TFClass ID | TFClass: 3.3.3.0.3 |
| HGNC | HGNC:9984 |
| MGI | MGI:106582 |
| EntrezGene (human) | GeneID:5991 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:19726 (SSTAR profile) |
| UniProt ID (human) | RFX3_HUMAN |
| UniProt ID (mouse) | RFX3_MOUSE |
| UniProt AC (human) | P48380 (TFClass) |
| UniProt AC (mouse) | P48381 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 1 human, 1 mouse |
| HT-SELEX | 5 |
| Methyl-HT-SELEX | 1 |
| PCM | RFX3.H12RSNP.2.S.B.pcm |
| PWM | RFX3.H12RSNP.2.S.B.pwm |
| PFM | RFX3.H12RSNP.2.S.B.pfm |
| Alignment | RFX3.H12RSNP.2.S.B.words.tsv |
| Threshold to P-value map | RFX3.H12RSNP.2.S.B.thr |
| Motif in other formats | |
| JASPAR format | RFX3.H12RSNP.2.S.B_jaspar_format.txt |
| MEME format | RFX3.H12RSNP.2.S.B_meme_format.meme |
| Transfac format | RFX3.H12RSNP.2.S.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 174.75 | 123.75 | 342.75 | 206.75 |
| 02 | 237.5 | 90.5 | 324.5 | 195.5 |
| 03 | 61.0 | 33.0 | 634.0 | 120.0 |
| 04 | 53.0 | 34.0 | 154.0 | 607.0 |
| 05 | 31.0 | 43.0 | 159.0 | 615.0 |
| 06 | 50.0 | 10.0 | 758.0 | 30.0 |
| 07 | 6.0 | 34.0 | 73.0 | 735.0 |
| 08 | 746.0 | 3.0 | 11.0 | 88.0 |
| 09 | 2.0 | 0.0 | 772.0 | 74.0 |
| 10 | 0.0 | 0.0 | 767.0 | 81.0 |
| 11 | 25.0 | 6.0 | 241.0 | 576.0 |
| 12 | 36.0 | 18.0 | 159.0 | 635.0 |
| 13 | 715.0 | 7.0 | 67.0 | 59.0 |
| 14 | 52.0 | 4.0 | 696.0 | 96.0 |
| 15 | 89.0 | 11.0 | 715.0 | 33.0 |
| 16 | 90.0 | 51.0 | 623.0 | 84.0 |
| 17 | 312.0 | 66.0 | 378.0 | 92.0 |
| 18 | 152.0 | 55.0 | 385.0 | 256.0 |
| 19 | 128.0 | 78.0 | 382.0 | 260.0 |
| 20 | 148.0 | 101.0 | 268.0 | 331.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.206 | 0.146 | 0.404 | 0.244 |
| 02 | 0.28 | 0.107 | 0.383 | 0.231 |
| 03 | 0.072 | 0.039 | 0.748 | 0.142 |
| 04 | 0.063 | 0.04 | 0.182 | 0.716 |
| 05 | 0.037 | 0.051 | 0.188 | 0.725 |
| 06 | 0.059 | 0.012 | 0.894 | 0.035 |
| 07 | 0.007 | 0.04 | 0.086 | 0.867 |
| 08 | 0.88 | 0.004 | 0.013 | 0.104 |
| 09 | 0.002 | 0.0 | 0.91 | 0.087 |
| 10 | 0.0 | 0.0 | 0.904 | 0.096 |
| 11 | 0.029 | 0.007 | 0.284 | 0.679 |
| 12 | 0.042 | 0.021 | 0.188 | 0.749 |
| 13 | 0.843 | 0.008 | 0.079 | 0.07 |
| 14 | 0.061 | 0.005 | 0.821 | 0.113 |
| 15 | 0.105 | 0.013 | 0.843 | 0.039 |
| 16 | 0.106 | 0.06 | 0.735 | 0.099 |
| 17 | 0.368 | 0.078 | 0.446 | 0.108 |
| 18 | 0.179 | 0.065 | 0.454 | 0.302 |
| 19 | 0.151 | 0.092 | 0.45 | 0.307 |
| 20 | 0.175 | 0.119 | 0.316 | 0.39 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.192 | -0.533 | 0.477 | -0.025 |
| 02 | 0.113 | -0.841 | 0.423 | -0.08 |
| 03 | -1.226 | -1.818 | 1.09 | -0.563 |
| 04 | -1.363 | -1.79 | -0.317 | 1.047 |
| 05 | -1.878 | -1.565 | -0.285 | 1.06 |
| 06 | -1.419 | -2.906 | 1.268 | -1.909 |
| 07 | -3.325 | -1.79 | -1.051 | 1.238 |
| 08 | 1.252 | -3.82 | -2.824 | -0.868 |
| 09 | -4.06 | -4.842 | 1.287 | -1.038 |
| 10 | -4.842 | -4.842 | 1.28 | -0.949 |
| 11 | -2.08 | -3.325 | 0.127 | 0.995 |
| 12 | -1.735 | -2.385 | -0.285 | 1.092 |
| 13 | 1.21 | -3.203 | -1.135 | -1.259 |
| 14 | -1.381 | -3.627 | 1.183 | -0.783 |
| 15 | -0.857 | -2.824 | 1.21 | -1.818 |
| 16 | -0.846 | -1.4 | 1.073 | -0.914 |
| 17 | 0.384 | -1.15 | 0.575 | -0.825 |
| 18 | -0.33 | -1.327 | 0.593 | 0.187 |
| 19 | -0.499 | -0.986 | 0.585 | 0.203 |
| 20 | -0.356 | -0.733 | 0.233 | 0.443 |
| P-value | Threshold |
|---|---|
| 0.001 | 2.56811 |
| 0.0005 | 3.73586 |
| 0.0001 | 6.18921 |