MotifRFX3.H12INVITRO.1.PS.A
Gene (human)RFX3
(GeneCards)
Gene synonyms (human)
Gene (mouse)Rfx3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length14
ConsensusnbGTTRCCATGGnd
GC content52.3%
Information content (bits; total / per base)14.624 / 1.045
Data sourcesChIP-Seq + HT-SELEX
Aligned words9946

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.959 0.964 0.925 0.93 0.95 0.955 5.129 5.222 704.638 714.886
Mouse 1 (5) 0.963 0.963 0.933 0.934 0.955 0.956 5.314 5.352 727.745 816.796

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.737 0.751 0.607 0.628 0.548 0.572
best 1.0 1.0 1.0 0.999 0.935 0.942
Methyl HT-SELEX, 1 experiments median 1.0 1.0 1.0 0.999 0.935 0.942
best 1.0 1.0 1.0 0.999 0.935 0.942
Non-Methyl HT-SELEX, 5 experiments median 0.66 0.679 0.571 0.586 0.531 0.548
best 1.0 1.0 0.999 0.999 0.899 0.913

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.754 0.444 0.752 0.565
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyRFX {3.3.3} (TFClass)
TF subfamily {3.3.3.0} (TFClass)
TFClass IDTFClass: 3.3.3.0.3
HGNCHGNC:9984
MGIMGI:106582
EntrezGene (human)GeneID:5991
(SSTAR profile)
EntrezGene (mouse)GeneID:19726
(SSTAR profile)
UniProt ID (human)RFX3_HUMAN
UniProt ID (mouse)RFX3_MOUSE
UniProt AC (human)P48380
(TFClass)
UniProt AC (mouse)P48381
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 1 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
PCM
ACGT
011402.253517.252181.252845.25
02824.754254.753121.751744.75
0386.012.09813.035.0
047.036.017.09886.0
05600.0200.04.09142.0
061928.019.07484.0515.0
071.09099.014.0832.0
082.06611.015.03318.0
099552.066.097.0231.0
10726.0252.0848.08120.0
11979.0164.08692.0111.0
12857.0778.08013.0298.0
132755.252655.251495.253040.25
144630.5788.52582.51944.5
PFM
ACGT
010.1410.3540.2190.286
020.0830.4280.3140.175
030.0090.0010.9870.004
040.0010.0040.0020.994
050.060.020.00.919
060.1940.0020.7520.052
070.00.9150.0010.084
080.00.6650.0020.334
090.960.0070.010.023
100.0730.0250.0850.816
110.0980.0160.8740.011
120.0860.0780.8060.03
130.2770.2670.150.306
140.4660.0790.260.196
PWM
ACGT
01-0.5720.347-0.1310.135
02-1.1020.5370.227-0.354
03-3.339-5.1591.372-4.201
04-5.589-4.174-4.8591.38
05-1.419-2.51-5.9791.301
06-0.254-4.7611.101-1.571
07-6.6251.297-5.028-1.093
08-6.3610.977-4.9690.288
091.345-3.596-3.221-2.367
10-1.229-2.281-1.0741.183
11-0.931-2.7061.251-3.09
12-1.063-1.161.17-2.115
130.1030.066-0.5080.201
140.621-1.1470.038-0.246
Standard thresholds
P-value Threshold
0.001 2.61876
0.0005 3.93011
0.0001 6.608765